复合型石墨氮化碳在生物荧光探针中的研究进展
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摘要
g-C_3N_4是一种由碳和氮原子组成的新兴发光材料,具有石墨相结构、独特的光学和电子特性。与纯g-C_3N_4材料相比,复合型g-C_3N_4具有更高的检测性能和更广泛的检测应用,在生物成像和生物检测等领域具有很大的发展前景。本文主要对复合型g-C_3N_4在检测重金属离子、人体内生物大分子、细胞成像等荧光探针方面的应用进行了综述,并对复合型g-C_3N_4在将来的发展应用进行了展望。
Graphite carbon nitride(g-C_3N_4)is a new type of optical material composed of carbon and nitrogen atoms with a graphite phase structure and unique optical and electronic properties.Compared with pure g-C_3N_4,composite g-C_3N_(4 )materials have great development prospect in the fields of biological imaging and biological detection attributed to their better detection performance and wider detection applications.In this paper,the applications of complex g-C_3N_4 in the detection of heavy metal ions,human macromolecules,cell imaging and other fluorescent probes were reviewed,and then the future development of composite g-C_3N_4 was prospected.
Graphite carbon nitride(g-C_3N_4)is a new type of optical material composed of carbon and nitrogen atoms with a graphite phase structure and unique optical and electronic properties.Compared with pure g-C_3N_4,composite g-C_3N_(4 )materials have great development prospect in the fields of biological imaging and biological detection attributed to their better detection performance and wider detection applications.In this paper,the applications of complex g-C_3N_4 in the detection of heavy metal ions,human macromolecules,cell imaging and other fluorescent probes were reviewed,and then the future development of composite g-C_3N_4 was prospected.
引文
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[32]Dong J,Zhao Y,Chen H Y,et al.Fabrication of PEGylated graphitic carbon nitride quantum dots as traceable,pH-sensitive drug delivery systems[J].NJCh,2018,42(17):14263-14270.
[2]Gu Y P,Cui R,Zhang Z L,et al.Ultrasmall near-infrared Ag2Se quantum dots with tunable fluorescence for in vivo imaging[J].J Am Chem Soc,2012,134(1):79-82.
[3]J P Z,Sangwook Kim,Shunsuke Ohnishi,et al.Size series of small indium arsenide-zinc aelenide core-shell nanocrystals and their application to in vivo imaging[J].J Am Chem Soc,2006,128(8):2526-2527.
[4]Masteri-Farahani M,Khademabbasi K,Mollatayefeh N.A selective morphine nanosensor derived from functionalized CdS quantum dots[J].Mate Lett,2018,228:68-71.
[5]刘珊珊,左桂福,王笑敏,等.固混法制备BiVO4/石墨相氮化碳复合物及其光催化性能表征[J].化工新型材料,2017,45(10):90-93.
[6]Zhang J,Chen Y,Wang X.Two-dimensional covalent carbon nitride nanosheets:synthesis,functionalization,and applications[J].Energy Environ Sci,2015,8(11):3092-3108.
[7]Liu J,Liu Y,Liu N,et al.Metal-free efficient photocatalyst for stable visible water splitting via a two-electron pathway[J].Sci,2015,46(23):970-974.
[8]Xiao D,Yuan D,He H,et al.Microwave-assisted one-step green synthesis of amino-functionalized fluorescent carbon nitride dots from chitosan[J].Luminescence,2013,28(4):612-615.
[9]Dong Y,Wang Q,Wu H,et al.Graphitic carbon nitride materials:sensing,imaging and therapy[J].Small,2016,12(39):5376-5393.
[10]Ji J,Wen J,Shen Y,et al.Simultaneous noncovalent modification and exfoliation of 2D carbon nitride for enhanced electrochemiluminescent biosensing[J].J Am Chem Soc,2017,139(34):11698-11701.
[11]Zhang X,Xie X,Wang H,et al.Enhanced photoresponsive ultrathin graphitic-phase C3N4 nanosheets for bioimaging[J].J Am Chem Soc,2013,135(1):18-21.
[12]余童,王海飞,王春林,等.复合光催化剂CNNS/CdS QDs的一步法合成及催化性能研究[J].化学研究与应用,2017,29(12):1878-1883.
