摘要
心脑血管病已经成为威胁我国人民健康的首要疾病,而胆固醇也因被认为是主要诱因而广为人知。但大多数人由于对胆固醇的认识不够而视其为"毒药",所以本文通过对胆固醇的合成、功能、类型等方面进行阐述,让更多的人们能够正确地认识胆固醇,保持合理的摄入量,促进身体健康。
Cardiovascular disease has become a primary disease that threatens people's health,and cholesterol is widely known as the main cause.But most people see it as a "poison" because they lack sufficient awareness about cholesterol.Therefore,this paper elaborates the synthesis,function and type of cholesterol,so that more people can correctly understand cholesterol,maintain reasonable intake and promote physical health.
引文
[1]Li JH,Mi SQ,Li YC,et al.The levels and distribution of the serum lipids in Chinese adults,2010.Chin J Prev Med 2012;46:607-12.
[2]邹思湘.动物生物化学[M].北京:中国农业出版社,2012:164.
[3]Lange Y,Ye J,Rigney M,Steck TL.Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol.J LipidRes 1999;40(12):2264-70.
[4]Yang W,Bai Y,Xiong Y,Zhang J,Chen S,Zheng X,et al.Potentiating the antitumour response of CD8+T cells by modulating cholesterol metabolism.Nature 2016;531(7596):651-5.
[5]朱宁.中国人动脉粥样硬化性心血管疾病降胆固醇治疗的特殊性[J].医学与哲学,2015;36(521):23-27.
[6]杨宝瑜,高天琦,李洋等.细胞胆固醇的生理功能及其代谢异常相关疾病的研究进展[J].中国细胞生物学学报,2017;39(12):1-9.
[7]Cholesterol Treatment Trialists Collaboration,Baigent C,Blackwell L,et al.Efficacy and safety of more intensive lowering of LDL cholesterol:a meta-analysis of data from 170,000participants in 26randomised trials.Lancet.2010;376:1670-1681.
[8]何绍芳,肖桐明,李依潇等.高脂血症患者饮食指导与心理行为干预疗效观察[J].中国医药导报,2012.