一例食蟹猴肠套叠诊断与治疗
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摘要
长期毒性试验中,一只食蟹猴发生肠套叠,结合临床症状、血液生化指标检测、触诊和B超等方法确诊,采用体外按摩法复位套叠肠段,复位后采取补充能量、解痉、限食等护理措施,动物恢复良好,毒性试验如期进行。结果表明,触诊和B超相结合的方法,可准确诊断早期肠套叠;采用体外按摩法可有效治疗早期肠套叠,且不影响长期毒性试验开展。
Intussusception occurred in a cynomolgus during a repeat dose toxicity study. Intussusception of cynomolgus was diagnosed by using the methods of clinical observation, hematology and plasma chemistry analysis, palpation and bultrasonic. Reset the intussusceptions by manually in vitro. The actions of supplying energy and antispasmodic drug and dietary restriction were performed for nursing.The animal recovered very well, and the toxicity study proceeded as scheduled. The results indicated that the inchoate intussusception could be correctly diagnosed by using the methods of palpation and bultrasonic;and the inchoate intussusceptions could be effective treated by manually in vitro, and the repeat dose toxicity study wouldn't be influenced.
Intussusception occurred in a cynomolgus during a repeat dose toxicity study. Intussusception of cynomolgus was diagnosed by using the methods of clinical observation, hematology and plasma chemistry analysis, palpation and bultrasonic. Reset the intussusceptions by manually in vitro. The actions of supplying energy and antispasmodic drug and dietary restriction were performed for nursing.The animal recovered very well, and the toxicity study proceeded as scheduled. The results indicated that the inchoate intussusception could be correctly diagnosed by using the methods of palpation and bultrasonic;and the inchoate intussusceptions could be effective treated by manually in vitro, and the repeat dose toxicity study wouldn't be influenced.
引文
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[7]Martinez Sanz N,González Valverde FM.Intussusception after bariatric surgery[J].J Gastrointest Surg,2019,23(3):597-598.
[8]吴艳艳,陈琴,李治熹,等.超声引导下生理盐水灌肠复位治疗小儿肠套叠的临床价值研究[J].西南医科大学学报,2018,41(4):317-321.
[9]匡德宣,叶尤松,罗志武,等.恒河猴肠套叠的B超诊断与手术治疗[J].中国比较医学杂志,2010,20(9):79-82.
[2]Matsuo K,Inoue M,Shirai Y,et al.A rare case of primary small bowel de-differentiated liposarcoma causing intussusception:A case report[J].2018,97(24):A251.
[3]许定泽,赛白.猕猴肠套叠86例[J].上海实验动物科学,1990,10(4):237.
[4]陈静.一例川金丝猴肠套叠的病例报告[J].畜牧与饲料科学,2011,32(5):94.
[5]崔春生,崔伟,麻山河,等.犬肠套叠的病因与诊治[J].兽医临诊,2016,4(324):91-93.
[6]杨德吉,范涤,尚学东.犬的人工肠套叠初期钡灌肠影像观察[J].中国兽医科技,1996,26(7):31-32.
[7]Martinez Sanz N,González Valverde FM.Intussusception after bariatric surgery[J].J Gastrointest Surg,2019,23(3):597-598.
[8]吴艳艳,陈琴,李治熹,等.超声引导下生理盐水灌肠复位治疗小儿肠套叠的临床价值研究[J].西南医科大学学报,2018,41(4):317-321.
[9]匡德宣,叶尤松,罗志武,等.恒河猴肠套叠的B超诊断与手术治疗[J].中国比较医学杂志,2010,20(9):79-82.