残胃癌围手术期营养支持
摘要
<正>残胃癌(gastric stump cancer,GSC)最早的定义由Balfour于1922年提出,定义为胃或十二指肠良性疾病行胃部分切除术后5年以上的残胃发生的原发性胃癌[1]。手术仍然是治疗GSC的有效措施,但是手术会带来很大创伤,加上GSC病人吸收障碍的存在,病人极易出现营养不良的问题。术后营养不良影响病人免疫功能及术后恢复,且术后感染率升高。因此,围手术期营养支持可能有助于缓解
引文
[1]Balfour DC.Factors influencing the life expectancy of patients operated on for gastric ulcer.Ann Surg,1922,76(3):405-408.
[2]胡祥.残胃复发癌治疗策略.中国实用外科杂志,2015,35(10):1075-1078.
[3]Firat O,Guler A,Sozbilen M,et al.Gastric remnant cancer:an old problem with novel concerns.Langenbecks Arch Surg,2009,394(1):93-97.
[4]Ahn HS,Kim JW,Yoo MW,et al.Clinicopathological features and surgical outcomes of patients with remnant gastric cancer after a distal gastrectomy.Ann Surg Oncol,2008,15(6):1632-1639.
[5]Sinning C,Schaefer N,Standop J,et al.Gastric stump carcinomaepidemiology and current concepts in pathogenesis and treatment.Eur J Surg Oncol,2007,33(2):133-139.
[6]Ohashi M,Katai H,Fukagawa T,et al.Cancer of the gastric stump following distal gastrectomy for cancer.Br J Surg,2007,94(1):92-95.
[7]Gurzu S,Copotoiu C,Azamfirei L,et al.A Caliber Persistent Artery(Dieulafoy's Lesion)which is Associated with an EarlyStage Gastric Stump Cancer Following a Distal Gastrectomy.J Clin Diagn Res,2013,7(8):1717-1719.
[8]Guzzo JL,Duncan M,Bass BL,et al.Severe and refractory peptic ulcer disease:the diagnostic dilemma:case report and comprehensive review.Dig Dis Sci,2005,50(11):1999-2008.
[9]An JY,Choi MG,Noh JH,et al.The outcome of patients with remnant primary gastric cancer compared with those having upper one-third gastric cancer.Am J Surg,2007,194(2):143-147.
[10]Tokunaga M,Sano T,Ohyama S,et al.Clinicopathological characteristics and survival difference between gastric stump carcinoma and primary upper third gastric cancer.J Gastrointest Surg,2013,17(2):313-318.
[11]Safatle-Ribeiro AV,Ribeiro U Jr,Reynolds JC.Gastric stump cancer:what is the risk.Dig Dis,1998,16(3):159-168.
[12]Kondo K.Duodenogastric reflux and gastric stump carcinoma.Gastric Cancer,2002,5(1):16-22.
[13]Watt PC,Sloan JM,Donaldson JD,et al.Relationship between histology and gastric juice p H and nitrite in the stomach after operation for duodenal ulcer.Gut,1984,25(3):246-252.
[14]Kopański Z,Brandys J,Piekoszewski W,et al.The bacterial flora and the changes of the N-nitrosamine concentration in the operated stomach.Przegl Lek,2001,58(4):348-350.
[15]Yamamoto N,Tokunaga M,Uemura Y,et al.Epstein-Barr virus and gastric remnant cancer,Cancer,1994,74(3):805-809.
[16]van Rees BP,Caspers E,zur Hausen A,et al.Different pattern of allelic loss in Epstein-Barr virus-positive gastric cancer with emphasis on the p53 tumor suppressor pathway.Am J Pathol,2002,161(4):1207-1213.
[17]Sitarz R,de Leng WW,Polak M,et al.IL-1B-31T>C promoter polymorphism is associated with gastric stump cancer but not with early onset or conventional gastric cancers.Virchows Arch,2008,453(3):249-255.
[18]刘梦静,姜葵,王邦茂.胃黏膜肠上皮化生的研究进展.国际消化病杂志,2017,37(02):73-76.
[19]Tsuei J,Chau T,Mills D,et al.Bile acid dysregulation,gut dysbiosis,and gastrointestinal cancer.Exp Biol Med(Maywood),2014,239(11):1489-1504.
