摘要
载脂蛋白B在脂类代谢、胆固醇的运输中起关键性的作用,其在心血管疾病、家族性β脂蛋白血症、肥胖等疾病的研究中尤为重要。现对载脂蛋白B独特的基因结构和表达模式、脂蛋白滞留应答中的作用以及与动脉粥样硬化性心血管疾病的相关性和预测作用的研究进展做一综述。
Apolipoprotein B( apo B) plays an essential role in the metabolism of lipids and transport of cholesterol.Apo B is also one of the essential factors in the research of coronary artery disease,familial dysbetalipoproteinemia,obesity and other diseases. This paper reviews the research progress of the apo B gene's peculiar structure and expression patterns,the role of apo B in the lipoprotein response-toretention model and the correlation and prediction of apo B for the atherosclerotic cardiovascular disease.
引文
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