胃癌患者舌象特征研究概述
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摘要
舌诊是中医诊断中较为客观的诊断方法,利用现代的光学分析技术能客观地反映出舌象的变化特点,能为中医辨证诊断提供客观依据。胃癌患者证型以及体质的变化直接反映于舌,通过更加客观化、微观化、智能化的舌象研究方法,可以探寻胃癌证型变化过程中舌象的诊断意义。本文概述了胃癌患者不同证型与舌象特征研究、胃癌患者与正常人的舌象特征比较、胃癌患者不同病理分型的舌象研究、胃癌患者治疗前后舌象临床观察、胃癌患者舌象与实验室指标的相关性研究,概述胃癌患者的舌象特征研究进展,以期为胃癌与舌象相关性研究提供参考,为胃癌的临床诊疗提供一定科学依据。
Tongue diagnosis is a more objective diagnostic method in traditional Chinese medicine(TCM) diagnosis.Using modern optical analysis technology can objectively reflect the changing features of tongue images and provide an objective basis for TCM diagnosis. The changes of syndrome type and body constitution of patients with gastric cancer are directly reflected in the tongue. Through more objective, micro and intelligent methods of tongue study, the diagnostic significance of tongue in the process of syndrome differentiation of gastric cancer can be explored. This paper summarized the study of different syndrome types and tongue features of gastric cancer patients, comparison of tongue features of gastric cancer patients with normal subjects, tongue researches of different pathological types of gastric cancer patients, clinical observation of tongue symptoms of gastric cancer patients before and after treatment, laboratory index correlation research, overview of tongue cancer patients with the study of tongue features, in order to provide a reference for the study of the relationship between gastric cancer and tongue, providing a scientific basis for the clinical diagnosis and treatment of gastric cancer.
Tongue diagnosis is a more objective diagnostic method in traditional Chinese medicine(TCM) diagnosis.Using modern optical analysis technology can objectively reflect the changing features of tongue images and provide an objective basis for TCM diagnosis. The changes of syndrome type and body constitution of patients with gastric cancer are directly reflected in the tongue. Through more objective, micro and intelligent methods of tongue study, the diagnostic significance of tongue in the process of syndrome differentiation of gastric cancer can be explored. This paper summarized the study of different syndrome types and tongue features of gastric cancer patients, comparison of tongue features of gastric cancer patients with normal subjects, tongue researches of different pathological types of gastric cancer patients, clinical observation of tongue symptoms of gastric cancer patients before and after treatment, laboratory index correlation research, overview of tongue cancer patients with the study of tongue features, in order to provide a reference for the study of the relationship between gastric cancer and tongue, providing a scientific basis for the clinical diagnosis and treatment of gastric cancer.
引文
1王忆勤.中医诊断学.北京:高等教育出版社,2016:1,28-31.
2陶丽,杨金坤.胃癌中医辨证分型的文献分析.中医药学刊,2006,24(4):684-686.
3孙大志,修丽娟,等.胃癌中医证候多元分析.中国中医药信杂志,2016,23(10):16-20.
4 Sun D Z,Liu L,Jiao J P,et al.Syndrome characteristics of traditional Chinese medicine:summary of a clinical survey in 767 patients with gastric cancer.J Int Med,2010,8(4):332-40.
5陈涛,李丹.胃癌中医证型的文献分析.时珍国医国药,2006,17(4):661-663.
6丁园园.胃癌中医证型、证候及相关性研究.沈阳:辽宁中医药大学硕士学位论文,2010.
7王长洪,陆宇平,陈山泉,等.10216例胃病患者消化内镜与舌诊观察,中国中西医结合学会第十五次全国消化系统疾病学术研讨会,2003.
8秦吉华.胃癌患者舌涂片细胞学观察.第二次全国中西医结合诊断学术研讨会,2008,7:15-16.
9秦吉华,王莉,等.胃癌患者舌象与舌上皮细胞关系初探--附50例分析.中西医结合杂志,1987,7(1):30-32+5.
10黄志新,周福生,等.经纤维胃镜诊为胃癌的179例临床资料分析.广州中医药大学学报,1998,15(1):48-50.
11牛素蒲,赵礼一.浅析舌诊与上消化道疾病的关系.中国实用医药,2007,2(33):92-93.