[20]Li F,Zhang R,Liang H,et al.A retrospective clinicopathologic study of remnant gastric cancer after distal gastrectomy.Am J Clin Oncol,2013,36(3):244-249.
[21]Van Cutsem E,Arends J.The causes and consequences of cancerassociated malnutrition.Eur J Oncol Nurs,2005,9 Suppl 2:S51-S63.
[22]Weimann A,Braga M,Harsanyi L,et al.ESPEN Guidelines on Enteral Nutrition:Surgery including organ transplantation.Clin Nutr,2006,25(2):224-244.
[23]Bozzetti F,Arends J,Lundholm K,et al.ESPEN Guidelines on Parenteral Nutrition:non-surgical oncology.Clin Nutr,2009,28(4):445-454.
[24]Dreesen M,Foulon V,Spriet I,et al.Epidemiology of catheterrelated infections in adult patients receiving home parenteral nutrition:a systematic review.Clin Nutr,2013,32(1):16-26.
[25]KELLY WD,MACLEAN LD,PERRY JF,et al.A study of patients following total and near-total gastrectomy.Surgery,1954,35(6):964-982.
[26]Zhou X,Xu L,Huang Z,et al.The hematologic markers as prognostic factors in patients with resectable gastric cancer.Cancer Biomark,2016,17(3):359-367.
[27]Imamura T,Komatsu S,Ichikawa D,et al.Reconstruction method as an independent risk factor for the postoperative decrease in hemoglobin in stage I gastric cancer.J Gastroenterol Hepatol,2016,31(5):959-964.
[28]Kim H I,Hyung W J,Song K J,et al.OrB 1 2replacement:an effective treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients.Ann Surg Oncol,2011,18(13):3711-3717.
[29]Miranti EH,Stolzenberg-Solomon R,Weinstein SJ,et al.Low vitamin B12 increases risk of gastric cancer:A prospective study of one-carbon metabolism nutrients and risk of upper gastrointestinal tract cancer.Int J Cancer,2017,141(6):1120-1129.
[30]Kruizenga HM,Seidell JC,de Vet HC,et al.Development and validation of a hospital screening tool for malnutrition:the short nutritional assessment questionnaire(SNAQ).Clin Nutr,2005,24(1):75-82.
[31]van Venrooij LM,van Leeuwen PA,Hopmans W,et al.Accuracy of quick and easy undernutrition screening tools--Short Nutritional Assessment Questionnaire,Malnutrition Universal Screening Tool,and modified Malnutrition Universal Screening Tool--in patients undergoing cardiac surgery.J Am Diet Assoc,2011,111(12):1924-1930.
[32]Tegels JJ,de Maat MF,HulsewéKW,et al.Value of geriatric frailty and nutritional status assessment in predicting postoperative mortality in gastric cancer surgery.J Gastrointest Surg,2014,18(3):439-445;discussion 445-446.
[33]Asher V,Lee J,Innamaa A,et al.Preoperative platelet lymphocyte ratio as an independent prognostic marker in ovarian cancer.Clin Transl Oncol,2011,13(7):499-503.
[34]Nozoe T,Ninomiya M,Maeda T,et al.Prognostic nutritional index:a tool to predict the biological aggressiveness of gastric carcinoma.Surg Today,2010,40(5):440-443.
[35]Sakurai K,Ohira M,Tamura T,et al.Predictive Potential of Preoperative Nutritional Status in Long-Term Outcome Projections for Patients with Gastric Cancer.Ann Surg Oncol,2016,23(2):525-533.
[36]Kuzu MA,Terzio?lu H,Gen?V,et al.Preoperative nutritional risk assessment in predicting postoperative outcome in patients undergoing major surgery.World J Surg,2006,30(3):378-390.
[37]Arends J,Bodoky G,Bozzetti F,et al.ESPEN Guidelines on Enteral Nutrition:Non-surgical oncology.Clin Nutr,2006,25(2):245-259.
[38]Mariette C,De Botton ML,Piessen G.Surgery in esophageal and gastric cancer patients:what is the role for nutrition support in your daily practice.Ann Surg Oncol,2012,19(7):2128-2134.
