养阴清肺汤和养阴清肺口服液治疗慢性咽炎的Meta分析
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摘要
目的:系统评价养阴清肺汤和养阴清肺口服液治疗慢性咽炎的有效性和安全性。方法:检索Pub Med、Medline、Web of Science、CBM、CNKI、VIP、万方数据库,养阴清肺汤和养阴清肺口服液治疗慢性咽炎的随机对照试验(RCT),检索时限至2017年2月。筛选文献、提取资料并对纳入研究进行资料提取及质量评估后,采用Rev Man 5.3软件进行Meta分析。结果:共纳入9个RCT,1 046例患者;Meta分析结果显示:养阴清肺汤和养阴清肺口服液单用治疗慢性咳嗽有效率优于常规治疗(RR=1.27,95%CI[1.18,1.35],P<0.00001);且常规治疗方案联合养阴清肺汤(口服液)有效率优于常规治疗(RR=1.42,95%CI[1.22,1.65],P<0.00001)。结论:养阴清肺汤(口服液)单用或者联合常规治疗具有更好的临床疗效。
Objective: To systematically evaluate the efficacy and safety of Yangyin Qingfei Decoction and Yangyin Qingfei Oral Liquid for chronic pharyngitis. Methods: The randomized controlled trials(RCT) of Yangyin Qingfei Decoction and Yangyin Qingfei Oral Liquid on chronic pharyngitis were searched through Pub Med, Medline, Web of Science, CBM, CNKI, VIP, Wanfang Database from inception to February, 2017. Meanwhile, after screening the literature, extracting the data and making the inclusion data extraction and quality assessment, the Rev Man 5.3 software was used for Meta-analysis. Results: A total of 9 RCT was enrolled, including 1 046 patients. The results of Meta-analysis showed that Yangyin Qingfei Decoction(Oral Liquid) was better than conventional treatment for chronic cough(RR=1.27, 95%CI [1.18, 1.35], P<0.00001); And conventional treatment combined with Yangyin Qingfei Decoction(Yangyin Qingfei Oral Liquid) was superior to conventional treatment(RR=1.42, 95%CI[1.22, 1.65], P<0.00001). Conclusion: Yangyin Qingfei Decoction(Yangyin Qingfei Oral Liquid) or the combination with conventional treatment has better clinical efficacy.
Objective: To systematically evaluate the efficacy and safety of Yangyin Qingfei Decoction and Yangyin Qingfei Oral Liquid for chronic pharyngitis. Methods: The randomized controlled trials(RCT) of Yangyin Qingfei Decoction and Yangyin Qingfei Oral Liquid on chronic pharyngitis were searched through Pub Med, Medline, Web of Science, CBM, CNKI, VIP, Wanfang Database from inception to February, 2017. Meanwhile, after screening the literature, extracting the data and making the inclusion data extraction and quality assessment, the Rev Man 5.3 software was used for Meta-analysis. Results: A total of 9 RCT was enrolled, including 1 046 patients. The results of Meta-analysis showed that Yangyin Qingfei Decoction(Oral Liquid) was better than conventional treatment for chronic cough(RR=1.27, 95%CI [1.18, 1.35], P<0.00001); And conventional treatment combined with Yangyin Qingfei Decoction(Yangyin Qingfei Oral Liquid) was superior to conventional treatment(RR=1.42, 95%CI[1.22, 1.65], P<0.00001). Conclusion: Yangyin Qingfei Decoction(Yangyin Qingfei Oral Liquid) or the combination with conventional treatment has better clinical efficacy.
引文
[1]王又闻,黄辉,王键,等.十大新安名方.中华中医药杂志,2013,28(12):3600-3605
[2]郑梅涧.重楼玉钥(中医临床必读丛书).北京:人民卫生出版社,2006
[3]曹景诚,梁茂新.慢性咽炎辨证存在问题及对策.中华中医药杂志,2016,31(4):1332-1335
[4]Higgins J,Green S.Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0.http://www.cochrane.org/training/cochrane-handbook.2011-07
[5]张丽辉,张永昌,王兵.养阴清肺法治疗慢性咳嗽38例.光明中医,2016,31(2):239-241
[6]孙世华.养阴清肺汤加减治疗慢性咽炎20例疗效观察.新中医,2010,42(10):81-81
[7]安立,李林.养阴清肺汤联合西药治疗慢性咽炎随机平行对照研究.实用中医内科杂志,2016,30(3):61-63
[8]赵秀贞.用养阴清肺汤治疗慢性咽炎的远期疗效与安全性分析.当代医药论丛,2014,12(15):14-16
[9]穆传军,李振山,孙兆勋.养阴清肺口服液治疗慢性咽炎80例疗效观察.山东中医杂志,2006,25(2):91-92
[10]赵玲.养阴清肺汤加减治疗慢性咽炎的疗效分析.浙江中西医结合杂志,1994,4(4):11-11
[11]曾云芳.养阴清肺汤治疗慢性咽炎的疗效分析.中国医药科学,2011,1(17):118
[12]姜乐生.中药配方颗粒治疗慢性咽炎80例临床疗效观察.中医临床研究,2013,5(15):26-28
[13]李莉,刘存华.养阴清肺合剂治疗慢性咽炎的临床研究.中西医结合心脑血管病杂志,2001,17(3):11-13
[14]唐元瑜,纪立金.水象思维下对温病养阴生津法治疗作用的再认识.中华中医药杂志,2017,32(2):432-434
[2]郑梅涧.重楼玉钥(中医临床必读丛书).北京:人民卫生出版社,2006
[3]曹景诚,梁茂新.慢性咽炎辨证存在问题及对策.中华中医药杂志,2016,31(4):1332-1335
[4]Higgins J,Green S.Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0.http://www.cochrane.org/training/cochrane-handbook.2011-07
[5]张丽辉,张永昌,王兵.养阴清肺法治疗慢性咳嗽38例.光明中医,2016,31(2):239-241
[6]孙世华.养阴清肺汤加减治疗慢性咽炎20例疗效观察.新中医,2010,42(10):81-81
[7]安立,李林.养阴清肺汤联合西药治疗慢性咽炎随机平行对照研究.实用中医内科杂志,2016,30(3):61-63
[8]赵秀贞.用养阴清肺汤治疗慢性咽炎的远期疗效与安全性分析.当代医药论丛,2014,12(15):14-16
[9]穆传军,李振山,孙兆勋.养阴清肺口服液治疗慢性咽炎80例疗效观察.山东中医杂志,2006,25(2):91-92
[10]赵玲.养阴清肺汤加减治疗慢性咽炎的疗效分析.浙江中西医结合杂志,1994,4(4):11-11
[11]曾云芳.养阴清肺汤治疗慢性咽炎的疗效分析.中国医药科学,2011,1(17):118
[12]姜乐生.中药配方颗粒治疗慢性咽炎80例临床疗效观察.中医临床研究,2013,5(15):26-28
[13]李莉,刘存华.养阴清肺合剂治疗慢性咽炎的临床研究.中西医结合心脑血管病杂志,2001,17(3):11-13
[14]唐元瑜,纪立金.水象思维下对温病养阴生津法治疗作用的再认识.中华中医药杂志,2017,32(2):432-434