中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果
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摘要
目的:探析中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果。方法:选取我院于2016年1月—2017年12月收治的56例乳腺癌患者为主要研究对象,所有患者均接受乳腺癌改良根治术的术后化疗。采用数字随机表达法将其分为两组,对照组和观察组各28例。对照组患者给予西药方案调理,观察组患者给予中药益气健脾和胃法治疗,对两组患者的胃肠道不良反应(恶心呕吐、食欲下降、腹泻、便秘)发生情况、生存质量和术后复发情况进行对比分析。结果:(1)经治疗后,观察组患者在恶心呕吐、食欲下降、腹泻、便秘等胃肠不良反应方面的发生率明显低于对照组,两组数据对比差异有统计学意义(P<0.05);(2)两组患者治疗前的生存质量评分对比差异无统计学意义(P>0.05),观察组患者的各项生存质量评分明显高于对照组,两组差异有统计学意义(P<0.05);(3)观察组的术后复发率为17.86%,对照组患者的术后复发率为46.49%,经统计学分析,观察组的复发率明显低于对照组,两组对比差异显著,有统计学意义(P<0.05)。结论:中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果显著,同时可降低患者术后病灶的复发率,提高机体免疫力,从而提升患者的生存质量。中药调理方案兼具安全性和有效性,故值得在临床上进一步推广和应用。
Objective: To explore the effect of Effect of Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) on postoperative gastrointestinal reaction of patients with breast cancer after chemotherapy. Methods:56 breast cancer patients who were treated in our hospital from January 2016 to December 2017 were selected as the main study subjects. All patients received postoperative chemotherapy for modified radical mastectomy. They were divided into two groups by using the digital random method, with 28 cases in the control group and 28 cases in the observation group. Patients in the control group were given Western medicine regimen conditioning, and patients in the observation group were given Chinese herbal medicine Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) to treat gastrointestinal adverse reactions(nausea and vomiting, loss of appetite, diarrhea, constipation). The quality of life, and surgery for both groups of patients and the recurrence was given a comparative analysis. Results:1.After treatment, the incidence of nausea and vomiting, loss of appetite, diarrhea, constipation and other gastrointestinal adverse reactions were significantly lower in the observation group than that in the control group. There was a statistically significant difference between the two groups(P<0.05). 2.There was no significant difference in quality of life scores before treatment between the two groups(P>0.05). After treatment, the quality of life scores in the observation group were significantly higher than those in the control group. There was a statistically significant difference between the two groups(P<0.05); 3.The postoperative recurrence rate was 17.86% in the observation group and 46.49% in the control group. After statistical analysis, the recurrence rate in the observation group was significantly lower than that in the control group. There was a statistically significant difference between the two groups(P<0.05). Conclusion: The traditional Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) had a significant effect on postoperative gastrointestinal reaction in patients with breast cancer. It could also reduce the recurrence rate of postoperative lesions, improve the body immunity, and thus improve the quality of life of patients. The traditional Chinese medicine conditioning program was both safe and effective, so it was worth further promotion and application in clinical practice.
Objective: To explore the effect of Effect of Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) on postoperative gastrointestinal reaction of patients with breast cancer after chemotherapy. Methods:56 breast cancer patients who were treated in our hospital from January 2016 to December 2017 were selected as the main study subjects. All patients received postoperative chemotherapy for modified radical mastectomy. They were divided into two groups by using the digital random method, with 28 cases in the control group and 28 cases in the observation group. Patients in the control group were given Western medicine regimen conditioning, and patients in the observation group were given Chinese herbal medicine Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) to treat gastrointestinal adverse reactions(nausea and vomiting, loss of appetite, diarrhea, constipation). The quality of life, and surgery for both groups of patients and the recurrence was given a comparative analysis. Results:1.After treatment, the incidence of nausea and vomiting, loss of appetite, diarrhea, constipation and other gastrointestinal adverse reactions were significantly lower in the observation group than that in the control group. There was a statistically significant difference between the two groups(P<0.05). 2.There was no significant difference in quality of life scores before treatment between the two groups(P>0.05). After treatment, the quality of life scores in the observation group were significantly higher than those in the control group. There was a statistically significant difference between the two groups(P<0.05); 3.The postoperative recurrence rate was 17.86% in the observation group and 46.49% in the control group. After statistical analysis, the recurrence rate in the observation group was significantly lower than that in the control group. There was a statistically significant difference between the two groups(P<0.05). Conclusion: The traditional Chinese herbal medicine Yiqi Jianpi Hewei Therapy(益气健脾和胃法) had a significant effect on postoperative gastrointestinal reaction in patients with breast cancer. It could also reduce the recurrence rate of postoperative lesions, improve the body immunity, and thus improve the quality of life of patients. The traditional Chinese medicine conditioning program was both safe and effective, so it was worth further promotion and application in clinical practice.
