摘要
目的对肺腺癌GGNs的多排螺旋CT诊断在判定微浸润中的价值进行系统评估,为患者早期防治方案的个性化制定提供参考依据。方法以肺腺癌患者作为研究对象,在征得患者及其家属同意的前提下对所有入选的患者行多排螺旋CT检查,并收集所有入选患者的基本资料,采用ROC受试者特征曲线初步评估肺腺癌GGNs的多排螺旋CT诊断在判定微浸润中的诊断中的敏感性和特异性。结果本研究有效观察对象128例;多排螺旋CT对肺腺癌GGNs的诊断结果与患者原始诊断结果的差异没有统计学意义(χ~2=2. 218,P> 0. 05);多排螺旋CT结果对肺腺癌GGNs检测结果ROC曲线下面积为0. 783(95%CI:0. 636~0. 905);影响患者多排螺旋CT结果对肺腺癌GGNs诊断结果的相关因素包括患者年龄、是否患有呼吸系统慢性炎症、是否新发、吸烟年限(P均<0. 05)。结论肺腺癌GGNs的多排螺旋CT诊断在判定微浸润中具有较优质的诊断价值,但多排螺旋CT定性结果可能会受到患者自身因素的影响,在作出诊断时需结合相关资料进一步分析。
Objective To evaluate the value of multi-slice spiral CT in the diagnosis of GGNs in the diagnosis of microinvasion,and to provide a reference for the individuation of early prevention and treatment of lung adenocarcinoma. Methods Lung adenocarcinoma patients treated in department of respiratory medicine of a grade 3 A hospital were selected as study subjects. All patients were examined with multi-slice spiral CT with the consent of patients and their families. The basic data of all the patients were collected and the diagnostic value of multi-slice spiral CT( MSCT) in the diagnosis of pulmonary adenocarcinoma( GGNs) was preliminarily evaluated by using the characteristic curve of ROC subjects in the diagnosis of microinfiltration. Sensitivity and specificity. Results 128 cases were observed effectively. There was no significant difference between the results of multislice spiral CT and that of the original diagnosis of lung adenocarcinoma( P > 0. 05),and the area under the ROC curve of multislice spiral CT for pulmonary adenocarcinoma was 0. 783/95 CI: 0. 636/0. 905,which affected the results of multi-slice spiral CT in patients with lung adenocarcinoma. The factors associated with GGNs diagnosis of lung adenocarcinoma include age. Whether you have chronic inflammation of the respiratory system,whether it was new,and the number of years of smoking( Pall < 0. 05).0. 05. Conclusion Multi-slice spiral CT diagnosis of lung adenocarcinoma GGNs is valuable in the diagnosis of microinvasion,but the qualitative results of multi-slice spiral CT may be affected by the patient's own factors.
引文
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