12范德荣,林瑞奋,林欣,等.胃癌患者舌象与病机分析.中医杂志,1991(10):34-35.
13林晓东.60例胃癌病的舌下象观察.中国中西医结合学会第一届全国中西医结合诊断学术会议,2006:1.
14 Hu J,Han S,Chen Y,et al.Variations of tongue coating microbiota in patients with gastric cancer.Biomed Res Int,2015,2015:173729.
15董伟,吴娟,张军峰,等.胃癌患者舌苔及血清表皮生长因子与实验室指标的关系.中医杂志,2013,54(1):51-54.
16陈鲁媛,路广晁.114例胃癌患者舌象分析.中医杂志,2011,52(22):1935-1938.
17毛丹,陈孟溪.初诊胃癌患者胃镜象与舌象的相关性研究.中医药导报,2011,17(05):17-19.
18王正德,何英红,刘凌宇,等.初诊胃癌患者胃镜象与舌象的相关性研究.新中医,2011,43(8):95-97.
19诸兆虎,蔡慎初,许立华.胃癌及“癌前病变”的舌象观察与探讨(摘要).中西医结合杂志,1985(1):29.
20罗丹.早期胃癌病理分型与中医舌象、证型相关性的临床研究.福州:福建中医药大学硕士学位论文,2015.
21李廷廷.胃癌的舌色特点与其相关因素的分析.济南:山东中医药大学硕士学位论文,2014.
22毕茂华.100例晚期癌症患者舌象观察.世界中医药学会联合会第三届国际传统医药大会,2004:2.
23朱为康,李雁,候风刚,等.胃癌患者化疗前后中医证候临床观察.中华中医药学刊,2012,30(5):1180-1182.
24彭喜娜.胃癌患者化疗前后中医证候临床观察分析.光明中医,2017,32(8):1112-1113.
25郭宁栎.胃癌患者化疗前后舌象变化的临床研究.成都:成都中医药大学硕士学位论文,2015.
26李东芳,焦蕉,胡亚,等.应用聚类分析探讨胃癌术后中医证型分布规律的临床研究.湖南中医药大学学报,2016,36(9):90-92+97.
27周阿高,董佳容,李琰,等.消化系统肿瘤患者舌象研究概况.中医文献杂志,2011,29(1):54-56.
28周阿高,董佳容,洪声,等.恶性肿瘤患者舌象的研究进展.浙江中医杂志,2006,(12):726-729.
29于慧,殷东风.256例原发性胃癌中医证候特点及演变规律.中华中医药学刊,2012,30(7):1654-1656.
30林景松,洪茜,李宏良.胃癌患者瘀血舌象与血清人上皮生长因子水平关系的研究.新中医,2010,42(5):23-24.
31王莉,秦吉华,迟永利,等.106例胃癌患者舌苔脱落细胞观察.山东中医学院学报,1995,19(4):258-260.
32陈建建,陈兴华,万惠珍.胃癌患者紫暗舌与血液流变学检测的临床观察.现代诊断与治疗,1995,6(3):181.
33周阿高,丁钰熊,何素英,等.胃癌患者紫暗舌与血凝指标检测的相关性研究.上海中医药杂志,1993(12):6-7.
34沈霖,邹小娟,雷蕴瑛.胃癌患者的舌色变化与血清溶菌酶活力关系的探讨.上海中医药杂志,1988(11):14-16.
35侯亮,王瑞平.消化系统肿瘤患者舌苔脱落细胞EGFR表达及唾液EFG含量研究.南京中医药大学学报,2003,19(3),141-143.
2陶丽,杨金坤.胃癌中医辨证分型的文献分析.中医药学刊,2006,24(4):684-686.
3孙大志,修丽娟,等.胃癌中医证候多元分析.中国中医药信杂志,2016,23(10):16-20.
4 Sun D Z,Liu L,Jiao J P,et al.Syndrome characteristics of traditional Chinese medicine:summary of a clinical survey in 767 patients with gastric cancer.J Int Med,2010,8(4):332-40.
5陈涛,李丹.胃癌中医证型的文献分析.时珍国医国药,2006,17(4):661-663.
6丁园园.胃癌中医证型、证候及相关性研究.沈阳:辽宁中医药大学硕士学位论文,2010.
