结节伴空洞表现的肺霍奇金淋巴瘤1例伴文献复习
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摘要
目的探讨结节伴空洞表现的肺霍奇金淋巴瘤的诊断。方法对2017年解放军总医院收治的1例CT表现为结节伴空洞的肺霍奇金淋巴瘤病例进行回顾并复习文献。结果患者女性,18岁,以左颈部淋巴结肿大、腰痛起病,CT示双肺多发大小不等结节,其内有空洞,病理诊断为经典型霍奇金淋巴瘤,结节硬化型。结论肺部影像表现为结节伴空洞时应警惕肺淋巴瘤。
Objective To explore the diagnosis of pulmonary Hodgkin lymphoma presenting as nodules and cavities. Methods Clinical data about one patient with pulmonary Hodgkin lymphoma presenting as nodules and cavities were retrospectively analyzed and related literatures were reviewed. Results A female, 18 years old, initially presented with swollen lymphnodes of left neck and backache. CT imaging showed nodules and cavities in bilateral lungs. The final pathological diagnosis was nodular sclerosing classical Hodgkin lymphoma. Conclusion Pulmonary lymphoma should be considered when the lung imaging shows nodules and cavities.
Objective To explore the diagnosis of pulmonary Hodgkin lymphoma presenting as nodules and cavities. Methods Clinical data about one patient with pulmonary Hodgkin lymphoma presenting as nodules and cavities were retrospectively analyzed and related literatures were reviewed. Results A female, 18 years old, initially presented with swollen lymphnodes of left neck and backache. CT imaging showed nodules and cavities in bilateral lungs. The final pathological diagnosis was nodular sclerosing classical Hodgkin lymphoma. Conclusion Pulmonary lymphoma should be considered when the lung imaging shows nodules and cavities.
引文
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2 万文丽,田磊,王晶,等.62例霍奇金淋巴瘤患者临床特征与预后分析[J].中华血液学杂志,2013,34(7):618-621.
3 李艳芬,赵瑜,薄剑,等.30例结外病变霍奇金淋巴瘤的临床分析[J].中国实验血液学杂志,2016,24(3):712-716.
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13 牛晓婷,胡红,高杰,等.原发性及继发性肺淋巴瘤40例临床分析[J].中华结核和呼吸杂志,2014,37(7):502-506.
14 霍真,李霁,刘鸿瑞,等.北京协和医院对18年间病理诊断肺淋巴瘤患者的回顾分析[J].中华肺部疾病杂志(电子版),2016,9(6):600-603.
15 Sklair-Levy M,Amir G,Spectre G,et al.Image-guided cuttingedge-needle biopsy of peripheral lymph nodes and superficial masses for the diagnosis of lymphoma[J].J Comput Assist Tomogr,2005,29(3):369-372.
16 白信花,郝彦勇,孙岩,等.肺霍奇金淋巴瘤临床病理分析[J].中国实验诊断学,2015,19(4):684-685.
17 Vanden Eynden F,Fadel E,de Perrot M,et al.Role of surgery in the treatment of primary pulmonary B-cell lymphoma[J].Ann Thorac Surg,2007,83(1):236-240.
2 万文丽,田磊,王晶,等.62例霍奇金淋巴瘤患者临床特征与预后分析[J].中华血液学杂志,2013,34(7):618-621.
3 李艳芬,赵瑜,薄剑,等.30例结外病变霍奇金淋巴瘤的临床分析[J].中国实验血液学杂志,2016,24(3):712-716.
4 Baccari-Ezzine S,Bouzaidi K,Chelbi E,et al.Unusual radiologic and histologic manifestations of primary pulmonary lymphoma[J].Asian Cardiovasc Thorac Ann,2014,22(3):362-364.
5 Urasinski T,Kamienska E,Gawlikowska-Sroka A,et al.Pediatric pulmonary Hodgkin lymphoma:analysis of 10 years data from a single center[J].Eur J Med Res,2010,15(Suppl 2):206-210.
6 Al-Osail AM,Al-Saif HS,Al-Hajri MM,et al.Hodgkin's Lymphoma as a Multiloculated Lung Cavity Lesion[J].Gulf J Oncolog,2017,1(24):61-65.
7 William J,Variakojis D,Yeldandi A,et al.Lymphoproliferative neoplasms of the lung:a review[J].Arch Pathol Lab Med,2013,137(3):382-391.
8 Li G,Hansmann ML,Zwingers T,et al.Primary lymphomas of the lung:morphological,immunohistochemical and clinical features[J].Histopathology,1990,16(6):519-531.
9 Cordier JF,Chailleux E,Lauque D,et al.Primary pulmonary lymphomas.A clinical study of 70 cases in nonimmunocompromised patients[J].Chest,1993,103(1):201-208.
10 Mc Elnay PJ,Pawade J,Chandratreya L,et al.Giant thoracic mass:an unusual presentation of primary pulmonary Hodgkin's lymphoma[J].BMJ Case Rep,2013:bcr2013200909.
11 张定培.肺部空洞病变的螺旋CT诊断[J].临床肺科杂志,2013,18(10):1926-1928.
12 王晓梅,王靖红,吴重重,等.以肺内病变为首发症状的淋巴瘤多层螺旋CT与PET/CT表现[J].中国医学影像学杂志,2015,23(9):677-681.
13 牛晓婷,胡红,高杰,等.原发性及继发性肺淋巴瘤40例临床分析[J].中华结核和呼吸杂志,2014,37(7):502-506.
14 霍真,李霁,刘鸿瑞,等.北京协和医院对18年间病理诊断肺淋巴瘤患者的回顾分析[J].中华肺部疾病杂志(电子版),2016,9(6):600-603.
15 Sklair-Levy M,Amir G,Spectre G,et al.Image-guided cuttingedge-needle biopsy of peripheral lymph nodes and superficial masses for the diagnosis of lymphoma[J].J Comput Assist Tomogr,2005,29(3):369-372.
16 白信花,郝彦勇,孙岩,等.肺霍奇金淋巴瘤临床病理分析[J].中国实验诊断学,2015,19(4):684-685.
17 Vanden Eynden F,Fadel E,de Perrot M,et al.Role of surgery in the treatment of primary pulmonary B-cell lymphoma[J].Ann Thorac Surg,2007,83(1):236-240.