角膜生物力学特性对不同屈光度塑形效力的影响
摘要
目的观察不同屈光度患者行角膜塑形术后1年的角膜生物力学特性及塑形效力各参数的相关性分析。方法观察2012年12月至2013年6月初次配戴角膜塑形镜患者52例,按屈光度分为高屈光度组(球镜度>-3.50D)和低屈光度组(球镜度≤-3. 50D)。所有患者均采用夜戴角膜塑形镜的配戴方式,观察两组患者配戴前与夜戴1晚、1周、1个月、3个月、6个月及1年的裸眼视力、屈光度(球镜)、角膜曲率(平坦K值)、角膜地形图、眼轴、角膜中央厚度、角膜生物力学的变化,以及角膜生物力学与相关观察指标的相关性分析。结果两组患者配戴前除屈光度、裸眼视力及眼轴差异有显著性(P=0.00),其余观察指标差异均无显著性(P>0.05)。结论低屈光度组患者配戴角膜塑形镜的角膜参数较高屈光度组更早趋于稳定,塑形效果优于高屈光度组。
引文
[1] Holden B, Sankaridurg P, Smith E,et al. Myopia, an underrated global challenge to vision:where the current data takes us on myopia control[J].Eye(Lond),2013,28(2):142-146.
[2] Whatham A, Zimmermann F, Martinez A, et al. Influence of accommodation on off-axis refractive errors in myopic eyes[J]. J Vis,2009, 9(3):1-13.
[3] He M, Zeng J, Liu Y, et al. Refractive error and visual impairment in urban children in southern China[J]. Invest Ophthalmol Vis Sci,2004,45(3):793-799.
[4] Cheung SW, Cho P, Chui WS, et al. Refractive error and visual acuity changes in orthokeratology patients[J]. Optom Vis Sci,2007,84(5):410-416.
[5] Mika RO, Morgan B, Cron M, et al. Safety and efficacy of overnight orthokeratology in myopic children[J]. Optometry, 2007,78(5):225-231.
[6] Walline JJ, Jones LA, Sinnott LT, et al. Corneal reshaping and myopia progression[J]. Br J Ophthalmol,2009,93(9):1181-1185.
[7] Low W, Dirani M, Gazzard G, et al. Family history, near work,outdoor activity, and myopia in Singapore Chinese preschool children[J]. BrJ Ophthalmol,2010,94(8):1012-1016.
[8] Rose KA, Morgan IG, Smith W, et al. Myopia, lifestyle, and schooling in students of Chinese ethnicity in Singapore and Sydney[J]. Arch Ophthalmol,2008,126(4):527-530.
[9] Guggenheim JA, Northstone K, Mcmahon G, et al. Time outdoors and physical activity as predictors of incident myopia in childhood:A prospective cohort study[J]. Invest Ophthalmol Vis Sci,2012,53(6):2856-2865.
[10] Smith E L, Ramamirtham R, Qiaogrider Y, et al. Effects of foveal ablation on emmetropization and form-deprivation myopia[J]. Invest Ophthalmol Vis Sci,2007,48(9):3914-3922.
[11] Mutti DO, Hayes JR, Mitchell GL, et al. Refractive error, axial length, and relative peripheral refractive error before and after the onset of myopia[J]. Invest Ophthalmol Vis Sci,2007,48(6):2510-2519.
[12] Charman WN, Mountford J, Atchison DA, et al. Peripheral refraction in orthokeratology patients[J]. Optom Vis Sci,2006,83(9):641-648.
[13] Queiros A, Gonzalezmeijome JM, Jorge J, et al. Peripheral refraction in myopic patients after Orthokeratology[J]. Optom Vis Sci,2010,87(5):323-329.
[14] Kang P, Swarbrick HA. Peripheral refraction in myopic children wearing orthokeratology and gas-permeable lenses[J]. Optom Vis Sci,2011,88(4):476-482.
[15] Cho P, Cheung S. Retardation of Myopia in Orthokeratology(ROMIO)Study:A 2-year randomized clinical trial[J]. Invest Ophthalmol Vis Sci,2012,53(11):7077-7085.
[16] Hiraoka T,Kakita T,Okamoto F, et al. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia:A 5-year follow-up study[J]. Invest Ophthalmol Vis Sci,2012, 53(7):3913-3919.
[17] Charm J, Cho P. High myopia-partial reduction ortho-k:a 2-year randomized study.[J]. Optom Vis Sci,2013,90(6):530-539.