7王长洪,陆宇平,陈山泉,等.10216例胃病患者消化内镜与舌诊观察,中国中西医结合学会第十五次全国消化系统疾病学术研讨会,2003.
8秦吉华.胃癌患者舌涂片细胞学观察.第二次全国中西医结合诊断学术研讨会,2008,7:15-16.
9秦吉华,王莉,等.胃癌患者舌象与舌上皮细胞关系初探--附50例分析.中西医结合杂志,1987,7(1):30-32+5.
10黄志新,周福生,等.经纤维胃镜诊为胃癌的179例临床资料分析.广州中医药大学学报,1998,15(1):48-50.
11牛素蒲,赵礼一.浅析舌诊与上消化道疾病的关系.中国实用医药,2007,2(33):92-93.
12范德荣,林瑞奋,林欣,等.胃癌患者舌象与病机分析.中医杂志,1991(10):34-35.
13林晓东.60例胃癌病的舌下象观察.中国中西医结合学会第一届全国中西医结合诊断学术会议,2006:1.
14 Hu J,Han S,Chen Y,et al.Variations of tongue coating microbiota in patients with gastric cancer.Biomed Res Int,2015,2015:173729.
15董伟,吴娟,张军峰,等.胃癌患者舌苔及血清表皮生长因子与实验室指标的关系.中医杂志,2013,54(1):51-54.
16陈鲁媛,路广晁.114例胃癌患者舌象分析.中医杂志,2011,52(22):1935-1938.
17毛丹,陈孟溪.初诊胃癌患者胃镜象与舌象的相关性研究.中医药导报,2011,17(05):17-19.
18王正德,何英红,刘凌宇,等.初诊胃癌患者胃镜象与舌象的相关性研究.新中医,2011,43(8):95-97.
19诸兆虎,蔡慎初,许立华.胃癌及“癌前病变”的舌象观察与探讨(摘要).中西医结合杂志,1985(1):29.
20罗丹.早期胃癌病理分型与中医舌象、证型相关性的临床研究.福州:福建中医药大学硕士学位论文,2015.
21李廷廷.胃癌的舌色特点与其相关因素的分析.济南:山东中医药大学硕士学位论文,2014.
22毕茂华.100例晚期癌症患者舌象观察.世界中医药学会联合会第三届国际传统医药大会,2004:2.
23朱为康,李雁,候风刚,等.胃癌患者化疗前后中医证候临床观察.中华中医药学刊,2012,30(5):1180-1182.
24彭喜娜.胃癌患者化疗前后中医证候临床观察分析.光明中医,2017,32(8):1112-1113.
25郭宁栎.胃癌患者化疗前后舌象变化的临床研究.成都:成都中医药大学硕士学位论文,2015.
26李东芳,焦蕉,胡亚,等.应用聚类分析探讨胃癌术后中医证型分布规律的临床研究.湖南中医药大学学报,2016,36(9):90-92+97.
27周阿高,董佳容,李琰,等.消化系统肿瘤患者舌象研究概况.中医文献杂志,2011,29(1):54-56.
28周阿高,董佳容,洪声,等.恶性肿瘤患者舌象的研究进展.浙江中医杂志,2006,(12):726-729.
29于慧,殷东风.256例原发性胃癌中医证候特点及演变规律.中华中医药学刊,2012,30(7):1654-1656.
30林景松,洪茜,李宏良.胃癌患者瘀血舌象与血清人上皮生长因子水平关系的研究.新中医,2010,42(5):23-24.
31王莉,秦吉华,迟永利,等.106例胃癌患者舌苔脱落细胞观察.山东中医学院学报,1995,19(4):258-260.
32陈建建,陈兴华,万惠珍.胃癌患者紫暗舌与血液流变学检测的临床观察.现代诊断与治疗,1995,6(3):181.
33周阿高,丁钰熊,何素英,等.胃癌患者紫暗舌与血凝指标检测的相关性研究.上海中医药杂志,1993(12):6-7.
34沈霖,邹小娟,雷蕴瑛.胃癌患者的舌色变化与血清溶菌酶活力关系的探讨.上海中医药杂志,1988(11):14-16.
35侯亮,王瑞平.消化系统肿瘤患者舌苔脱落细胞EGFR表达及唾液EFG含量研究.南京中医药大学学报,2003,19(3),141-143.