2013—2017年江苏省荣军医院选择性5-HT再摄取抑制剂类抗抑郁药的使用情况分析
|
摘要
目的分析江苏省荣军医院2013—2017年选择性5-HT再摄取抑制剂(SSRIs)类抗抑郁药的使用情况,为临床合理用药和优化药品管理提供参考。方法收集江苏省荣军医院2013—2017年SSRIs的使用资料,利用Excel对药品金额、用药频度(DDDs)、日均费用(DDC)、药品排序比值(B/A)等进行分析。结果 2013—2017年SSRIs类抗抑郁药的销售金额呈上升趋势,艾司西酞普兰、舍曲林的销售金额与DDDs一直处于前列,氟伏沙明增长幅度最快。艾司西酞普兰的DDC相对较高,舍曲林和氟伏沙明的DDC相对较低。氟伏沙明的B/A值较高,其余各药物的B/A值接近于1。结论 2013—2017年江苏省荣军医院SSRIs类抗抑郁药的应用基本合理,药品的疗效是影响临床应用的关键,同时药物的经济性也是重要因素。
Objective To analyze the utilization of selective 5-HT reuptake inhibitors(SSRIs) of antidepressants in Jiangsu Rongjun Hospital from 2013 to 2017, and to provide reference for rational use and drug management. Methods The usage data of SSRIs in Jiangsu Rongjun Hospital from 2013 to 2017 were collected for analysis of consumption sum, frequency of drug use(DDDs), defined daily cost(DDC), and drug sequence ratio(B/A) by Excel. Results Consumption sum of SSRIs antidepressants showed an upward trend from 2013 to 2017. Consumption sum and DDDs of escitalopram and sertraline were at the forefront. And fluvoxamine increased the most rapidly. DDC of escitalopram was relatively high, while DDC of sertraline and fluvoxamine were relatively low. The B/A value of fluvoxamine was higher, and the B/A value of the other drugs was close to 1.00. Conclusion The application of SSRIs antidepressants in Jiangsu Rongjun Hospital from 2013 to 2017 is basically reasonable. The efficacy of drugs is the key to the clinical application, and the economy of drugs is also an important factor.
Objective To analyze the utilization of selective 5-HT reuptake inhibitors(SSRIs) of antidepressants in Jiangsu Rongjun Hospital from 2013 to 2017, and to provide reference for rational use and drug management. Methods The usage data of SSRIs in Jiangsu Rongjun Hospital from 2013 to 2017 were collected for analysis of consumption sum, frequency of drug use(DDDs), defined daily cost(DDC), and drug sequence ratio(B/A) by Excel. Results Consumption sum of SSRIs antidepressants showed an upward trend from 2013 to 2017. Consumption sum and DDDs of escitalopram and sertraline were at the forefront. And fluvoxamine increased the most rapidly. DDC of escitalopram was relatively high, while DDC of sertraline and fluvoxamine were relatively low. The B/A value of fluvoxamine was higher, and the B/A value of the other drugs was close to 1.00. Conclusion The application of SSRIs antidepressants in Jiangsu Rongjun Hospital from 2013 to 2017 is basically reasonable. The efficacy of drugs is the key to the clinical application, and the economy of drugs is also an important factor.
引文
[1]覃筱燕,周爽,杨曦光,等.浅谈抑郁症的神经行为学改变与发病机制研究进展[J].中央民族大学学报:自然科学版,2014,23(4):48-53.
[2]周少贤.近十年大学生抑郁情绪的发展趋势及应对策略[J].北京教育,2015(11):9-11.
[3]温李滔,潘胜茂,唐省三,等.公众对抑郁症态度及其影响因素分析[J].中国健康心理学杂志,2017,25(5):670-673.
[4]黄文武,费爱丽,沈禹泽,等.综合医院门诊抑郁障碍和焦虑障碍患者处方变化分析[J].中国现代应用药学,2016,33(9):1205-1208.
[5]张英,崔向丽,杨萍,等.SSRI和SNRI类抗抑郁药的不良反应[J].中国药物警戒,2010,7(9):554-555.
[6]李艳,丁庆明.限定日剂量在药物利用研究中的应用[J].中国执业药师,2010,7(9):6-8.
[7]张静,陈元成.2013-2015年天津市职业病防治院抗抑郁药使用情况分析[J].现代药物与临床,2016,31(7):1096.
[8]陈丽芳,娄建石.与细胞色素P4502D6相关的药物相互作用研究[J].中国药房,2008,19(29):2300.
[2]周少贤.近十年大学生抑郁情绪的发展趋势及应对策略[J].北京教育,2015(11):9-11.
[3]温李滔,潘胜茂,唐省三,等.公众对抑郁症态度及其影响因素分析[J].中国健康心理学杂志,2017,25(5):670-673.
[4]黄文武,费爱丽,沈禹泽,等.综合医院门诊抑郁障碍和焦虑障碍患者处方变化分析[J].中国现代应用药学,2016,33(9):1205-1208.
[5]张英,崔向丽,杨萍,等.SSRI和SNRI类抗抑郁药的不良反应[J].中国药物警戒,2010,7(9):554-555.
[6]李艳,丁庆明.限定日剂量在药物利用研究中的应用[J].中国执业药师,2010,7(9):6-8.
[7]张静,陈元成.2013-2015年天津市职业病防治院抗抑郁药使用情况分析[J].现代药物与临床,2016,31(7):1096.
[8]陈丽芳,娄建石.与细胞色素P4502D6相关的药物相互作用研究[J].中国药房,2008,19(29):2300.