摘要
目的:了解江门地区50岁以上老年性白内障患者结膜囊带菌状况,分析细菌构成和对药物的敏感性。方法:选择2016年6-10月在本院住院的50岁以上的老年性白内障患者707例1414眼,在结膜囊无菌化准备前,采集结膜囊标本做细菌培养及药敏试验。结果:送检1414份标本中,有菌生长106眼(7.5%),其中91眼(6.4%)有细菌生长,15眼(1.1%)有真菌生长。不同性别、眼别、年龄,结膜囊细菌检出率比较,差异均无统计学意义(P>0.05)。不同月份、不同居住地的结膜囊细菌检出率比较,差异均有统计学意义(P<0.05)。阳性标本中各菌种的构成比为,G~+球菌75.5%(80/106),G~+杆菌7.5%(8/106),G-~杆菌1.9%(2/106),G~-球菌0.9%(1/106),真菌14.2%(15/106)。药物敏感试验结果显示,大多数G~+球菌对克林霉素、妥布霉素、万古霉素敏感,对林可霉素和诺氟沙星耐药。整体而言,万古霉素、左氧氟沙星的耐药率较低。结论:江门地区50岁以上老年性白内障患者结膜囊可能带有病原菌,并以G~+球菌为主。大多数细菌对万古霉素和耐药的左氧氟沙星敏感。
Objective:To analyze the situation of conjunctival sac carrier in patients over 50 years old with senile cataract in the area of Jiangmen Method:A total of 707 patients of 1414 eyes with senile cataract aged over 50 years who admitted to our hospital from June to October in 2016 were selected. Before the preparation of conjunctival sac, specimens of conjunctival sac were collected for bacterial culture and drug sensitivity test.Result:Among 1414 pieces of inspected specimens, 106 eyes(7.5%) were bacterial growth.Among them, 91 eyes(6.4%) were bacterial growth bacteria and 15 eyes(1.1%) were fungal growth.There had no significant differences in the comparison regarding different sex,eyes,ages,and the detection rate of conjunctival sac bacteria(P>0.05).The bacterial detection rate of conjunctival sac in different months and different places were statistically significant(P<0.05).The constituent ratios of different bacteria in the positive samples were G+ cocci 75.5%(80/106),G~+ bacillus 7.5%(8/106),G~-bacillus 1.9%(2/106),G~-cocci 0.9%(1/106),and fungi 14.2%(15/106).It can be seen from the drug sensitivity test that most G~+ coccus was sensitive to Clindamycin,Tobramycin,and Vancomycin and most G~+ coccus was drug resistive to Lincomycin and Norfloxacin.Overall,the rates of drug resistance to Vancomycin and Levofloxacin were low.Conclusion:Pathogenic bacteria may be found in conjunctiva sacs among patients with senile catarace aged over 50 years in Jiangmeng District.The dominant bacteria are G~+ coccus.Most of bacterias are sensitive to Vancomycin and Levofloxacin.
引文
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