[13]刘珊珊,左桂福,韩大庆,等.石墨氮化碳在荧光探针中的应用研究进展[J].现代化工,2017,37(11):202-205+207.
[14]Liu S,Dong W,Zeng X,et al.β-cyclodextrin modified g-C3N4 nanosheet:a fluorescent drug carrier with ultrahigh drug loading capacity and pH-responsive release[J].J Chem Technol Biotechnol,2018.
[15]Liu S,Guo Z,Zeng X,et al.Self assembly and controlled drug release of a nano-laminated graphite carbon nitride/methotrexate complex[J].J Mater Sci Mater Med,2018,29(8):116-112.
[16]Sun J,Malishev R,Azoulay A,et al.Carbon and nitrogen based nanosheets as fluorescent probes with tunable emission[J].Small,2018,14(21):1800516:1-6.
[17]Lin T,Zhong L,Wang J,et al.Graphite-like carbon nitrides as peroxidase mimetics and their applications to glucose detection[J].Biosensors Bioelectron,2014,59:89-93.
[18]Fina F,Irvine J T.The effect of Pt NPs crystallinity and distribution on the photocatalytic activity of Pt-g-C3N4[J].PCCP,2015,17(21):13929:1-6.
[19]Chen L,Song Z,Liu X,et al.Barbituric acid-modified graphitic carbon nitride nanosheets for ratiometric fluorescent detection of Cu2+[J].Analyst,2018,143(7):1609-1614.
[20]Wang H,Lu Q,Li M,et al.Electrochemically prepared oxygen and sulfur co-doped graphitic carbon nitride quantum dots for fluorescence determination of copper and silver ions and biothiols[J].Anal Chim Acta,2018,1027:121-129.
[21]李芳芳,聂锦丽,黄英,等.Ag掺杂的石墨型氮化碳材料光致发光性能的研究[J].化学研究与应用,2013,25(11):1470-1474.
[22]Jasman S M,Lintang H O,Yuliati L.Enhanced detection of nitrite ions over copper acetylacetonate/polymeric carbon nitride composites[J].Macromolecular Symposia,2017,371(1):84-93.
[23]Wang Y W,Wang L,An F,et al.Graphitic carbon nitride supported platinum nanocomposites for rapid and sensitive colorimetric detection of mercury ions[J].Anal Chim Acta,2017,980:72-78.
[24]Achadu O J,Revaprasadu N.Microwave-assisted synthesis of thymine-functionalized graphitic carbon nitride quantum dots as a fluorescent nanoprobe for mercury(II)[J].Mikrochim Acta,2018,185(10):461:1-8.
[25]Wang X,Li X,Chen W,et al.Phosphorus doped graphitic carbon nitride nanosheets as fluorescence probe for the detection of baicalein[J].Spectrochim Acta,Part A,2018,198:1-6.
[26]Yang H,Li X,Wang X,et al.Silver-doped graphite carbon nitride nanosheets as fluorescent probe for the detection of curcumin[J].Luminescence,2018:1-8.
[27]Jin X,Zhong Y,Chen L,et al.A palladium-doped graphitic carbon nitride nanosheet with high peroxidase-like activity:preparation,characterization,and application in glucose detection[J].Part Part Syst Char,2017:1700359:1-8.
[28]Ma T Y,Tang Y,Dai S,et al.Proton-functionalized two-dimensional graphitic carbon nitride nanosheet:an excellent metal-/label-free biosensing platform[J].Small,2014,10(12):2382-2389.
[29]Liao X,Li Z,Peng T,et al.Ultra-sensitive fluorescent sensor for intracellular miRNA based on enzyme-free signal amplification with carbon nitride nanosheet as a carrier[J].Luminescence the Journal of Biological&Chemical Luminescence,2017,32(8):1411-1416.
[30]Wu J,Yang S,Li J,et al.Electron injection of phosphorus doped g‐C3N4 quantum dots:controllable photoluminescence emission wavelength in the whole visible light range with high quantum yield[J].Adv Opt Mater,2016,4,2095-2101.
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[32]Dong J,Zhao Y,Chen H Y,et al.Fabrication of PEGylated graphitic carbon nitride quantum dots as traceable,pH-sensitive drug delivery systems[J].NJCh,2018,42(17):14263-14270.