补肾促排方治疗多囊卵巢综合征排卵障碍性不孕的临床研究
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摘要
目的观察补肾促排方治疗多囊卵巢综合征排卵障碍性不孕患者的临床效果。方法选取2016年6月—2018年6月妇科收治的多囊卵巢综合征排卵障碍性不孕患者80例;分为对照组与观察组各40例。对照组采用口服克罗米芬进行治疗,观察组采用补肾促排方进行治疗。对比分析2组患者的治疗效果、治疗前后血清性激素变化等相关指标。结果观察组患者总有效率95.0%(38/40),明显高于对照组70.0%(28/40),(P<0.05);LH、FSH、T、INS、E2、PRL等指标优于对照组(P<0.05)。结论补肾促排方治疗多囊卵巢综合征排卵障碍性不孕患者,可有效改善性激素水平,具有良好的治疗效果,值得临床推广应用。
Objective To observe the clinical effect of tonifying kidney and promoting ovulation recipe in treating polycystic ovarian syndrome with ovulation disorder infertility. Methods Eighty patients with polycystic ovary syndrome ovulation disorder infertility admitted to our hospital from June 2016 to June 1818 were enrolled in this study. They were divided into control group and observation group, with 40 patients in each group. The patients in the control group were treated with oral clomiphene citrate. 40 patients in the observation group were treated with tonifying kidney and promoting ovulation recipe. The therapeutic effects of the two groups of patients and the changes of serum sex hormones before and after treatment were compared. Results The total effective rate of the observation group was 95.0%, which was significantly higher than that of the control group(70.0%).(P<0.05) The difference was statistically significant. The LH, FSH, T, INS, E2, PRL and other indicators in the observation group were better than the control group(P<0.05), and the difference was statistically significant. Conclusion The tonifying kidney and promoting ovulation recipe in the treatment of patients with ovarian syndrome ovulation disorder infertility has a good therapeutic effect and effectively improves the level of sex hormones, which is worthy of clinical application.
Objective To observe the clinical effect of tonifying kidney and promoting ovulation recipe in treating polycystic ovarian syndrome with ovulation disorder infertility. Methods Eighty patients with polycystic ovary syndrome ovulation disorder infertility admitted to our hospital from June 2016 to June 1818 were enrolled in this study. They were divided into control group and observation group, with 40 patients in each group. The patients in the control group were treated with oral clomiphene citrate. 40 patients in the observation group were treated with tonifying kidney and promoting ovulation recipe. The therapeutic effects of the two groups of patients and the changes of serum sex hormones before and after treatment were compared. Results The total effective rate of the observation group was 95.0%, which was significantly higher than that of the control group(70.0%).(P<0.05) The difference was statistically significant. The LH, FSH, T, INS, E2, PRL and other indicators in the observation group were better than the control group(P<0.05), and the difference was statistically significant. Conclusion The tonifying kidney and promoting ovulation recipe in the treatment of patients with ovarian syndrome ovulation disorder infertility has a good therapeutic effect and effectively improves the level of sex hormones, which is worthy of clinical application.
引文
[1]程芳,张慧俭,程龙.消囊调经方联合克罗米芬治疗多囊卵巢综合征临床研究[J].中医学报,2015,30(7):1027-1029.
[2]郭金峰,王建凤,孔祥顺,等.补肾活血中药治疗多囊卵巢综合征导致排卵障碍性不孕的临床研究[J].中外女性健康(下半月),2014,18(4):65,83.
[3]范晓迪,马堃,单婧,等.补肾活血类中药治疗排卵障碍性不孕的系统评价[J].中国中药杂志,2013,38(19):3382-3387.
[4]刘艺,谈勇.从补肾活血法论治多囊卵巢综合征的研究进展[J].医学综述,2014,20(22):4163-4164.
[5] Nam H,Kim C H,Cha M Y,et al. Polycystic ovary syndrome woman with heterozygous androgen receptor gene mutation who gave birth to a child with androgen insensitivity syndrome[J]. Obstet Gynecol Sci,2015,58(2):179-182.
[6]李莹,刘芳.补肾活血祛痰方配合去氧孕烯炔雌醇片治疗不孕症的疗效观察[J].国际中医中药杂志,2014,36(1):54-55.
[7]金炫廷,马堃,单婧.补肾活血中药治疗多囊卵巢综合征导致排卵障碍性不孕的临床研究[J].中国中药杂志,2014,39(1):140-143.
[2]郭金峰,王建凤,孔祥顺,等.补肾活血中药治疗多囊卵巢综合征导致排卵障碍性不孕的临床研究[J].中外女性健康(下半月),2014,18(4):65,83.
[3]范晓迪,马堃,单婧,等.补肾活血类中药治疗排卵障碍性不孕的系统评价[J].中国中药杂志,2013,38(19):3382-3387.
[4]刘艺,谈勇.从补肾活血法论治多囊卵巢综合征的研究进展[J].医学综述,2014,20(22):4163-4164.
[5] Nam H,Kim C H,Cha M Y,et al. Polycystic ovary syndrome woman with heterozygous androgen receptor gene mutation who gave birth to a child with androgen insensitivity syndrome[J]. Obstet Gynecol Sci,2015,58(2):179-182.
[6]李莹,刘芳.补肾活血祛痰方配合去氧孕烯炔雌醇片治疗不孕症的疗效观察[J].国际中医中药杂志,2014,36(1):54-55.
[7]金炫廷,马堃,单婧.补肾活血中药治疗多囊卵巢综合征导致排卵障碍性不孕的临床研究[J].中国中药杂志,2014,39(1):140-143.