Conduit necrosis following esophagectomy: An up-to-date literature review
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  • 英文篇名:Conduit necrosis following esophagectomy: An up-to-date literature review
  • 作者:Antonios ; Athanasiou ; Mairead ; Hennessy ; Eleftherios ; Spartalis ; Benjamin ; H ; L ; Tan ; Ewen ; A ; Griffiths
  • 英文作者:Antonios Athanasiou;Mairead Hennessy;Eleftherios Spartalis;Benjamin H L Tan;Ewen A Griffiths;Department of Upper GI, Bariatric and Minimally Invasive Surgery, St.James' University Hospital, Leeds Teaching Hospitals NHS Trust;Department of Anaesthesia, University Hospital of Waterford;Laboratory of Experimental Surgery and Surgical Research, University of Athens, Medical School;Department of Upper Gastrointestinal Surgery, University Hospitals Birmingham NHS Foundation Trust;
  • 英文关键词:Esophagectomy;;Esophageal cancers;;Esophagogastric anastomosis
  • 中文刊名:WJGS
  • 英文刊名:世界胃肠外科杂志(电子版)(英文版)
  • 机构:Department of Upper GI, Bariatric and Minimally Invasive Surgery, St.James' University Hospital, Leeds Teaching Hospitals NHS Trust;Department of Anaesthesia, University Hospital of Waterford;Laboratory of Experimental Surgery and Surgical Research, University of Athens, Medical School;Department of Upper Gastrointestinal Surgery, University Hospitals Birmingham NHS Foundation Trust;
  • 出版日期:2019-03-27
  • 出版单位:World Journal of Gastrointestinal Surgery
  • 年:2019
  • 期:v.11
  • 语种:英文;
  • 页:WJGS201903005
  • 页数:14
  • CN:03
  • 分类号:42-55
摘要
Esophageal conduit ischaemia and necrosis is an uncommon but devastating complication of esophagectomy and remains one of the most challenging issues in surgical practice. The incidence, time interval to develop symptoms, and clinical presentation are highly variable with no predictable pattern. Evidence comes from case reports and case series rather than randomized controlled trials.We describe the issues surrounding conduit necrosis affecting the stomach,jejunum and colon as an esophageal replacement and the advantages,disadvantages and challenges of each type of reconstruction. Diagnosis is challenging for the most experienced surgeon. Upper gastrointestinal endoscopy and computed tomography thorax with both oral and intravenous contrast is the gold standard. Management, either conservative or interventional is also a difficult decision. Management options include conservative treatment and more aggressive treatments such as stent insertion, surgical debridement and repair of the esophagus using jejunum, colon or a musculocutaneous flap. In spite of recent advances in surgical techniques, there is no reliable strategy to manage esophageal conduit necrosis. Our review covers the pathophysiology and clinical significance of esophageal necrosis while highlighting current techniques of prevention, diagnosis and treatment of this life-threatening condition.
        Esophageal conduit ischaemia and necrosis is an uncommon but devastating complication of esophagectomy and remains one of the most challenging issues in surgical practice. The incidence, time interval to develop symptoms, and clinical presentation are highly variable with no predictable pattern. Evidence comes from case reports and case series rather than randomized controlled trials.We describe the issues surrounding conduit necrosis affecting the stomach,jejunum and colon as an esophageal replacement and the advantages,disadvantages and challenges of each type of reconstruction. Diagnosis is challenging for the most experienced surgeon. Upper gastrointestinal endoscopy and computed tomography thorax with both oral and intravenous contrast is the gold standard. Management, either conservative or interventional is also a difficult decision. Management options include conservative treatment and more aggressive treatments such as stent insertion, surgical debridement and repair of the esophagus using jejunum, colon or a musculocutaneous flap. In spite of recent advances in surgical techniques, there is no reliable strategy to manage esophageal conduit necrosis. Our review covers the pathophysiology and clinical significance of esophageal necrosis while highlighting current techniques of prevention, diagnosis and treatment of this life-threatening condition.
引文
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