[39]Ding D,Feng Y,Song B,et al.Effects of preoperative and postoperative enteral nutrition on postoperative nutritional status and immune function of gastric cancer patients.Turk J Gastroenterol,2015,26(2):181-185.
[40]Heyland DK,Novak F,Drover JW,et al.Should immunonutrition become routine in critically ill patients?A systematic review of the evidence.JAMA,2001,286(8):944-953.
[41]Cerantola Y,Hübner M,Grass F,et al.Immunonutrition in gastrointestinal surgery.Br J Surg,2011,98(1):37-48.
[42]Gianotti L,Braga M,Nespoli L,et al.A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer.Gastroenterology,2002,122(7):1763-1770.
[43]Bilici A,Sonkaya A,Ercan S,et al.The changing of serum vitamin B12 and homocysteine levels after gastrectomy in patients with gastric cancer:do they associate with clinicopathological factors.Tumour Biol,2015,36(2):823-828.
[44]Xiao Q,Freedman ND,Ren J,et al.Intakes of folate,methionine,vitamin B6,and vitamin B12 with risk of esophageal and gastric cancer in a large cohort study.Br J Cancer,2014,110(5):1328-1333.
[45]Sch?fer T,Bauer CP,Beyer K,et al.S3-Guideline on allergy prevention:2014 update:Guideline of the German Society for Allergology and Clinical Immunology(DGAKI)and the German Society for Pediatric and Adolescent Medicine(DGKJ).Allergo J Int,2014,23(6):186-199.
[46]Shim H,Cheong JH,Lee KY,et al.Perioperative nutritional status changes in gastrointestinal cancer patients.Yonsei Med J,2013,54(6):1370-1376.
[47]Gabor S,Renner H,Matzi V,et al.Early enteral feeding compared with parenteral nutrition after oesophageal or oesophagogastric resection and reconstruction.Br J Nutr,2005,93(4):509-513.
[48]Huang D,Sun Z,Huang J,et al.Early enteral nutrition in combination with parenteral nutrition in elderly patients after surgery due to gastrointestinal cancer.Int J Clin Exp Med,2015,8(8):13937-13945.
[49]Wu GH,Liu ZH,Wu ZH,et al.Perioperative artificial nutrition in malnourished gastrointestinal cancer patients.World J Gastroenterol,2006,12(15):2441-2444.
[50]Arends J,Bachmann P,Baracos V,et al.ESPEN guidelines on nutrition in cancer patients.Clin Nutr,2017,36(1):11-48.
[2]胡祥.残胃复发癌治疗策略.中国实用外科杂志,2015,35(10):1075-1078.
[3]Firat O,Guler A,Sozbilen M,et al.Gastric remnant cancer:an old problem with novel concerns.Langenbecks Arch Surg,2009,394(1):93-97.
[4]Ahn HS,Kim JW,Yoo MW,et al.Clinicopathological features and surgical outcomes of patients with remnant gastric cancer after a distal gastrectomy.Ann Surg Oncol,2008,15(6):1632-1639.
[5]Sinning C,Schaefer N,Standop J,et al.Gastric stump carcinomaepidemiology and current concepts in pathogenesis and treatment.Eur J Surg Oncol,2007,33(2):133-139.
[6]Ohashi M,Katai H,Fukagawa T,et al.Cancer of the gastric stump following distal gastrectomy for cancer.Br J Surg,2007,94(1):92-95.
[7]Gurzu S,Copotoiu C,Azamfirei L,et al.A Caliber Persistent Artery(Dieulafoy's Lesion)which is Associated with an EarlyStage Gastric Stump Cancer Following a Distal Gastrectomy.J Clin Diagn Res,2013,7(8):1717-1719.
[8]Guzzo JL,Duncan M,Bass BL,et al.Severe and refractory peptic ulcer disease:the diagnostic dilemma:case report and comprehensive review.Dig Dis Sci,2005,50(11):1999-2008.
[9]An JY,Choi MG,Noh JH,et al.The outcome of patients with remnant primary gastric cancer compared with those having upper one-third gastric cancer.Am J Surg,2007,194(2):143-147.
[10]Tokunaga M,Sano T,Ohyama S,et al.Clinicopathological characteristics and survival difference between gastric stump carcinoma and primary upper third gastric cancer.J Gastrointest Surg,2013,17(2):313-318.
