乳腺钼钯、超声弹性成像与MRI临床用于诊断乳腺癌的对比分析
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摘要
目的研究乳腺钼靶、超声弹性成像以及磁核共振(MRI)对乳腺癌的临床诊断价值。方法方便选取2016年9月—2018年5月期间该院收治65例疑似乳腺癌的患者作为研究对象。所有患者均进行乳腺钼靶、超声弹性成像以及MRI检查,分析3种检查方式对乳腺癌的临床诊断价值。结果 65例患者中病理检查发现乳腺癌患者49例(75.38%),其中导管原位癌患者18例,黏液癌患者15例,腺样囊囊腺癌患者9例,髓样癌患者7例。其余16例均为良性肿瘤或肿块,占24.62%。乳腺钼靶以及超声弹性成像对乳腺癌诊断率分别为67.69%、69.23%,MRI诊断率为58.46%,乳腺钼靶及超声弹性成像对乳腺癌诊断率略高于MRI,差异有统计学意义(P<0.05)。乳腺钼靶和超声弹性成像诊断乳腺癌的诊断效能均差异无统计学意义(P>0.05);乳腺钼靶和超声弹性成像对乳腺癌特异度及阳性预测值均高于MRI,差异有统计学意义(P<0.05)。结论乳腺钼靶及超声弹性成像对乳腺癌诊断价值高于MRI,但单一乳腺钼靶或超声弹性成像对乳腺癌的诊断率仍然较低,两者联合检查可能会提高乳腺癌的诊断准确率。
Objective To compare the diagnosis value of mammary gland molybdenum target, ultrasonic elastography and MRI(magnetic resonance imaging) in breast cancer. Methods A total of 65 suspected breast cancer patients checked from September 2016 to May 2018 in our hospital were convenient selected. The mammary gland molybdenum target, ultrasonic elastography and MRI were taken to analyze its diagnosis value. Results The pathological examination indicated 49 breast cancer cases(75.38%) including 18 ductal carcinoma in situ cases, 15 mucoid carcinoma cases, 9 adenoid cystic carcinoma cases and 7 medullary carcinoma cases. The remaining 16 cases were proved as benign tumor or neoplasm(24.62%). The diagnosis rate of breast cancer based on the mammary gland molybdenum target, ultrasonic elastography and MRI was67.69%, 69.23% and 58.46%, respectively. The diagnosis rate based on the mammary gland molybdenum target and ultrasonic elastography was higher than that based on MRI,the difference was statistically significant(P<0.05). The diagnosis efficiency based on the mammary gland molybdenum target and ultrasonic elastography was not significantly different(P >0.05). The diagnosis specificity and positive predictive value based on the mammary gland molybdenum target and ultrasonic elastography was higher than that based on MRI,the difference was statistically significant(P <0.05). Conclusion The mammary gland molybdenum target and ultrasonic elastography has a higher diagnosis value than MRI. However, the single mammary gland molybdenum target or ultrasonic elastography examination has an unfavorable diagnosis rate, which can be possibly improved by the combined examination mode.
Objective To compare the diagnosis value of mammary gland molybdenum target, ultrasonic elastography and MRI(magnetic resonance imaging) in breast cancer. Methods A total of 65 suspected breast cancer patients checked from September 2016 to May 2018 in our hospital were convenient selected. The mammary gland molybdenum target, ultrasonic elastography and MRI were taken to analyze its diagnosis value. Results The pathological examination indicated 49 breast cancer cases(75.38%) including 18 ductal carcinoma in situ cases, 15 mucoid carcinoma cases, 9 adenoid cystic carcinoma cases and 7 medullary carcinoma cases. The remaining 16 cases were proved as benign tumor or neoplasm(24.62%). The diagnosis rate of breast cancer based on the mammary gland molybdenum target, ultrasonic elastography and MRI was67.69%, 69.23% and 58.46%, respectively. The diagnosis rate based on the mammary gland molybdenum target and ultrasonic elastography was higher than that based on MRI,the difference was statistically significant(P<0.05). The diagnosis efficiency based on the mammary gland molybdenum target and ultrasonic elastography was not significantly different(P >0.05). The diagnosis specificity and positive predictive value based on the mammary gland molybdenum target and ultrasonic elastography was higher than that based on MRI,the difference was statistically significant(P <0.05). Conclusion The mammary gland molybdenum target and ultrasonic elastography has a higher diagnosis value than MRI. However, the single mammary gland molybdenum target or ultrasonic elastography examination has an unfavorable diagnosis rate, which can be possibly improved by the combined examination mode.
