手术切除治疗脑肿瘤卒中的临床效果
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摘要
目的分析手术切除治疗脑肿瘤卒中临床效果。方法选取吉林省肿瘤医院脑外科在2008-12至2016-12期间收治的脑肿瘤卒中患者112例的临床资料进行回顾分析,常规药物治疗患者为对照组(n=52),手术治疗患者为观察组(n=60)。给予对照组常规药物治疗,观察组采用手术切除治疗。比较两组的治疗效果、并发症发生率及肿瘤复发率。结果经过不同方式治疗后,观察组总有效率(96.67%)明显高于对照组(71.15%),且差异具有统计学意义(χ~2=14.084,P<0.001);治疗结束后,两组并发症主要以听力下降、语言障碍及偏瘫为主,观察组并发症发生率(16.66%)显著低于对照组(36.54%),且差异具有统计学意义(χ~2=5.733,P=0.017);观察组肿瘤复发率(3.33%)显著低于对照组(17.31%),且差异具有统计学意义(χ~2=6.519,P=0.011)。结论手术切除治疗脑肿瘤卒中治疗效果显著,且并发症发生率和肿瘤复发率均明显低于药物治疗,值得临床推广。
Objective This study objective was to analyse the clinical effect of surgical removal of brain tumors.MethodsA total sample of 112 patients with brain tumor from a tumor hospital in Jilin Province from December 2008 to December 2016 were selected,and their clinical data was retrospectively analyzed.The control group(n=52) was given traditional medication treatment while the observation group(n=60) was treated with surgical excision.The therapeutic effect,the rates of complications and the frequency of recurrence were compared between the two groups.Results After different methods of treatment,the total effectiveness of the treatment of the observation group(96.67%) was significantly higher than that of the control group(71.15%),and the difference was statistically significant(χ2=14.084,P<0.001); the types of complications occurring in the two groups mainly covered hearing impairment,language disorders and hemiplegia,with the complications rate of observation group(16.66%) being significantly lower than that of the control group(36.54%),and the difference was statistically significant(χ2=5.733,P=0.017); the recurrence rate of observation group(3.33%) was significantly lower than that of the control group(17.31%),and the difference was statistically significant(χ2=6.519,P=0.011).ConclusionsThe effectiveness of surgical removal in the treatment of stroke caused by brain tumor is more evident than that of the traditional treatment with medication.The rates of complications and recurrence are significantly lower than that with drug therapy,therefore,surgical treatment for brain tumor has valuable clinical significance.
Objective This study objective was to analyse the clinical effect of surgical removal of brain tumors.MethodsA total sample of 112 patients with brain tumor from a tumor hospital in Jilin Province from December 2008 to December 2016 were selected,and their clinical data was retrospectively analyzed.The control group(n=52) was given traditional medication treatment while the observation group(n=60) was treated with surgical excision.The therapeutic effect,the rates of complications and the frequency of recurrence were compared between the two groups.Results After different methods of treatment,the total effectiveness of the treatment of the observation group(96.67%) was significantly higher than that of the control group(71.15%),and the difference was statistically significant(χ2=14.084,P<0.001); the types of complications occurring in the two groups mainly covered hearing impairment,language disorders and hemiplegia,with the complications rate of observation group(16.66%) being significantly lower than that of the control group(36.54%),and the difference was statistically significant(χ2=5.733,P=0.017); the recurrence rate of observation group(3.33%) was significantly lower than that of the control group(17.31%),and the difference was statistically significant(χ2=6.519,P=0.011).ConclusionsThe effectiveness of surgical removal in the treatment of stroke caused by brain tumor is more evident than that of the traditional treatment with medication.The rates of complications and recurrence are significantly lower than that with drug therapy,therefore,surgical treatment for brain tumor has valuable clinical significance.
引文
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[11]熊海洋,吴中亚,周相军.急性出血性脑卒中起病的脑转移瘤临床特点分析[J].医药与保健,2015(3):10-11.
[12]Bauer S,May C,Dionysiou D,et al.Multiscale modeling for image analysis of brain tumor studies[J].IEEE Trans Biomed Eng,2012,59(1):25-29.DOI:10.1109/TBME.2011.2163406.
[13]李坪.出血性瘤卒中的临床诊断及治疗体会[J].医药前沿,2014,3(33):229.DOI:10.3969/j.issn.2095-1752.2014.33.223.
