电针肾俞、次髎穴改善膀胱过度活动症患者生活质量的临床研究
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摘要
观察电针肾俞、次髎穴改善膀胱过度活动症患者生活质量的临床疗效,为膀胱过度活动症(OAB)的治疗提供一种疗效显著、操作简单、患者受益最大的治疗方法。方法将40例膀胱过度活动症患者随机分为治疗组与对照组,各20例。治疗组采用电针肾俞穴、次髎穴治疗,对照组采用针刺关元、中极、膀胱俞、三阴交、肾俞治疗,疗程均为4周(针灸1次/d,每周休息1 d)。比较治疗前后膀胱过度活动症症状评分量表(OABSS)评分、24 h排尿次数、尿垫称重重量及膀胱过度活动症问卷简表(OAB-QSF)评分等。结果治疗后,两组OABSS评分、24 h排尿次数、尿垫称重重量及膀胱过度活动症问卷简表(OAB-QSF)评分比较差异均有统计学意义(P<0.05),治疗组疗效优于对照组。结论电针肾俞、次髎穴治疗OAB疗效显著,治疗组明显改善膀胱过度活动症患者的生活质量。
Objective To observe the clinical effects on the quality of life in the patients of the overactive bladder( OAB) treated with electroacupuncture( EA) at Shenshu( BL23) and Ciliao( BL32) so as to provide a significantly effective therapeutic methods with simple operation to the overactive bladder. Methods A total of 40 patients of overactive bladder were randomized into a treatment group and a control group,20 cases in each one. In the treatment group,EA was used at BL23 and BL32. In the control group,acupuncture was used at Guanyuan( CV4),Zhongji( CV3),Pangguangshu( BL28),Sanyinjiao( SP6) and Shenshu( BL23). The duration of treatment was 4 weeks( once a day,and 6 treatments a week). The score of OAB symptom assessment scale( OABSS),24 h urination time,the weight of urinal pad and the score of questionnaire form( OAB-QSF) were compared before and after treatment. Results After treatment,The differences were significant between the two groups in the OABSS scores,24 h urination time,the weight of urinal pad and the OAB-QSF scores( P < 0. 05). The effects in the treatment group were better than the control group. Conclusion The EA therapy at Shenshu( BL23) and Ciliao( BL32) achieves the significant effects on OAB. The improvements for the quality of life in the treatment group are more obvious in the patients of OAB.
Objective To observe the clinical effects on the quality of life in the patients of the overactive bladder( OAB) treated with electroacupuncture( EA) at Shenshu( BL23) and Ciliao( BL32) so as to provide a significantly effective therapeutic methods with simple operation to the overactive bladder. Methods A total of 40 patients of overactive bladder were randomized into a treatment group and a control group,20 cases in each one. In the treatment group,EA was used at BL23 and BL32. In the control group,acupuncture was used at Guanyuan( CV4),Zhongji( CV3),Pangguangshu( BL28),Sanyinjiao( SP6) and Shenshu( BL23). The duration of treatment was 4 weeks( once a day,and 6 treatments a week). The score of OAB symptom assessment scale( OABSS),24 h urination time,the weight of urinal pad and the score of questionnaire form( OAB-QSF) were compared before and after treatment. Results After treatment,The differences were significant between the two groups in the OABSS scores,24 h urination time,the weight of urinal pad and the OAB-QSF scores( P < 0. 05). The effects in the treatment group were better than the control group. Conclusion The EA therapy at Shenshu( BL23) and Ciliao( BL32) achieves the significant effects on OAB. The improvements for the quality of life in the treatment group are more obvious in the patients of OAB.
引文
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[12]周惠芬,沈广澍,尹鑫,等.应用CT三维重建技术对290例骶后孔(八髎穴)变异性的研究[J].针刺研究,2016,41(4):361-364.
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[14]刘茁,田晓军,马潞林,等.骶神经刺激治疗难治性膀胱过度活动症9例报告[J].中国微创外科杂志,2017,17(4):322-328.
[15]沈周俊,张祥,邵远.膀胱过度活动症的治疗新进展[J].现代泌尿外科杂志,2014,19(10):640-643.
[2]Abrams P,Artibani W,Cardozo L,et al.Reviewing the ICS 2002 terminology report:the ongoing debate[J].Neurourol Urodyn,2009,28(4):287.
[3]Pagoria D,O'Connor RC,Guralnick ML.Antimuscarinic drugs:review of the cognitive impact when used to treat overactive bladder in elderly patients[J].Curr Urol Rep,2011,12(5):351-357.
[4]Leone RMU,Salvatore S,Alessandri F,et al.Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females[J].Expert Opin Drug Metab Toxicol,2012,8(11):1387-1408.
[5]Kajiwara M,Inoue K,Kato M,et al.Nocturnal enuresis and overactive bladder in children:an epidemiological study[J].Int J Urol,2006,13(1):36-41.
[6]高红英,吴玉斌.膀胱过度活动症诊治进展[J].实用儿科杂志,2016,31(5):379-385.
[7]Wang Y,Xu K,Hu H,et al.Prevalence,risk factors,andimpact on health related quality of life of overactive bladder inChina[J].Neurourol Urodyn,2011,30(8):1448-1455.
[8]颜明根,马小兵.膀胱过度活动症诊疗的研究进展[J].海军医学杂志,2011,32(4):276-281.
[9]Plotnikov EY,Pulkova NV,Pevzner IB,et al.Inflammatory preconditioning of mesenchymal multipotentstromal cells improves their immunomodulatory potency in acute pyelonephritis in rats[J].Cytotherapy,2013,15(6):679-689.
[10]那彦群.中国泌尿外科疾病诊断治疗指南(2014版)[M].北京:人民卫生出版社,2014:330-331.
[11]许能贵.经络腧穴学[M].北京:人民卫生出版社,2016:134-135.
[12]周惠芬,沈广澍,尹鑫,等.应用CT三维重建技术对290例骶后孔(八髎穴)变异性的研究[J].针刺研究,2016,41(4):361-364.
[13]周惠芬,丁曙晴,丁义江,等.八髎穴(骶后孔)定位、测量与取穴方法研究[J].中国针灸,2013,33(8):703-707.
[14]刘茁,田晓军,马潞林,等.骶神经刺激治疗难治性膀胱过度活动症9例报告[J].中国微创外科杂志,2017,17(4):322-328.
[15]沈周俊,张祥,邵远.膀胱过度活动症的治疗新进展[J].现代泌尿外科杂志,2014,19(10):640-643.