苦马豆素与波状芽管蠕孢属内生真菌关系的研究进展
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摘要
疯草是含有苦马豆素的豆科棘豆属和黄芪属有毒植物的统称,家畜过量采食会发生以神经系统机能紊乱为特征的慢性中毒病。疯草的主要毒性成分为吲哚里西啶生物碱苦马豆素,波状芽管蠕孢属内生真菌在疯草中普遍存在,该属真菌与疯草中苦马豆素产生、含量及疯草毒性关系密切。文章对疯草中的苦马豆素和波状芽管蠕孢属内生真菌之间的关系进行综述,旨在为动物疯草中毒病的防控提供参考。
Locoweed is a common name for some poisonous species of Oxytropis spp. and Astragalus spp. that contain swainsonine. Excessively consumed the plants,animals can cause chronic poisoning disease characterized by nervous system dysfunction. The swainsonine( Indolizidine alkaloid) is mainly responsible for the toxicity of locoweed. Undifilum species fungal endophytes can commonly infect locoweeds. The presence of Undifilum endophytes is closely correlated with the concentration or producing of swainsonine in tissus of locoweeds. In this paper,the correlation between swainsonine and Undifilum species fungal endophytes from locoweeds was summarized. The aim of the present paper was to provide reference for preventing and controling animal locoweed poisoning.
Locoweed is a common name for some poisonous species of Oxytropis spp. and Astragalus spp. that contain swainsonine. Excessively consumed the plants,animals can cause chronic poisoning disease characterized by nervous system dysfunction. The swainsonine( Indolizidine alkaloid) is mainly responsible for the toxicity of locoweed. Undifilum species fungal endophytes can commonly infect locoweeds. The presence of Undifilum endophytes is closely correlated with the concentration or producing of swainsonine in tissus of locoweeds. In this paper,the correlation between swainsonine and Undifilum species fungal endophytes from locoweeds was summarized. The aim of the present paper was to provide reference for preventing and controling animal locoweed poisoning.
引文
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[5]HARRIS C M,CAMPBELL B C,MOLYNEUX R J,et al.Biosynthesis of swainsonine in the diablo loeoweed(Astragalus and Oxphyrus)[J].Tetrhhedron Lett,1988,29(38):4815-4818.
[6]BRAUN K,COOK T,LIDDELL C M.Locoism of cattle caused by a species of Alternaria[J].Phytopathology,1997,87:11-12.
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[9]卢萍.内蒙古三种棘豆属植物中苦马豆素相关因子的研究[D].呼和浩特:内蒙古农业大学,2007.
[10]余永涛.产苦马豆素疯草内生真菌的分离鉴定及其遗传多态性研究[D].杨凌:西北农林科技大学,2009.
[11]PRYOR B M,CREAMER R S,SHOEMAKER A R,et al.Undifilum,a new genus for endophytic Embellisia oxytropis and parasitic Helminthosporium bornmuelleri on legumes[J].Botany,2009,87:178-194.
[12]OLDRUP E,MCLAIN R J,PADILLA A,et al.Localization of endophytic Undifilum fungi in locoweed seed and influence of environmental parameters on a locoweed in vitro culture system[J].Botany,2010,88:512-521.
[13]BACON C W,WHITE J F,STONE J K.An overview of endophytic microbes[J].Microbial Endophytes,2000,3:29-33.
[14]CREAMER R,MCLAINROMERO J,OLDRUP E,et al.Fungal endophytes of locoweed:an overview[J].Poisonous Plants,2007,3(7):338-344.
[15]周启武,路浩,何平,等.小花棘豆(Oxytropis glabra DC)内生真菌的分布特点[J].微生物学报,2013,53(5):478-485.
[16]REYNA R,COOKE P,GRUM D,et al.Detection and localization of the endophyte Undifilum oxytropis in locoweed tissues[J].Botany,2012,90:1229-1236.
[17]Mc LAIN R J,PADILL A,CREAMER R.Microscopic localization of Embellisia in seed and seedlings of southern speckle pod locoweed(Astragalus lentiginosus)[J].Phytopathology,2004,94(6):69.