引文
[1]秦甫.乳腺钼钯、超声弹性成像与MRI临床用于诊断乳腺癌的随机对照分析[J].中国CT和MRI杂志,2016,14(1):66-68.
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[6]卢建明,周旭,柯青兰,等.MRI、钼钯及高频超声对乳腺癌诊断效能对比分析[J].宁夏医科大学学报,2016,38(5):584-586.
[7]刘巧珍,唐英杰,崔志利,等.160例早期乳腺癌患者高频超声与钼钯X线诊断结果分析[J].中国妇幼保健,2018,33(7):1617-1619.
[8]左建富,郭小飞,陈继红,等.多普勒彩超、钼钯X线及CT诊断乳腺癌的临床差异分析[J].临床合理用药杂志,2015,8(19):117-118.
[9]张玉萍.钼靶X线摄影与彩色多普勒超声检查联合应用对乳腺癌的诊断价值分析[J].实用医学影像杂志,2016,17(4):357-359.
[10] Cho B B, Moon M M, Chellan J R, et al.In Vitro\r, PET/MRI Diagnosis and Targeted Chemotherapy for Cancer Using Radiolabeled Nanoprobe:A Theragnostic Approach[J].Bulletin of the Korean Chemical Society, 2016, 37(6):886-892.
[11] Gong, Faming, Zhang. A dual ligand targeted nanoprobe with high MRI sensitivity for diagnosis of breast cancer[J].Chinese Journal of Polymer Science, 2014, 32(3):321-332.
[2]黄东琼,李全,张磊,等.乳腺癌的X线钼钯及CT特征对照研究[J].西部医学,2013,25(1):128-130,134.
[3]韦伟.核磁共振成像和超声对乳腺恶性病变诊断的对比研究[J].中华危重症医学杂志:电子版,2016,9(2):122-124.
[4]曾焕城,邱斯奇,黄文河,等.乳腺癌患者腋窝淋巴结转移状态的预测[J].国际肿瘤学杂志,2015,42(11):852-855.
[5]于学娟,任瑞美,柳善刚,等.扩散加权成像在乳腺癌诊断与治疗中的应用及进展[J].中华肿瘤杂志,2014,36(10):721-725.
[6]卢建明,周旭,柯青兰,等.MRI、钼钯及高频超声对乳腺癌诊断效能对比分析[J].宁夏医科大学学报,2016,38(5):584-586.
[7]刘巧珍,唐英杰,崔志利,等.160例早期乳腺癌患者高频超声与钼钯X线诊断结果分析[J].中国妇幼保健,2018,33(7):1617-1619.
[8]左建富,郭小飞,陈继红,等.多普勒彩超、钼钯X线及CT诊断乳腺癌的临床差异分析[J].临床合理用药杂志,2015,8(19):117-118.
[9]张玉萍.钼靶X线摄影与彩色多普勒超声检查联合应用对乳腺癌的诊断价值分析[J].实用医学影像杂志,2016,17(4):357-359.
[10] Cho B B, Moon M M, Chellan J R, et al.In Vitro\r, PET/MRI Diagnosis and Targeted Chemotherapy for Cancer Using Radiolabeled Nanoprobe:A Theragnostic Approach[J].Bulletin of the Korean Chemical Society, 2016, 37(6):886-892.
[11] Gong, Faming, Zhang. A dual ligand targeted nanoprobe with high MRI sensitivity for diagnosis of breast cancer[J].Chinese Journal of Polymer Science, 2014, 32(3):321-332.