[11]Safatle-Ribeiro AV,Ribeiro U Jr,Reynolds JC.Gastric stump cancer:what is the risk.Dig Dis,1998,16(3):159-168.
[12]Kondo K.Duodenogastric reflux and gastric stump carcinoma.Gastric Cancer,2002,5(1):16-22.
[13]Watt PC,Sloan JM,Donaldson JD,et al.Relationship between histology and gastric juice p H and nitrite in the stomach after operation for duodenal ulcer.Gut,1984,25(3):246-252.
[14]Kopański Z,Brandys J,Piekoszewski W,et al.The bacterial flora and the changes of the N-nitrosamine concentration in the operated stomach.Przegl Lek,2001,58(4):348-350.
[15]Yamamoto N,Tokunaga M,Uemura Y,et al.Epstein-Barr virus and gastric remnant cancer,Cancer,1994,74(3):805-809.
[16]van Rees BP,Caspers E,zur Hausen A,et al.Different pattern of allelic loss in Epstein-Barr virus-positive gastric cancer with emphasis on the p53 tumor suppressor pathway.Am J Pathol,2002,161(4):1207-1213.
[17]Sitarz R,de Leng WW,Polak M,et al.IL-1B-31T>C promoter polymorphism is associated with gastric stump cancer but not with early onset or conventional gastric cancers.Virchows Arch,2008,453(3):249-255.
[18]刘梦静,姜葵,王邦茂.胃黏膜肠上皮化生的研究进展.国际消化病杂志,2017,37(02):73-76.
[19]Tsuei J,Chau T,Mills D,et al.Bile acid dysregulation,gut dysbiosis,and gastrointestinal cancer.Exp Biol Med(Maywood),2014,239(11):1489-1504.
[20]Li F,Zhang R,Liang H,et al.A retrospective clinicopathologic study of remnant gastric cancer after distal gastrectomy.Am J Clin Oncol,2013,36(3):244-249.
[21]Van Cutsem E,Arends J.The causes and consequences of cancerassociated malnutrition.Eur J Oncol Nurs,2005,9 Suppl 2:S51-S63.
[22]Weimann A,Braga M,Harsanyi L,et al.ESPEN Guidelines on Enteral Nutrition:Surgery including organ transplantation.Clin Nutr,2006,25(2):224-244.
[23]Bozzetti F,Arends J,Lundholm K,et al.ESPEN Guidelines on Parenteral Nutrition:non-surgical oncology.Clin Nutr,2009,28(4):445-454.
[24]Dreesen M,Foulon V,Spriet I,et al.Epidemiology of catheterrelated infections in adult patients receiving home parenteral nutrition:a systematic review.Clin Nutr,2013,32(1):16-26.
[25]KELLY WD,MACLEAN LD,PERRY JF,et al.A study of patients following total and near-total gastrectomy.Surgery,1954,35(6):964-982.
[26]Zhou X,Xu L,Huang Z,et al.The hematologic markers as prognostic factors in patients with resectable gastric cancer.Cancer Biomark,2016,17(3):359-367.
[27]Imamura T,Komatsu S,Ichikawa D,et al.Reconstruction method as an independent risk factor for the postoperative decrease in hemoglobin in stage I gastric cancer.J Gastroenterol Hepatol,2016,31(5):959-964.
[28]Kim H I,Hyung W J,Song K J,et al.OrB 1 2replacement:an effective treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients.Ann Surg Oncol,2011,18(13):3711-3717.
[29]Miranti EH,Stolzenberg-Solomon R,Weinstein SJ,et al.Low vitamin B12 increases risk of gastric cancer:A prospective study of one-carbon metabolism nutrients and risk of upper gastrointestinal tract cancer.Int J Cancer,2017,141(6):1120-1129.
[30]Kruizenga HM,Seidell JC,de Vet HC,et al.Development and validation of a hospital screening tool for malnutrition:the short nutritional assessment questionnaire(SNAQ).Clin Nutr,2005,24(1):75-82.