[18]COOK D,GARDNER D R,RALPHS M H,et al.Swainsonine concentrations and endophyte amounts of Undifilum oxytropis in different plant parts of Oxytropis sericea[J].J Chem Ecol,2009,35(10):1272-1278.
[19]RALPHS M H,COOK D,GARDNER D R,et al.Transmission of the locoweed endophyte to the next generation of plants[J].Fungal Ecol,2011,4:251-255.
[2]MOLYNEUX R J,JAMES L F,PANTER K E,et al.Analysis and dis-tribution of swainsonine and related polyhydroxyindolizidine alkaloids by thin layer chromatography[J].Phytochem Anal,1991,2:125-129.
[3]曹光荣,李绍君,段得贤,等.黄花棘豆有毒成分的分离与鉴定[J].西北农业大学学报,1989,17(3):1-8.
[4]GARDNER D R,MOLYNEUX R J,RALPHS M H.Analysis of swainsonine:extractionmethods,detection,and measurement inpopulation of locoweeds(Oxytropis spp.)[J].J Agric Food Chem,2001,49(10):4573-4580.
[5]HARRIS C M,CAMPBELL B C,MOLYNEUX R J,et al.Biosynthesis of swainsonine in the diablo loeoweed(Astragalus and Oxphyrus)[J].Tetrhhedron Lett,1988,29(38):4815-4818.
[6]BRAUN K,COOK T,LIDDELL C M.Locoism of cattle caused by a species of Alternaria[J].Phytopathology,1997,87:11-12.
[7]BRAUN K,ROMERO J,LIDDELL C,et al.Production of swainsonine by fungal endophytes of locoweed[J].Mycol Res,2003,107(8):980-988.
[8]WANG Q,NA Q,NA G G H,et al.Embellisia oxytropis,a new species isolated from Oxytropis kansuensis in China[J].Mycotaxon,2006,95:255-260.
[9]卢萍.内蒙古三种棘豆属植物中苦马豆素相关因子的研究[D].呼和浩特:内蒙古农业大学,2007.
[10]余永涛.产苦马豆素疯草内生真菌的分离鉴定及其遗传多态性研究[D].杨凌:西北农林科技大学,2009.
[11]PRYOR B M,CREAMER R S,SHOEMAKER A R,et al.Undifilum,a new genus for endophytic Embellisia oxytropis and parasitic Helminthosporium bornmuelleri on legumes[J].Botany,2009,87:178-194.
[12]OLDRUP E,MCLAIN R J,PADILLA A,et al.Localization of endophytic Undifilum fungi in locoweed seed and influence of environmental parameters on a locoweed in vitro culture system[J].Botany,2010,88:512-521.
[13]BACON C W,WHITE J F,STONE J K.An overview of endophytic microbes[J].Microbial Endophytes,2000,3:29-33.
[14]CREAMER R,MCLAINROMERO J,OLDRUP E,et al.Fungal endophytes of locoweed:an overview[J].Poisonous Plants,2007,3(7):338-344.
[15]周启武,路浩,何平,等.小花棘豆(Oxytropis glabra DC)内生真菌的分布特点[J].微生物学报,2013,53(5):478-485.
[16]REYNA R,COOKE P,GRUM D,et al.Detection and localization of the endophyte Undifilum oxytropis in locoweed tissues[J].Botany,2012,90:1229-1236.
[17]Mc LAIN R J,PADILL A,CREAMER R.Microscopic localization of Embellisia in seed and seedlings of southern speckle pod locoweed(Astragalus lentiginosus)[J].Phytopathology,2004,94(6):69.
[18]COOK D,GARDNER D R,RALPHS M H,et al.Swainsonine concentrations and endophyte amounts of Undifilum oxytropis in different plant parts of Oxytropis sericea[J].J Chem Ecol,2009,35(10):1272-1278.
[19]RALPHS M H,COOK D,GARDNER D R,et al.Transmission of the locoweed endophyte to the next generation of plants[J].Fungal Ecol,2011,4:251-255.