摘要
目的探讨育龄期妇女发生复发性流产(RSA)的相关危险因素,为早期防治提供依据。方法选取120例确诊的育龄期RSA患者为病例组,同期随机选取120例正常妊娠的孕妇为对照组,采用病例对照的研究方法,进行单因素比较法和多因素logistic回归法来筛选RSA的相关危险因素。结果多因素logistic回归分析结果显示,引起育龄期RSA患者发病的危险因素包括不良生活方式(OR=4.358)、不良心理因素(OR=2.826)、自身免疫疾病(OR=3.518)、生殖系统感染(OR=3.666)、获得性子宫异常(OR=5.038)及配偶精子质量差(OR=1.996)。结论引起育龄期妇女发生RSA的高危因素包括不良生活方式、心理因素、免疫性疾病、生殖道感染、子宫异常及男性因素等;应针对以上高危因素,早期采取防治措施,降低育龄期妇女的RSA发生率。
Objective To explore the correlated risk factors of recurrent spontaneous abortion(RSA)among women of childbearing age,so as to provide a basis for preventing and treating RSA.Methods 120 cases of RSA were chosen as case group,and the other 120 cases of normal pregnancy women were chosen as the control group in the meanwhile.With Case-Control study method,the correlated risk factors of RSA were screened by a single comparison method and multiple factors logistic regression method,respectively.Results Multiple factors logistic regression methods showed that the risk factors of RSA among women of childbearing age included bad lifestyle(OR=4.358),adverse psychological factors(OR=2.826),autoimmune disease(OR=3.518),reproductive system infection(OR=3.666),acquired uterine abnormalities(OR=5.038)and poor sperm quality of spouses(OR=1.996).Conclusion The high-risk factors of RSA among women of childbearing age contain bad lifestyle,psychological factor,immune disease,reproductive system infection,abnormality of uterus and male factors.In view of the above high-risk factors,early preventive measures should be taken to reduce the incidence of RSA among women of childbearing age.
引文
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