[14]陈韶青.脑肿瘤卒中误诊为脑出血临床分析[J].吉林医学,2014,56(23):5167-5168.
[15]孙锐.手术治疗脑肿瘤出血的临床效果及临床特点分析[J].世界最新医学信息文摘,2016,16(13):94-96.DOI:10.3969/j.issn.1671-3141.2016.13.069.
[16]Tustison N J,Shrinidhi K L,Wintermark M,et al.Optimal symmetric multimodal templates and concatenated random forests for supervised brain tumor segmentation(Simplified)with ANTs R[J].Neuroinformatics,2015,13(2):209-225.DOI:10.1007/s12021-014-9245-2.
[17]Loizou C P,Murray V,Pattichis M S,et al.Despeckle filtering for multiscale amplitude-modulation frequencymodulation(AM-FM)texture Analysis of ultrasound images of the intima-media complex[J].Int J Biomed Imaging,2014(2014):518414.DOI:10.1155/2014/518414.
[2]刘鹏程,田波.手术治疗脑肿瘤出血的临床效果评价与特点分析[J].中国当代医药,2014,21(21):54-56.
[3]李国新.分析出血性脑瘤卒中的临床与CT表现以获取早期诊断的依据[J].医学信息,2014(26):92-93.DOI:10.3969/j.issn.1006-1959.2014.26.094.
[4]Subedi K S,Takahashi T,Yamano T,et al.Usefulness of double dose contrast-enhanced magnetic resonance imaging for clear delineation of gross tumor volume in stereotactic radiotherapy treatment planning of metastatic brain tumors:a dose comparison study[J].J Radiat Res,2013,54(1):135-139.DOI:10.1093/jrr/rrs053.
[5]刘胜国,彭建,姚文勇.脑肿瘤卒中误诊的原因分析[J].中国肿瘤临床与康复,2015,22(8):545-546.
[6]孟晓峰.脑肿瘤卒中患者的手术治疗分析[J].中国医药指南,2015,13(26):157.
[7]马付勇.脑肿瘤卒中临床诊治分析[J].泰山医学院学报,2013,34(1):17-19.DOI:10.3969/j.issn.1004-7115.2013.01.006.
[8]Ilica A T,Rodrigues F,Maluf F,et al.Organizing hematoma mimicking brain tumor[J].Clin Imaging,2013,37(1):143-146.DOI:10.1016/j.clinimag.2012.04.006.
[9]张燃.手术治疗在出血性脑肿瘤卒中的临床应用研究[J].中外健康文摘,2012,9(18):106-107.DOI:10.3969/j.issn.1672-5085.2012.18.089.
[10]李宗平,游潮,钟琪,等.综合性卒中单元在出血性脑卒中术后患者中的应用研究[J].华西医学,2015(11):2019-2022.DOI:10.7507/1002-0179.20150576.
[11]熊海洋,吴中亚,周相军.急性出血性脑卒中起病的脑转移瘤临床特点分析[J].医药与保健,2015(3):10-11.
[12]Bauer S,May C,Dionysiou D,et al.Multiscale modeling for image analysis of brain tumor studies[J].IEEE Trans Biomed Eng,2012,59(1):25-29.DOI:10.1109/TBME.2011.2163406.
[13]李坪.出血性瘤卒中的临床诊断及治疗体会[J].医药前沿,2014,3(33):229.DOI:10.3969/j.issn.2095-1752.2014.33.223.
[14]陈韶青.脑肿瘤卒中误诊为脑出血临床分析[J].吉林医学,2014,56(23):5167-5168.
[15]孙锐.手术治疗脑肿瘤出血的临床效果及临床特点分析[J].世界最新医学信息文摘,2016,16(13):94-96.DOI:10.3969/j.issn.1671-3141.2016.13.069.
[16]Tustison N J,Shrinidhi K L,Wintermark M,et al.Optimal symmetric multimodal templates and concatenated random forests for supervised brain tumor segmentation(Simplified)with ANTs R[J].Neuroinformatics,2015,13(2):209-225.DOI:10.1007/s12021-014-9245-2.
[17]Loizou C P,Murray V,Pattichis M S,et al.Despeckle filtering for multiscale amplitude-modulation frequencymodulation(AM-FM)texture Analysis of ultrasound images of the intima-media complex[J].Int J Biomed Imaging,2014(2014):518414.DOI:10.1155/2014/518414.