[31]van Venrooij LM,van Leeuwen PA,Hopmans W,et al.Accuracy of quick and easy undernutrition screening tools--Short Nutritional Assessment Questionnaire,Malnutrition Universal Screening Tool,and modified Malnutrition Universal Screening Tool--in patients undergoing cardiac surgery.J Am Diet Assoc,2011,111(12):1924-1930.
[32]Tegels JJ,de Maat MF,HulsewéKW,et al.Value of geriatric frailty and nutritional status assessment in predicting postoperative mortality in gastric cancer surgery.J Gastrointest Surg,2014,18(3):439-445;discussion 445-446.
[33]Asher V,Lee J,Innamaa A,et al.Preoperative platelet lymphocyte ratio as an independent prognostic marker in ovarian cancer.Clin Transl Oncol,2011,13(7):499-503.
[34]Nozoe T,Ninomiya M,Maeda T,et al.Prognostic nutritional index:a tool to predict the biological aggressiveness of gastric carcinoma.Surg Today,2010,40(5):440-443.
[35]Sakurai K,Ohira M,Tamura T,et al.Predictive Potential of Preoperative Nutritional Status in Long-Term Outcome Projections for Patients with Gastric Cancer.Ann Surg Oncol,2016,23(2):525-533.
[36]Kuzu MA,Terzio?lu H,Gen?V,et al.Preoperative nutritional risk assessment in predicting postoperative outcome in patients undergoing major surgery.World J Surg,2006,30(3):378-390.
[37]Arends J,Bodoky G,Bozzetti F,et al.ESPEN Guidelines on Enteral Nutrition:Non-surgical oncology.Clin Nutr,2006,25(2):245-259.
[38]Mariette C,De Botton ML,Piessen G.Surgery in esophageal and gastric cancer patients:what is the role for nutrition support in your daily practice.Ann Surg Oncol,2012,19(7):2128-2134.
[39]Ding D,Feng Y,Song B,et al.Effects of preoperative and postoperative enteral nutrition on postoperative nutritional status and immune function of gastric cancer patients.Turk J Gastroenterol,2015,26(2):181-185.
[40]Heyland DK,Novak F,Drover JW,et al.Should immunonutrition become routine in critically ill patients?A systematic review of the evidence.JAMA,2001,286(8):944-953.
[41]Cerantola Y,Hübner M,Grass F,et al.Immunonutrition in gastrointestinal surgery.Br J Surg,2011,98(1):37-48.
[42]Gianotti L,Braga M,Nespoli L,et al.A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer.Gastroenterology,2002,122(7):1763-1770.
[43]Bilici A,Sonkaya A,Ercan S,et al.The changing of serum vitamin B12 and homocysteine levels after gastrectomy in patients with gastric cancer:do they associate with clinicopathological factors.Tumour Biol,2015,36(2):823-828.
[44]Xiao Q,Freedman ND,Ren J,et al.Intakes of folate,methionine,vitamin B6,and vitamin B12 with risk of esophageal and gastric cancer in a large cohort study.Br J Cancer,2014,110(5):1328-1333.
[45]Sch?fer T,Bauer CP,Beyer K,et al.S3-Guideline on allergy prevention:2014 update:Guideline of the German Society for Allergology and Clinical Immunology(DGAKI)and the German Society for Pediatric and Adolescent Medicine(DGKJ).Allergo J Int,2014,23(6):186-199.
[46]Shim H,Cheong JH,Lee KY,et al.Perioperative nutritional status changes in gastrointestinal cancer patients.Yonsei Med J,2013,54(6):1370-1376.
[47]Gabor S,Renner H,Matzi V,et al.Early enteral feeding compared with parenteral nutrition after oesophageal or oesophagogastric resection and reconstruction.Br J Nutr,2005,93(4):509-513.
[48]Huang D,Sun Z,Huang J,et al.Early enteral nutrition in combination with parenteral nutrition in elderly patients after surgery due to gastrointestinal cancer.Int J Clin Exp Med,2015,8(8):13937-13945.
[49]Wu GH,Liu ZH,Wu ZH,et al.Perioperative artificial nutrition in malnourished gastrointestinal cancer patients.World J Gastroenterol,2006,12(15):2441-2444.
[50]Arends J,Bachmann P,Baracos V,et al.ESPEN guidelines on nutrition in cancer patients.Clin Nutr,2017,36(1):11-48.