围产儿出生缺陷监测分析与干预措施
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摘要
目的研究围产儿出生缺陷发生率与干预现状,并提出对应干预措施。方法回顾性分析2015年10月—2018年10月本市三家省级出生缺陷监测医院围产儿出生缺陷资料,根据《中国出生缺陷医院监测方案》中23类出生缺陷的定义、诊断标准以及特征实施临床检测。分析缺陷发生率,缺陷发生于产妇年龄关系及婚检关系。结果缺陷发生率为2.26%,3年间呈上升趋势。产妇年龄> 35岁时缺陷发生率最高,差异有统计学意义(P <0.05);婚检组围产儿出生缺陷发生率为1.01%,低于未婚检组(5.72%),差异具有统计学意义(P <0.05)。结论婚检与适龄生产可降围产儿出生缺陷发生率。
Objective To study the incidence and intervention status of perinatal birth defects, and put forward corresponding intervention measures. Methods The data of perinatal birth defects of perinatal babies in three provincial monitoring hospitals of birth defects in this city from October 2015 to October 2018 were retrospectively analyzed, and clinical tests were conducted according to the definition, diagnostic criteria and characteristics of 23 types of birth defects in the monitoring program of China birth defect hospitals. The incidence of defects was analyzed, and the defects occurred in the relationship between maternal age and premarital examination. Results The incidence of defect was 2.26%, which showed an upward trend in three years. The incidence of defects was the highest when the puerpera was older than 35 years old(P < 0.05). The incidence of perinatal birth defects in premarital examination group was 1.01%, lower than that in unmarried examination group(5.72%), the difference was statistically significant(P < 0.05). Conclusion The rate of birth defects of perinatal infants can be reduced by premarital examination and ageappropriate birth.
Objective To study the incidence and intervention status of perinatal birth defects, and put forward corresponding intervention measures. Methods The data of perinatal birth defects of perinatal babies in three provincial monitoring hospitals of birth defects in this city from October 2015 to October 2018 were retrospectively analyzed, and clinical tests were conducted according to the definition, diagnostic criteria and characteristics of 23 types of birth defects in the monitoring program of China birth defect hospitals. The incidence of defects was analyzed, and the defects occurred in the relationship between maternal age and premarital examination. Results The incidence of defect was 2.26%, which showed an upward trend in three years. The incidence of defects was the highest when the puerpera was older than 35 years old(P < 0.05). The incidence of perinatal birth defects in premarital examination group was 1.01%, lower than that in unmarried examination group(5.72%), the difference was statistically significant(P < 0.05). Conclusion The rate of birth defects of perinatal infants can be reduced by premarital examination and ageappropriate birth.
引文
[1]郝静,杨悦.B型超声检查联合血清筛查胎儿出生缺陷的应用价值[J].中华保健医学杂志,2018,20(5):432-433.
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[3]李兵,夏建红,田丰莲,等.广东省1996年至2004年监测出生缺陷发生情况分析[J].中华围产医学杂志,2006(6):396-399.
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[5]刘茜玙,陈红阳,周妙,等.株洲市2010-2014年出生缺陷监测结果分析与干预措施思考[J].中国妇幼卫生杂志,2015,6(5):25-27+37.
[6]曹奕,张高东,蒋秋静,等.重庆市2005至2015年出生缺陷医院监测主要结果分析[J].重庆医科大学学报,2017,42(8):990-993.
[7]邝红芳,刘兰萍.新生儿出生缺陷相关因素分析及干预措施[J].中国医药科学,2017,7(10):59-62.
[8]农铮,张玉,关海滨,等.柳州市柳南区2011-2015年人群出生缺陷监测结果分析[J].中国卫生统计,2016,33(6):1017-1019.
[9]徐昕,李士雪,赵思琪,等.山东省平阴县2001-2013年围产儿出生缺陷调查分析[J].中国儿童保健杂志,2015,23(8):859-861.
[10]谢菲,丁焱.国内外开展孕前保健服务的研究进展[J].中华护理杂志,2013,48(6):567-571.
[11]王月云,张燕茹,聂绍发,等.深圳市0~6岁儿童家长出生缺陷防治知识知晓情况分析[J].中华疾病控制杂志,2016,20(2):149-152.
[12]张立明,张秀敏,马跃.吉林省5岁以下儿童出生缺陷影响因素病例对照研究[J].中华疾病控制杂志,2018,22(7):667-671.
[2]李松,洪世欣,王太梅,等.出生缺陷监测及其应用[J].中华流行病学杂志,2001(3):16-19.
[3]李兵,夏建红,田丰莲,等.广东省1996年至2004年监测出生缺陷发生情况分析[J].中华围产医学杂志,2006(6):396-399.
[4]冼康明,陆坚,凌艳嫦,等.江门市新会区城乡出生缺陷监测情况及危险因素分析[J].中国妇幼保健,2015,30(3):390-392.
[5]刘茜玙,陈红阳,周妙,等.株洲市2010-2014年出生缺陷监测结果分析与干预措施思考[J].中国妇幼卫生杂志,2015,6(5):25-27+37.
[6]曹奕,张高东,蒋秋静,等.重庆市2005至2015年出生缺陷医院监测主要结果分析[J].重庆医科大学学报,2017,42(8):990-993.
[7]邝红芳,刘兰萍.新生儿出生缺陷相关因素分析及干预措施[J].中国医药科学,2017,7(10):59-62.
[8]农铮,张玉,关海滨,等.柳州市柳南区2011-2015年人群出生缺陷监测结果分析[J].中国卫生统计,2016,33(6):1017-1019.
[9]徐昕,李士雪,赵思琪,等.山东省平阴县2001-2013年围产儿出生缺陷调查分析[J].中国儿童保健杂志,2015,23(8):859-861.
[10]谢菲,丁焱.国内外开展孕前保健服务的研究进展[J].中华护理杂志,2013,48(6):567-571.
[11]王月云,张燕茹,聂绍发,等.深圳市0~6岁儿童家长出生缺陷防治知识知晓情况分析[J].中华疾病控制杂志,2016,20(2):149-152.
[12]张立明,张秀敏,马跃.吉林省5岁以下儿童出生缺陷影响因素病例对照研究[J].中华疾病控制杂志,2018,22(7):667-671.