头部银屑病经卡泊三醇搽剂结合中药外洗治疗的疗效分析
|
摘要
目的:分析头部银屑病经卡泊三醇搽剂结合中药外洗治疗的疗效及价值。方法:将本皮肤科2015年10月-2017年1月收治的78例头部银屑病患者采用随机数字表法分为研究组和对照组,每组39例。对照组用卡泊三醇搽剂治疗,另结合研究组在对照组治疗基础上结合中药外洗,比较两组治疗后的效果。结果:治疗后研究组PASI评分、血清IL-17、IL-23水平、CD3~+、CD4~+水平及总有效率均优于对照组,差异均有统计学意义(P<0.05);但两组CD8~+水平比较,差异无统计学意义,(P>0.05)。结论:头部银屑病经卡泊三醇搽剂结合中药外洗治疗的疗效显著,值得临床推广。
Objective:To analysis the curative effect and value of card berth triol liniment combined with traditional Chinese medicine(TCM) outside washing in the treatment of scalp psoriasis.Method:From October 2015 to January 2017,78 cases with head psoriasis who treated in our prevention station were selected,they were divided into study group and control group according to the random number table method,39 cases in each group.The control group was treated by Card berth triol liniment,the study group was washed by traditional Chinese medicine on the basis of the control group,the curative effect and value of the two groups were compared.Result:After the treatment,the PASI score,serum levels of IL-17, IL-23,CD3~+,CD4~+ and total effective rate of the study group were all better than those of the control group,the differences were statistically significant(P<0.05);but the CD8~+ level of the two groups was no significant differences(P>0.05).Conclusion: Card berth three alcohol liniment combined with traditional Chinese medicine(TCM) outside washing in the treatment of scalp psoriasis has definitely curative effective,worth clinical promotion.
Objective:To analysis the curative effect and value of card berth triol liniment combined with traditional Chinese medicine(TCM) outside washing in the treatment of scalp psoriasis.Method:From October 2015 to January 2017,78 cases with head psoriasis who treated in our prevention station were selected,they were divided into study group and control group according to the random number table method,39 cases in each group.The control group was treated by Card berth triol liniment,the study group was washed by traditional Chinese medicine on the basis of the control group,the curative effect and value of the two groups were compared.Result:After the treatment,the PASI score,serum levels of IL-17, IL-23,CD3~+,CD4~+ and total effective rate of the study group were all better than those of the control group,the differences were statistically significant(P<0.05);but the CD8~+ level of the two groups was no significant differences(P>0.05).Conclusion: Card berth three alcohol liniment combined with traditional Chinese medicine(TCM) outside washing in the treatment of scalp psoriasis has definitely curative effective,worth clinical promotion.
引文
[1]樊玉.308 nm准分子激光联合卡泊三醇搽剂治疗头部银屑病的疗效[J].中国继续医学教育,2016,8(5):170-171.
[2]杨颜龙,张禁,易松柏,等.阿维A胶囊联合复方甘草酸苷注射液治疗红皮病型银屑病30例临床观察[J].中国皮肤性病别杂志,2015,29(2):217-220.
[3]张武,马俊红,罗丽芳,等.百癣夏塔热胶囊联合青霉素治疗急性点滴型银屑病临床观察[J].新中医,2017,49(1):103-105.
[4]张少文,徐梦英,张涛,等.表没食子儿茶素没食子酸酯硬脂酸酯凝胶剂治疗银屑病的药效学[J].中国医院药学杂志,2015,35(9):798-801.
[5]石成方,赵志力.表皮细胞生长因子冻干粉和阿维A辅助物理光疗法治疗银屑病的效果[J].中国医药导报,2015,12(32):17-20.
[6]吴爱平.放血拔罐配合凉血消疕汤治疗寻常型银屑病45例[J].中国中医药现代远程教育,2017,15(1):84-85.
[7]张鸫媛,任万明,石春蕊,等.复方甘草酸苷与阿维A胶囊联合治疗银屑病疗效和安全性的系统评价[J].中国循证医学杂志,2013,13(1):112.
[8]吴瑶,李金娥,冯娜娜,等.金黄膏封包联合中药内服治疗斑块状银屑病疗效观察[J].实用中医药杂志,2017,33(2):135-136.
[9]孙晓晖,刘俊杰.自拟凉血止痒方辨证加减配合西医治疗寻常型银屑病血热证急性期临床观察[J].中国中医急症,2015,24(11):2007-2009.
[10]沈平,通佩文,张学广,等.卡泊三醇外涂软膏联合激光光疗治疗银屑病对患者血清TNF-α、IL-17、IL-23水平的影响[J].临床合理用药,2015,8(7):87-88.
[11]魏秀兰,许鹏光.苦参方加减外洗治疗头部银屑病疗效观察[J].实用中医药杂志,2014,30(1):50-51.
[12]王萍,黄咏梅.牛皮癣药浴Ⅰ号治疗血热型银屑病的临床效果观察[J].数理医药学杂志,2017,30(1):82-84.
[13]何素敏,张虹亚,刘涛峰,等.清热凉血解毒汤治疗血热型银屑病的疗效观察及其对外周血TNF-α和IL-4的影响[J].中医药临床杂志,2015,27(1):68-71.