[18] Charm J, Cho P. High myopia-partial reduction orthokeratology(HM-PRO):Study design[J]. Cont Lens Anterior Eye,2013,36(4):164-170.
[19] Luce DA. Determining in vivo biomechanical properties of the cornea with an ocular response analyzer[J]. J Cataract Refract Surg,2005,31(1):156-162.
[20] Yeh TN, Green HM, Zhou Y, et al. Short-term effects of overnight Orthokeratology on Corneal Epithelial Permeability and Biomechanical Properties[J]. Invest Ophthalmol Vis Sci,2013,54(6):3902-3911.
[2] Whatham A, Zimmermann F, Martinez A, et al. Influence of accommodation on off-axis refractive errors in myopic eyes[J]. J Vis,2009, 9(3):1-13.
[3] He M, Zeng J, Liu Y, et al. Refractive error and visual impairment in urban children in southern China[J]. Invest Ophthalmol Vis Sci,2004,45(3):793-799.
[4] Cheung SW, Cho P, Chui WS, et al. Refractive error and visual acuity changes in orthokeratology patients[J]. Optom Vis Sci,2007,84(5):410-416.
[5] Mika RO, Morgan B, Cron M, et al. Safety and efficacy of overnight orthokeratology in myopic children[J]. Optometry, 2007,78(5):225-231.
[6] Walline JJ, Jones LA, Sinnott LT, et al. Corneal reshaping and myopia progression[J]. Br J Ophthalmol,2009,93(9):1181-1185.
[7] Low W, Dirani M, Gazzard G, et al. Family history, near work,outdoor activity, and myopia in Singapore Chinese preschool children[J]. BrJ Ophthalmol,2010,94(8):1012-1016.
[8] Rose KA, Morgan IG, Smith W, et al. Myopia, lifestyle, and schooling in students of Chinese ethnicity in Singapore and Sydney[J]. Arch Ophthalmol,2008,126(4):527-530.
[9] Guggenheim JA, Northstone K, Mcmahon G, et al. Time outdoors and physical activity as predictors of incident myopia in childhood:A prospective cohort study[J]. Invest Ophthalmol Vis Sci,2012,53(6):2856-2865.
[10] Smith E L, Ramamirtham R, Qiaogrider Y, et al. Effects of foveal ablation on emmetropization and form-deprivation myopia[J]. Invest Ophthalmol Vis Sci,2007,48(9):3914-3922.
[11] Mutti DO, Hayes JR, Mitchell GL, et al. Refractive error, axial length, and relative peripheral refractive error before and after the onset of myopia[J]. Invest Ophthalmol Vis Sci,2007,48(6):2510-2519.
[12] Charman WN, Mountford J, Atchison DA, et al. Peripheral refraction in orthokeratology patients[J]. Optom Vis Sci,2006,83(9):641-648.
[13] Queiros A, Gonzalezmeijome JM, Jorge J, et al. Peripheral refraction in myopic patients after Orthokeratology[J]. Optom Vis Sci,2010,87(5):323-329.
[14] Kang P, Swarbrick HA. Peripheral refraction in myopic children wearing orthokeratology and gas-permeable lenses[J]. Optom Vis Sci,2011,88(4):476-482.
[15] Cho P, Cheung S. Retardation of Myopia in Orthokeratology(ROMIO)Study:A 2-year randomized clinical trial[J]. Invest Ophthalmol Vis Sci,2012,53(11):7077-7085.
[16] Hiraoka T,Kakita T,Okamoto F, et al. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia:A 5-year follow-up study[J]. Invest Ophthalmol Vis Sci,2012, 53(7):3913-3919.
[17] Charm J, Cho P. High myopia-partial reduction ortho-k:a 2-year randomized study.[J]. Optom Vis Sci,2013,90(6):530-539.
[18] Charm J, Cho P. High myopia-partial reduction orthokeratology(HM-PRO):Study design[J]. Cont Lens Anterior Eye,2013,36(4):164-170.
[19] Luce DA. Determining in vivo biomechanical properties of the cornea with an ocular response analyzer[J]. J Cataract Refract Surg,2005,31(1):156-162.
[20] Yeh TN, Green HM, Zhou Y, et al. Short-term effects of overnight Orthokeratology on Corneal Epithelial Permeability and Biomechanical Properties[J]. Invest Ophthalmol Vis Sci,2013,54(6):3902-3911.