肺康复训练联合药物治疗中重度COPD效果观察
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摘要
目的探究肺康复训练联合药物吸入治疗中重度慢性阻塞性肺疾病(COPD)患者疗效。方法选取2016年2月-2018年2月我院收治的中重度COPD患者140例,按照随机抽签法将患者分为观察组与对照组各70例,对照组予以沙美特罗替卡松雾化吸入,观察组采用肺康复训练联合沙美特罗替卡松雾化吸入治疗,观察两组患者治疗前后第一秒用力呼气容积与用力肺活量比值(FEV1/FVC)、1秒钟用力呼气容积占预测值百分比(FEV1%Pre)、最大自主通气量(MVV)、6min步行试验(6MWT)并记录及COPD评估测试(CAT)变化。结果治疗后两组患者FEV1/FVC、FEV1%Pre及MVV均明显高于治疗前(P<0.05),且观察组显著高于对照组(P<0.05);治疗后观察组6MWT显著高于对照组(P<0.05),CAT评分明显低于对照组(P<0.05)。结论肺康复训练联合沙美特罗替卡松吸入治疗中重度COPD可通过有效改善肺功能、增强运动耐力来患者提高生活质量。
Objective To explore the efficacy of pulmonary rehabilitation training combined with drug inhalation in the treatment of patients with moderate-to-severe chronic obstructive pulmonary disease(COPD). Methods A total of 140 patients with moderate-to-severe COPD admitted to our hospital from February 2016 to February 2018 were selected.According to the random sampling method, the patients were divided into observation group and control group, with70 cases in each group. Control group was treated with aerosol inhalation of salmeterol and fluticasone propionate, and observation group was given pulmonary rehabilitation training combined with aerosol inhalation of salmeterol and fluticasone propionate. The ratio of forced expiratory volume in 1 s and forced vital capacity(FEV1/FVC), percentage of forced expiratory volume in 1 s of predicted value(FEV1%Pre), maximum voluntary ventilation(MVV) and 6-min walking test(6 MWT) were observed in the two groups before and after treatment, and the COPD assessment test(CAT)was recorded. Results After treatment, the FEV1/FVC, FEV1% Pre and MVV in the two groups were significantly higher than those before treatment(P<0.05), and the indexes in observation group were significantly higher than those in control group(P<0.05). After treatment, the 6 MWT in observation group was significantly higher than that in control group(P<0.05), and the CAT score was significantly lower than that in control group(P<0.05). Conclusion Pulmonary rehabilitation training combined with salmeterol and fluticasone propionate inhalation can improve the quality of life by effectively improving pulmonary function and enhancing exercise tolerance in the treatment of moderate-to-severe COPD.
Objective To explore the efficacy of pulmonary rehabilitation training combined with drug inhalation in the treatment of patients with moderate-to-severe chronic obstructive pulmonary disease(COPD). Methods A total of 140 patients with moderate-to-severe COPD admitted to our hospital from February 2016 to February 2018 were selected.According to the random sampling method, the patients were divided into observation group and control group, with70 cases in each group. Control group was treated with aerosol inhalation of salmeterol and fluticasone propionate, and observation group was given pulmonary rehabilitation training combined with aerosol inhalation of salmeterol and fluticasone propionate. The ratio of forced expiratory volume in 1 s and forced vital capacity(FEV1/FVC), percentage of forced expiratory volume in 1 s of predicted value(FEV1%Pre), maximum voluntary ventilation(MVV) and 6-min walking test(6 MWT) were observed in the two groups before and after treatment, and the COPD assessment test(CAT)was recorded. Results After treatment, the FEV1/FVC, FEV1% Pre and MVV in the two groups were significantly higher than those before treatment(P<0.05), and the indexes in observation group were significantly higher than those in control group(P<0.05). After treatment, the 6 MWT in observation group was significantly higher than that in control group(P<0.05), and the CAT score was significantly lower than that in control group(P<0.05). Conclusion Pulmonary rehabilitation training combined with salmeterol and fluticasone propionate inhalation can improve the quality of life by effectively improving pulmonary function and enhancing exercise tolerance in the treatment of moderate-to-severe COPD.
引文
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[8]马小玉,安福成,李鹏飞,等.肺康复联合噻托溴铵对慢性阻塞性肺疾病稳定期患者BODE指数的影响[J].国际呼吸杂志,2016,36(19):1462-1466.
[2]江容飞,徐玲,李小华.肺康复训练联合吸入舒利迭与噻托溴铵对中重度COPD患者肺功能、运动耐力及生活质量的影响[J].实用临床医药杂志,2017,21(9):28-30.
[3]伏冉,郑玉龙,王贻,等.全面肺康复治疗对中、重度慢性阻塞性肺疾病患者稳定期肺功能和血气指标的影响[J].中华物理医学与康复杂志,2016,38(8):594-597.
[4]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2013年修订版)[J].中华结核和呼吸杂志,2013,36(4):255-264.
[5]李冬艳,韩保芬,闫薇.长期家庭氧疗联合肺康复训练对中重度稳定期慢性阻塞性肺疾病患者临床疗效的影响[J].中国药物与临床,2017,17(4):550-551.
[6]吴海燕,钱钧,李树雯,等.心肺康复运动训练对COPD稳定期患者肺功能的影响[J].中国康复医学杂志,2016,31(3):351-353.
[7]李红,刘燕,唐健滨,等.不同运动负荷量肺康复训练在稳定期慢性阻塞性肺疾病患者中应用效果的对比研究[J].实用心脑肺血管病杂志,2017,25(12):68-70.
[8]马小玉,安福成,李鹏飞,等.肺康复联合噻托溴铵对慢性阻塞性肺疾病稳定期患者BODE指数的影响[J].国际呼吸杂志,2016,36(19):1462-1466.