骨骼肌急性运动损伤机制探究
摘要
随着人们健康意识的提升,运动已经成为生活中重要的日常行为。但是随着运动人群的增加,运动损伤也居高不下。这些运动损伤大多是急性损伤,常见的有撕裂、挫伤、冷冻、灼烧等,而些运动损伤会影响人们的日常生活及健康。所以,本文主要采用了文献资料法介绍了急性运动损伤及机制。从理论上宏观阐述了急性运动损伤与机械力过大、拉伸的速度有关;微观上急性运动损伤是由于细胞膜的损伤及肌原纤维的损伤导致的。其目的在于为下一步的急性损伤预防与修复提供解决思路。
With the improvement of people's health awareness, sports have become an important daily behavior in life. However, with the increase of the sports population, acute sports injuries also remain high. These acute sports injuries are mostly acute injuries, the common ones are laceration, contusion, freezing, burning and so on. These sports injuries can affect People's Daily life and health. Therefore, this paper mainly introduces the acute sports injury and its mechanism by means of literature review. Theoretically, acute sports injury is caused by excessive mechanical force and the speed of stretching. Microscopically, acute sports injury is caused by cell membrane injury and myofibril injury. Its purpose is to provide a solution for the prevention and repair of acute injury in the next step.
With the improvement of people's health awareness, sports have become an important daily behavior in life. However, with the increase of the sports population, acute sports injuries also remain high. These acute sports injuries are mostly acute injuries, the common ones are laceration, contusion, freezing, burning and so on. These sports injuries can affect People's Daily life and health. Therefore, this paper mainly introduces the acute sports injury and its mechanism by means of literature review. Theoretically, acute sports injury is caused by excessive mechanical force and the speed of stretching. Microscopically, acute sports injury is caused by cell membrane injury and myofibril injury. Its purpose is to provide a solution for the prevention and repair of acute injury in the next step.
引文
[1]Tidball JG.Mechanisms of muscle injury,repair,and regeneration[J].Comprehensive Physiology,2011,1(4):2029-2062.
[2]贺强,漆正堂,丁树哲.骨骼肌的内分泌功能与运动代谢适应[J].中国运动医学杂志,2015,34(2):201-207.
[3]Gordon AM,Huxley AF,Julian FJ.The variation in isometric tension with sarcomere length in vertebrate muscle fibres[J].Journal of Physiology,1966,184(1):170-192.
[4]Lynch G S,Faulkner JA.Contraction-induced injury to single muscle fibers:Velocity of stretch does not influence the force deficit[J].A m JPhysiol,1998,275(1):1548-1554.
[5]Warren GL,O'Farrell L,Summan M,et al.Role of cc chemokines in skeletal muscle functional restoration after injury[J].Am J Physiol Cell Physiol,2004,286(5):C1031-C1036.
[6]Clarkson PM,Apple FS,Byrnes WC,et al.Creatine kinase isoforms following isometric exercise[J].Muscle&Nerve,2010,10(1):41-44.
[7]Kasper CE.Sarcolemmal disruption in reloaded atrophic skeletal muscle[J].Journal of Applied Physiology,1995,79(2):607-614.
[8]Komulainen J,Kyt LJ,Vihko V.Running-induced muscle injury and myocellular enzyme release in rats[J].Journal of Applied Physiology,1994,77(5):2299-2304.
[9]Fredsted A,Gissel H,Madsen K,et al.Causes of excitation-induced muscle cell damage in isometric contractions:Mechanical stress or calcium overload[J].Am J Physiol Regul Integr Comp Physiol,2007,292(6):2249-2258.
[10]Nelson WJ,Traub P.Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins[J].Molecular&Cellular Biology,1983,3(6):1146-1156.
[11]Reddy MK,Rabinowitz M,Zak R.Stringent requirement for ca2+in the removal of z-lines and alpha-actinin from isolated myofibrils by Ca2+-activated neutral proteinase[J].Biochemical Journal,1983,209(3):635-641.
[12]Fredrik Lauritzen,G Ran Paulsen,Truls Raastad,et al.Gross ultrastructural changes and necrotic fiber segments in elbow f lexor muscles after maximal voluntary eccentric action in humans[J].Journal of Applied Physiology,2009,107(6):1923-1934.
[2]贺强,漆正堂,丁树哲.骨骼肌的内分泌功能与运动代谢适应[J].中国运动医学杂志,2015,34(2):201-207.
[3]Gordon AM,Huxley AF,Julian FJ.The variation in isometric tension with sarcomere length in vertebrate muscle fibres[J].Journal of Physiology,1966,184(1):170-192.
[4]Lynch G S,Faulkner JA.Contraction-induced injury to single muscle fibers:Velocity of stretch does not influence the force deficit[J].A m JPhysiol,1998,275(1):1548-1554.
[5]Warren GL,O'Farrell L,Summan M,et al.Role of cc chemokines in skeletal muscle functional restoration after injury[J].Am J Physiol Cell Physiol,2004,286(5):C1031-C1036.
[6]Clarkson PM,Apple FS,Byrnes WC,et al.Creatine kinase isoforms following isometric exercise[J].Muscle&Nerve,2010,10(1):41-44.
[7]Kasper CE.Sarcolemmal disruption in reloaded atrophic skeletal muscle[J].Journal of Applied Physiology,1995,79(2):607-614.
[8]Komulainen J,Kyt LJ,Vihko V.Running-induced muscle injury and myocellular enzyme release in rats[J].Journal of Applied Physiology,1994,77(5):2299-2304.
[9]Fredsted A,Gissel H,Madsen K,et al.Causes of excitation-induced muscle cell damage in isometric contractions:Mechanical stress or calcium overload[J].Am J Physiol Regul Integr Comp Physiol,2007,292(6):2249-2258.
[10]Nelson WJ,Traub P.Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins[J].Molecular&Cellular Biology,1983,3(6):1146-1156.
[11]Reddy MK,Rabinowitz M,Zak R.Stringent requirement for ca2+in the removal of z-lines and alpha-actinin from isolated myofibrils by Ca2+-activated neutral proteinase[J].Biochemical Journal,1983,209(3):635-641.
[12]Fredrik Lauritzen,G Ran Paulsen,Truls Raastad,et al.Gross ultrastructural changes and necrotic fiber segments in elbow f lexor muscles after maximal voluntary eccentric action in humans[J].Journal of Applied Physiology,2009,107(6):1923-1934.