脑出血后早发性癫痫发作的发生率及其影响因素的应用研究
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摘要
目的研究分析脑出血后患者早发性癫痫发作的发生率以及影响因素。方法选择我院接受治疗的20例脑出血患者,并对其进行回顾性分析,观察早发性癫痫发作的发生率,并使用统计学方法将早发性癫痫发作与影响因素进行分析。结果 20例脑出血患者中,3例患者存在早发性癫痫发作,占比15.0%,较为常见的发作类型为全身强直阵挛性;经过单因素分析:电解质紊乱、皮质出血、再发脑出血容易导致早发性癫痫发作;经过Logistic回归分析:出血次数以及部位、电解质情况与早发性癫痫发作之间存在紧密关系,而皮质出血是独立危险因素。结论脑出血后患者很容易出现早发性癫痫发作,而且发生率较高,而电解质紊乱、皮质出血、再发脑出血是影响早发性癫痫发作的原因,其中皮质出血是独立危险因素。
Objective To study the incidence of early epileptic seizures and the influencing factors in patientswith cerebral hemorrhage. Methods Twenty patients with cerebral hemorrhage treated in our hospital were selectedand analyzed retrospectively. The incidence of early epileptic seizures was observed. Statistical methods were used toanalyze the early epileptic seizures and their influencing factors. Results Among 20 patients with cerebral hemorrhage,3 patients had early epileptic seizures, accounting for 15.0%. The most common type of seizures was generalized tonicclonic seizures. Univariate analysis showed that electrolyte disturbance, cortical hemorrhage and recurrent cerebralhemorrhage were easy to lead to early epilepsy. Logistic regression analysis showed that there was a close relationshipbetween the number of bleeding, location, electrolyte status and early epileptic seizures, and cortical hemorrhage wasan independent risk factor. Conclusion Early epileptic seizures are easy to occur in patients with cerebral hemorrhage,and the incidence is high. Electrolyte disturbance, cortical hemorrhage and recurrent cerebral hemorrhage are thecauses of early epileptic seizures. Cortical hemorrhage is an independent risk factor.
Objective To study the incidence of early epileptic seizures and the influencing factors in patientswith cerebral hemorrhage. Methods Twenty patients with cerebral hemorrhage treated in our hospital were selectedand analyzed retrospectively. The incidence of early epileptic seizures was observed. Statistical methods were used toanalyze the early epileptic seizures and their influencing factors. Results Among 20 patients with cerebral hemorrhage,3 patients had early epileptic seizures, accounting for 15.0%. The most common type of seizures was generalized tonicclonic seizures. Univariate analysis showed that electrolyte disturbance, cortical hemorrhage and recurrent cerebralhemorrhage were easy to lead to early epilepsy. Logistic regression analysis showed that there was a close relationshipbetween the number of bleeding, location, electrolyte status and early epileptic seizures, and cortical hemorrhage wasan independent risk factor. Conclusion Early epileptic seizures are easy to occur in patients with cerebral hemorrhage,and the incidence is high. Electrolyte disturbance, cortical hemorrhage and recurrent cerebral hemorrhage are thecauses of early epileptic seizures. Cortical hemorrhage is an independent risk factor.
引文
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[11]曹栓柱,王艳州,李金泉,等.不同手术方式治疗高血压性脑出血术后中晚期癫痫的发生情况比较[J].河南医学研究,2016,25(9):1594-1595.
[12]赛群.探讨46例脑出血术后康复期患者癫痫发作的临床护理[J].世界最新医学信息文摘,2016,16(10):182-183.
[2]张正春,姚慧娟.脑卒中与卒中后继发性癫痫的相关性临床病例分析[J].泰山医学院学报,2016,37(9):1052-1053.
[3]Bladin CF.Seizures after stroke:a prospective multicenter study[J].Arch Neurol,2000,57(11):1617-1622.
[4]李延红,李雪芬,李香,等.再次脑出血早发癫痫危险因素探讨[J].河南大学学报(医学版),2016,35(3):162-164.
[5]曹栓柱,王艳州,尹红霞,等.高血压脑出血患者术后癫痫发作的影响因素分析[J].山东医药,2017,57(16):83-85.
[6]唐开第.46例急性脑血管病后继发癫痫临床特点分析[J].齐齐哈尔医学院学报,2016,37(21):2681-2682.
[7]孙伟.浅析脑卒中后癫痫患者的临床特点[J].当代医药论丛,2016,14(11):133-134.
[8]邱金华,孔令恩,蔡春生,等.脑卒中后癫痫的调查研究和诊治[J].齐齐哈尔医学院学报,2016,37(11):1451-1452.
[9]师丽波.脑血管病继发癫痫临床特点分析[J].中国实用医药,2017,12(2):116-118.
[10]杨小兰,刘明龙,陈杰,等.丙戊酸钠预防脑出血后癫痫发作的疗效评价[J].中国现代医生,2017,55(15):34-36.
[11]曹栓柱,王艳州,李金泉,等.不同手术方式治疗高血压性脑出血术后中晚期癫痫的发生情况比较[J].河南医学研究,2016,25(9):1594-1595.
[12]赛群.探讨46例脑出血术后康复期患者癫痫发作的临床护理[J].世界最新医学信息文摘,2016,16(10):182-183.