猴耳环消炎颗粒治疗婴幼儿过敏性结肠炎40例
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摘要
目的:探讨猴耳环消炎颗粒辅助治疗婴幼儿过敏性结肠炎的临床效果。方法:将80例患儿随机分为观察组和对照组,每组40例。对照组给予对症支持处理,观察组在此基础上使用猴耳环消炎颗粒,3～6 g/次,3次/d。连续治疗7天为1疗程,共治疗2个疗程。比较2组治疗后进食流质、半流质以及普通饮食时间,大便成形时间及规律大便时间,住院时间,1月后随访生活质量评分。结果:治疗后进食流质、半流质以及普通饮食时间观察组均显著早于对照组(P<0.05),大便成形时间、规律大便时间观察组显著早于对照组(P<0.05),干预后生活质量观察组优于对照组(P<0.05),住院时间观察组显著短于对照组(P<0.05)。结论:针对小儿过敏性结肠炎使用猴耳环消炎颗粒,能更好的缓解患儿临床症状,促进肠道内环境修复,改善大便形态,提高生活质量,缩短住院时间。
Objective: To discuss curative effects of HouErHuan XiaoYan granules as adjunctive therapy(AT)in treating infantile allergic colitis(AC). Methods: Eighty children were divided into the observation group and the control group randomly, 40 cases each group. The control group accepted symptomatic supporting therapy, and the observation group took HouErHuan XiaoYan granules based on the former therapy, 3 ～6 g each time, three times each day. Seven days were one course, both groups were treated for two courses. The scores of quality life in one-month follow-ups, hospitalization time, the time of regular bowel movement, the time of stool formation, the time of eating liquid diet, semi-liquid diet and common food were compared between both groups after treating. Results: The observation group was earlier than the control group in the time of eating liquid diet, semi-liquid diet and common food after treating remarkably(P<0.05), the time of stool formation and the time of regular bowel movement(P<0.05), after the intervention, the observation group was superior to the control group in life quality after the intervention(P<0.05), the observation group was shorter than the control group in hospitalization time notably(P<0.05). Conclusion: HouErHuan XiaoYan granules as AT in treating infantile AC could relieve clinical symptoms of the children, promote intestinal environment recovery, improve the shape of the stool, raise life quality and shorten hospitalization time.
Objective: To discuss curative effects of HouErHuan XiaoYan granules as adjunctive therapy(AT)in treating infantile allergic colitis(AC). Methods: Eighty children were divided into the observation group and the control group randomly, 40 cases each group. The control group accepted symptomatic supporting therapy, and the observation group took HouErHuan XiaoYan granules based on the former therapy, 3 ～6 g each time, three times each day. Seven days were one course, both groups were treated for two courses. The scores of quality life in one-month follow-ups, hospitalization time, the time of regular bowel movement, the time of stool formation, the time of eating liquid diet, semi-liquid diet and common food were compared between both groups after treating. Results: The observation group was earlier than the control group in the time of eating liquid diet, semi-liquid diet and common food after treating remarkably(P<0.05), the time of stool formation and the time of regular bowel movement(P<0.05), after the intervention, the observation group was superior to the control group in life quality after the intervention(P<0.05), the observation group was shorter than the control group in hospitalization time notably(P<0.05). Conclusion: HouErHuan XiaoYan granules as AT in treating infantile AC could relieve clinical symptoms of the children, promote intestinal environment recovery, improve the shape of the stool, raise life quality and shorten hospitalization time.
引文
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[14]刘向东.双歧杆菌四联活菌片加猴耳环消炎颗粒治疗慢性肠炎临床观察[J].中国现代药物应用,2013,5(13):62-63.
[15]彭亮,李诒光,陈杰,等.我国猴耳环属植物药理作用及临床应用研究进展[J].江西中医药大学学报,2015,27(6):116-120.
[16]丁鸿飞.猴耳环消炎颗粒联合利巴韦林喷剂治疗小儿疱疹性咽峡炎的疗效观察[J].浙江中医药大学学报,2013,35(6):850-852.
[2]许桂天.儿童过敏性结肠炎的临床诊治分析[J].大家健康,2013,7(10):195-196.
[3]赵红梅,游洁玉,徐斌,等.96例婴儿过敏性直肠结肠炎临床特征分析[J].中国当代儿科杂志,2014,16(9):914-918.
[4]戎赞华.儿童消化道过敏判断及应对策略[J].中国实用儿科杂志,2015,30(1):42-46.
[5]李志强,王静仪.猴耳环消炎胶囊中没食子酸、槲皮苷的含量测定[J].广东药学院学报,2013,29(4):400-404.
[6]胡兰.猴耳环消炎颗粒治疗儿童急性化脓性扁桃体炎疗效观察[J].四川中医,2013,31(12):106-108.
[7]彭亮,李诒光,陈杰,等.猴耳环消炎颗粒质量标准[J].中国实验方剂学杂志,2015,21(14):59-61.
[8]杜旭红.猴耳环消炎颗粒治疗小儿急性扁桃体炎50例临床疗效观察[J].实用中西医结合临床,2012,12(3):72-73.
[9]刘小莉,刘琳,文花,等.猴耳环消炎颗粒治疗小儿细菌性肠炎60例[J].实用中西医结合临床,2016,16(8):29-31.
[10]王家蔚,郁峰.猴耳环消炎颗粒治疗急性上呼吸道感染疗效观察[J].实用中西医结合临床,2013,13(3):64-65.
[11]陈新伟,陈进,余晓芬,等.利巴韦林气雾剂及颗粒治疗婴幼儿手足口病的比较研究[J].北方药学,2015,12(12):75-76.
[12]陶红,张韬,林庆锋,等.口服中成药防治手足口病的应用进展[J].现代中西医结合杂志,2012,21(17):1930-1931.
[13]刘丽春,张美英,郭甜,等.炎琥宁注射液配合清热消蛾颗粒治疗儿童急性扁桃体炎的疗效观察[J].内蒙古医科大学学报,2015,37(s2):65-67.
[14]刘向东.双歧杆菌四联活菌片加猴耳环消炎颗粒治疗慢性肠炎临床观察[J].中国现代药物应用,2013,5(13):62-63.
[15]彭亮,李诒光,陈杰,等.我国猴耳环属植物药理作用及临床应用研究进展[J].江西中医药大学学报,2015,27(6):116-120.
[16]丁鸿飞.猴耳环消炎颗粒联合利巴韦林喷剂治疗小儿疱疹性咽峡炎的疗效观察[J].浙江中医药大学学报,2013,35(6):850-852.