[14]刘云贞,李春鸟.清热消肿洗剂熏蒸联合中医辨证论治口服中药治疗寻常性银屑病的疗效分析[J].陕西中医,2016,37(7):897-898.
[15]郑小帆,刘卉,黄英举,等.润燥止痒胶囊联合UVB治疗银屑病的效果及对T细胞亚群水平的影响[J].中国医药指导,2015,12(9):124-127.
[16]于浩森.探讨阿维A联合消银片治疗头部银屑病临床观察[J].中国继续医学教育,2016,8(26):199-200.
[17]梁育,杨志波.竹黄颗粒干预治疗寻常型银屑病(血热型)及对外周血中细胞因子表达水平的影响[J].中华中医药杂志,2015,30(5):1827-1829.
[18]姜颖娟,李元文,杨碧莲,等.卡泊三醇搽剂联合中药外洗治疗头部银屑病35例[J].环球中医药,2015,8(2):217-218.
[19]廖勇,游艳,李璐.紫丹银屑胶囊联合窄谱中波紫外线治疗银屑病的临床研究[J].中药药理与临床,2015,31(3):187-189.
[20]刘国栋,刘思瑶,杨海薇.郁金消银汤联合卡泊三醇治疗银屑病的效果及对外周血IFN-γ、IL-2、IL-4和IL-10的影响[J].中国中西医结合皮肤性病学杂志,2016,15(5):285-287.
[2]杨颜龙,张禁,易松柏,等.阿维A胶囊联合复方甘草酸苷注射液治疗红皮病型银屑病30例临床观察[J].中国皮肤性病别杂志,2015,29(2):217-220.
[3]张武,马俊红,罗丽芳,等.百癣夏塔热胶囊联合青霉素治疗急性点滴型银屑病临床观察[J].新中医,2017,49(1):103-105.
[4]张少文,徐梦英,张涛,等.表没食子儿茶素没食子酸酯硬脂酸酯凝胶剂治疗银屑病的药效学[J].中国医院药学杂志,2015,35(9):798-801.
[5]石成方,赵志力.表皮细胞生长因子冻干粉和阿维A辅助物理光疗法治疗银屑病的效果[J].中国医药导报,2015,12(32):17-20.
[6]吴爱平.放血拔罐配合凉血消疕汤治疗寻常型银屑病45例[J].中国中医药现代远程教育,2017,15(1):84-85.
[7]张鸫媛,任万明,石春蕊,等.复方甘草酸苷与阿维A胶囊联合治疗银屑病疗效和安全性的系统评价[J].中国循证医学杂志,2013,13(1):112.
[8]吴瑶,李金娥,冯娜娜,等.金黄膏封包联合中药内服治疗斑块状银屑病疗效观察[J].实用中医药杂志,2017,33(2):135-136.
[9]孙晓晖,刘俊杰.自拟凉血止痒方辨证加减配合西医治疗寻常型银屑病血热证急性期临床观察[J].中国中医急症,2015,24(11):2007-2009.
[10]沈平,通佩文,张学广,等.卡泊三醇外涂软膏联合激光光疗治疗银屑病对患者血清TNF-α、IL-17、IL-23水平的影响[J].临床合理用药,2015,8(7):87-88.
[11]魏秀兰,许鹏光.苦参方加减外洗治疗头部银屑病疗效观察[J].实用中医药杂志,2014,30(1):50-51.
[12]王萍,黄咏梅.牛皮癣药浴Ⅰ号治疗血热型银屑病的临床效果观察[J].数理医药学杂志,2017,30(1):82-84.
[13]何素敏,张虹亚,刘涛峰,等.清热凉血解毒汤治疗血热型银屑病的疗效观察及其对外周血TNF-α和IL-4的影响[J].中医药临床杂志,2015,27(1):68-71.
[14]刘云贞,李春鸟.清热消肿洗剂熏蒸联合中医辨证论治口服中药治疗寻常性银屑病的疗效分析[J].陕西中医,2016,37(7):897-898.
[15]郑小帆,刘卉,黄英举,等.润燥止痒胶囊联合UVB治疗银屑病的效果及对T细胞亚群水平的影响[J].中国医药指导,2015,12(9):124-127.
[16]于浩森.探讨阿维A联合消银片治疗头部银屑病临床观察[J].中国继续医学教育,2016,8(26):199-200.
[17]梁育,杨志波.竹黄颗粒干预治疗寻常型银屑病(血热型)及对外周血中细胞因子表达水平的影响[J].中华中医药杂志,2015,30(5):1827-1829.
[18]姜颖娟,李元文,杨碧莲,等.卡泊三醇搽剂联合中药外洗治疗头部银屑病35例[J].环球中医药,2015,8(2):217-218.
[19]廖勇,游艳,李璐.紫丹银屑胶囊联合窄谱中波紫外线治疗银屑病的临床研究[J].中药药理与临床,2015,31(3):187-189.
[20]刘国栋,刘思瑶,杨海薇.郁金消银汤联合卡泊三醇治疗银屑病的效果及对外周血IFN-γ、IL-2、IL-4和IL-10的影响[J].中国中西医结合皮肤性病学杂志,2016,15(5):285-287.