引文
[1]陈庆,杨瑞萍.参苓健脾胃颗粒治疗乳腺癌化疗后胃肠道反应的疗效观察[J].临床医学研究与实践,2016,1(5):70-70.
[2]许炜茹,张青,富琦,等.疏肝健脾法联合化疗治疗晚期乳腺癌临床研究[J].世界中西医结合杂志,2016,11(6):815-818.
[3]徐川,于小伟,李莎罗,等.益气健脾汤联合化疗对乳腺癌生活质量和免疫功能的影响[J].陕西中医,2016,37(9):1160-1161.
[4]李文炜.中医益髓健脾汤对治疗晚期癌症患者化疗过程中骨髓抑制的影响效果探究[J].中国社区医师,2016,32(22):128-129.
[5]陈晓洁,杨洋,蒋鲁燕,等.改良中药热熨技术对改善乳腺癌患者化疗期胃肠道反应的效果[J].中华现代护理杂志,2016,22(3):369-372.
[6]贾震宇,李彦品,魏玉芳,等.扶正益髓方防治乳腺癌术后化疗骨髓抑制的临床研究[J].河北中医药学报,2017,32(1):20-22.
[7]韦富中,郑春璇,陈少勇.补肾健脾方联合CEF化疗方案时辰治疗在乳腺癌术后的应用研究[J].深圳中西医结合杂志,2017,27(7):119-122.
[8]罗明,石传科,徐丹,等.自拟中医汤剂对乳腺癌化疗患者的骨髓抑制及免疫功能指标水平的影响分析[J].中医临床研究,2015,18(15):119-120.
[9]潘志欣,程旭锋,沈秀华,等.温阳健脾理气汤联合穴位注射防治乳腺癌化疗后胃肠道不良反应临床研究[J].中医学报,2016,31(10):1442-1444.
[10]林晓明.中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的观察[J].中医临床研究,2016,8(1):76-77.
[2]许炜茹,张青,富琦,等.疏肝健脾法联合化疗治疗晚期乳腺癌临床研究[J].世界中西医结合杂志,2016,11(6):815-818.
[3]徐川,于小伟,李莎罗,等.益气健脾汤联合化疗对乳腺癌生活质量和免疫功能的影响[J].陕西中医,2016,37(9):1160-1161.
[4]李文炜.中医益髓健脾汤对治疗晚期癌症患者化疗过程中骨髓抑制的影响效果探究[J].中国社区医师,2016,32(22):128-129.
[5]陈晓洁,杨洋,蒋鲁燕,等.改良中药热熨技术对改善乳腺癌患者化疗期胃肠道反应的效果[J].中华现代护理杂志,2016,22(3):369-372.
[6]贾震宇,李彦品,魏玉芳,等.扶正益髓方防治乳腺癌术后化疗骨髓抑制的临床研究[J].河北中医药学报,2017,32(1):20-22.
[7]韦富中,郑春璇,陈少勇.补肾健脾方联合CEF化疗方案时辰治疗在乳腺癌术后的应用研究[J].深圳中西医结合杂志,2017,27(7):119-122.
[8]罗明,石传科,徐丹,等.自拟中医汤剂对乳腺癌化疗患者的骨髓抑制及免疫功能指标水平的影响分析[J].中医临床研究,2015,18(15):119-120.
[9]潘志欣,程旭锋,沈秀华,等.温阳健脾理气汤联合穴位注射防治乳腺癌化疗后胃肠道不良反应临床研究[J].中医学报,2016,31(10):1442-1444.
[10]林晓明.中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的观察[J].中医临床研究,2016,8(1):76-77.