常见儿童呼吸道病毒感染性疾病的临床特征
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摘要
儿童急性呼吸道感染是临床的常见病,是导致儿童死亡的一个重要原因,病毒感染在其中占有重要地位。绝大多数病毒感染无特异性临床特征,但也有部分病毒感染临床表现特征性较强。熟悉不同病毒感染的临床特征对于临床早期及时的明确病原以及合理用药有着深远的意义。
Acute respiratory infection in children is a common clinical disease and is an important cause of death in children. Viral infection plays an important role in acute respiratory infection. Most virus infections have no specific clinical characteristics,but some have. To be familiar with the clinical features of different virus infection is significant for early clinical diagnosis,prompt identification of pathogens and rational drug use.
Acute respiratory infection in children is a common clinical disease and is an important cause of death in children. Viral infection plays an important role in acute respiratory infection. Most virus infections have no specific clinical characteristics,but some have. To be familiar with the clinical features of different virus infection is significant for early clinical diagnosis,prompt identification of pathogens and rational drug use.
引文
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[24]宋明辉,赵林清,钱渊,等.不同基因型人鼻病毒感染所致儿童急性呼吸道感染的研究[J].中华儿科杂志,2013,51(12):903-908.
[25]Qaisy LM,Meqdam MM,Alkhateeb A,et al.Human metapneu?movirus in Jordan:prevalence and clinical symptoms in hospi?talized pediatric patients and molecular virus characteriza?tion[J].Diagn Microbiol Infect Dis,2012,74(3):288-291.
[26]谭嘉红,季伟,张新星,等.2009-2016年苏州地区儿童呼吸道感染博卡病毒流行病学特征分析[J].中国实用儿科杂志,2018,33(6):442-445.
[27]Lau SK,Yip CC,Quc TL,et al.Clinical and molecular epide?miology of human bocavirus in respiratory and fecal samples from children in Hong Kong[J].J Infect Dis,2007,196(7):986-993.
[28]Volz S,Schildgen O,Klinkenberg D,et al.Prospective study of Human bocavirus(Hbo V)infection in a pediatric university hospital in Germany 2005/2006[J].H Clin Virol,2007,40(3):229-235.
[2]Black RE,Cousens S,Johnson HL,et al.Global,regional,and national causes of child mortality in 2008:a systematic analy?sis[J].Lancet,2010,375(9730):1969-1987.
[3]Mahony JB.Nucleic acid amplification-based diagnosis of respi?ratory virus infections[J].Expert Rev Anti Infect Ther,2010,8(11):1273-1292.
[4]Turner P,Turner C,Watthanaworawit W,et al.Respiratory virus surveillance in hospitalised pneumonia patients on the Thai?land-Myanmar border[J].BMC Infect Dis,2013,13:434.
[5]Cai XY,Wang Q,Lin GY,et al.Respiratory virus infections among children in South China[J].J Med Virol,2014,86(7):1249-55.
[6]顾文婧,季伟,张新星,等.2011-2014年苏州儿童医院3596例喘息儿童的病原学分析[J].中国实用儿科杂志,2016,31(3):196-201.
[7]Piedimonte G,Perez MK.Respiratory syncytial virus infection and bronchiolitis[J].Pediatr Rev,2014,35(12):519-530.
[8]Simpson MD,Kieke BA Jr,Sundaram ME,et al.Incidence of medically attended respiratory syncytial virus and influenza ill?nesses in children 6-59 months old during four seasons[J].Open Forum Infect Dis,2016,3(2):ofw081.
[9]Zhang Q,Guo Z,Bai Z,et al.A 4-year prospective study to de?termine risk factors for severe community-acquired pneumonia in southern China[J].Pediatr Pulmonol,2013,48(4):390-397.
[10]胡亚美,江载芳,申昆玲,等.诸福棠实用儿科学[M].8版.北京:人民卫生出版社,2015:1274.
[11]刘秀云,江载芳.腺病毒肺炎后遗症的再认识[J].临床儿科杂志,2009,27(1):91-93.
[12]卫生部流行性感冒诊断与治疗指南编撰专家组.流行性感冒诊断与治疗指南(2011版)[J].中华结核和呼吸杂志,2011,34(10):725-734.
[13]颜玉炳,蒋丽娜,刘红莲,等.流感样病例中流感病毒阳性检出率的相关因素分析[J].中华疾病控制杂志,2015,19(3):310-312.
[14]Wang D,Zhang T,Wu J,et al.Socio-economic burden of influenza among children younger than 5 years in the outpatient setting in Suzhou,China[J].PLo S One,2013,8(8):e69035.
[15]Jev?nik M1,Ur?i?T,Zigon N,et al.Coronavirus infections in hospitalized pediatric patients with acute respiratory tract dis?ease[J].BMC Infect Dis,2012,12:365.
[16]Huang G,Yu D,Mao N,et al.Viral etiology of acute respiratory infection in Gansu Province,China,2011[J].PLo S One,2013,8(5):e64254.
[17]Branche AR,Falsey AR.Parainfluenza virus infection[J].Semin Respir Crit Care Med,2016,37(4):538-554.
[18]Schomacker H,Schaap-Nutt A,Collins PL,et al.Pathogenesis of acute respiratory illness caused by human parainfluenza vi?ruses[J].Curr Opin Virol,2012,2(3):294-299.
[19]Williams DJ,Shah SS.Community-acquired pneumonia in the Conjugate Vaccine Era[J].J Pediatric Infect Dis Soc,2012,1(4):314-328.
[20]Lau SK,Yip CC,Lin AW,et al.Clinical and molecular epide?miology of human rhinovirus C in children and adult in Hong Kong reveal a possible distinct human rhinovirus C sub?group[J].J Infect Dis,2009,200(1):1096-1103.
[21]Sigurs N,Bjarnason R,Sigurbergsson F,et al.Respiratory syn?cytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7[J].Am J Respir Crit Care Med,2000,161(5):1501-1507.
[22]Cox DW,Le Sou?f PN.Rhinovirus and the developing lung[J].Paediatr Respir Rev,2014,15(3):268-274.
[23]艾军红,谢正德,刘春艳,等.婴幼儿呼吸道合胞病毒和人鼻病毒急性下呼吸道感染临床特征及随访研究[J].中华临床医师杂志(电子版),2013,(21):20-22.
[24]宋明辉,赵林清,钱渊,等.不同基因型人鼻病毒感染所致儿童急性呼吸道感染的研究[J].中华儿科杂志,2013,51(12):903-908.
[25]Qaisy LM,Meqdam MM,Alkhateeb A,et al.Human metapneu?movirus in Jordan:prevalence and clinical symptoms in hospi?talized pediatric patients and molecular virus characteriza?tion[J].Diagn Microbiol Infect Dis,2012,74(3):288-291.
[26]谭嘉红,季伟,张新星,等.2009-2016年苏州地区儿童呼吸道感染博卡病毒流行病学特征分析[J].中国实用儿科杂志,2018,33(6):442-445.
[27]Lau SK,Yip CC,Quc TL,et al.Clinical and molecular epide?miology of human bocavirus in respiratory and fecal samples from children in Hong Kong[J].J Infect Dis,2007,196(7):986-993.
[28]Volz S,Schildgen O,Klinkenberg D,et al.Prospective study of Human bocavirus(Hbo V)infection in a pediatric university hospital in Germany 2005/2006[J].H Clin Virol,2007,40(3):229-235.