儿童耐β内酰胺类肺炎链球菌耐药相关基因研究进展
摘要
<正>近年来,我国肺炎链球菌感染发病率逐渐升高,同时,欧美等其他国家也出现了较为明显的肺炎链球菌感染性疾病发病率增长的现象。β内酰胺类抗生素是临床治疗肺炎链球菌感染的常用药,而肺炎链球菌耐β内酰胺类抗菌药物现象的出现则严重影响了这类药物的应用及治疗效果。因此,本研究将与儿童耐β内酰胺类肺炎链球菌耐药相关基因有关的研究综述如下。
引文
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2 张范华,林军立,鲍惠妙,等.肺炎链球菌pbp2B基因突变与β-内酰胺类抗生素耐药相关性的研究[J].中国卫生检验杂志,2015,20(6):1423-1425,1435
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7孙爱华,樊欢,夏肖萍,等.肺炎链球菌ciaH/R基因重组表达及CiaH/R与β-内酰胺类耐药相关性[J].浙江大学学报(医学版),2015,37(6):605-611
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9 朱奇峰.用于自动反向对接的β-内酰胺类药物靶点蛋白结构数据库的构建[D].西南大学,2015
10 Uno.Changes in antimicrobial susceptibilities of Streptococcus pneumoniae detected in the nasopharynx of children with upper airway infection[J].Pediatric Otorhinolaryngology Japan,2009,30(3):232-247
11 Bedenic B,Sardelic S,Ladavac M.MULTIRESISTANT BACTERIA.[J].Acta medica Croatica:casopis Hravatske akademije medicinskih znanosti,2015,69(3):211-216
12 柏晓辉.肺炎链球菌肽聚糖水解酶LytB与耐药相关蛋白Sp0010的结构与功能研究[D].中国科学技术大学,2015
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14 张春玲,许亚亚,牛津,等.耐β-内酰胺类抗生素肺炎链球菌青霉素结合蛋白PBPs的氨基酸基因变异[J].中国微生态学杂志,2016,24(12):1088-1092
15 Matsumoto Ayumi,Takeyama Aya,Hashimoto Koichi,et al.Nonantibiotic treatment for pediatric outpatients with common cold inhibits the emergence of drug resistant pneumococci[J].Fukushima Journal of Medical Science,2015,56(1):28-37
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18 樊欢,孙爱华,夏肖萍,等.肺炎链球菌comD/E/C基因重组表达及ComD/C与β-内酰胺类抗生素耐药的相关性[J].浙江大学学报(医学版),2009,38(3):276-282
19 Michael JStanhope,Tristan Lefébure,Stacey LWalsh,et al.Heather Amrine-Madsen.Positive selection in penicillin-binding proteins 1a,2b,and 2x from Streptococcus pneumoniae and its correlation with amoxicillin resistance development[J].Infection,Genetics and Evolution,2015,8(3):331-339
20 石燕华,李昌崇.肺炎链球菌对β-内酰胺类及大环内酯类抗生素耐药基因的研究进展[J].国际呼吸杂志,2009,29(17):1062-1064
21 张春玲,许亚亚,牛津,等.耐β-内酰胺类抗生素肺炎链球菌青霉素结合蛋白PBPs的氨基酸基因变异[J].中国微生态学杂志,2012,24(12):1088-1092
22 Müller Miriam,Marx Patrick,Hakenbeck Regine,et al.Effect of new alleles of the histidine kinase gene ciaH on the activity of the response regulator CiaR in Streptococcus pneumoniae R6[J].Microbiology,2011,157(11):3104-3112
23 丁晶晶,苗立云,李燕,等.江苏省南京地区肺炎链球菌对β-内酰胺类抗生素耐药及传播机制[J].实用临床医药杂志,2015,18(9):22-26
24 Ma X,Yao KH,Yu SJ,et al.Genotype replacement within serotype 23F Streptococcus pneumoniae in Beijing,China:characterization of serotype 23F[J].Epidemiology and Infection,2013,141(8):1690-1696
25 樊欢.二元信号系统ComD/ComE与肺炎链球菌对β-内酰胺类抗生素耐药的相关性[D].浙江大学,2011
26 黄璐.肺炎链球菌在苏州地区儿童急性呼吸道感染中的地位及其耐β-内酰胺类抗菌药物相关基因的研究[D].苏州大学,2009
27 杨晓华,陈燕辉,石冬梅,等.儿童呼吸道标本肺炎链球菌的耐药性监测[J].中国感染与化疗杂志,2018,18(3):292-296
2 张范华,林军立,鲍惠妙,等.肺炎链球菌pbp2B基因突变与β-内酰胺类抗生素耐药相关性的研究[J].中国卫生检验杂志,2015,20(6):1423-1425,1435
3 Vanesa Reijtman,Paula Gagetti,Diego Faccone,et al.Macrolide resistance in Streptococcus pneumoniae isolated from Argentinian pediatric patients suffering from acute otitis media[J].Revista Argentina de Microbiologia,2015,45(4):262-266
4 RR Reinert.The antimicrobial resistance profile of Streptococcus pneumoniae[J].Clinical Microbiology and Infection,2015,15(3):7-11
5 胡付品,郭燕,朱德妹,等.2017年CHINET中国细菌耐药性监测[J].中国感染与化疗杂志,2018,18(3):241-251
6 周会霞,杨广龙,李银华,等.儿科β-内酰胺类抗生素耐药肺炎链球菌分子分型及传播机制的研究[J].现代医学,2017,45(2):215-220
7孙爱华,樊欢,夏肖萍,等.肺炎链球菌ciaH/R基因重组表达及CiaH/R与β-内酰胺类耐药相关性[J].浙江大学学报(医学版),2015,37(6):605-611
8 Huang Yong,Wan Genping,Zhou Zhenwen,et al.Antimicrobial resistance and penicillin resistance-associated genes of Streptococcus pneumoniae isolated from children with respiratory tract infection[J].Chinese Contemporary Pediatric Journal,2015,11(8):623-626
9 朱奇峰.用于自动反向对接的β-内酰胺类药物靶点蛋白结构数据库的构建[D].西南大学,2015
10 Uno.Changes in antimicrobial susceptibilities of Streptococcus pneumoniae detected in the nasopharynx of children with upper airway infection[J].Pediatric Otorhinolaryngology Japan,2009,30(3):232-247
11 Bedenic B,Sardelic S,Ladavac M.MULTIRESISTANT BACTERIA.[J].Acta medica Croatica:casopis Hravatske akademije medicinskih znanosti,2015,69(3):211-216
12 柏晓辉.肺炎链球菌肽聚糖水解酶LytB与耐药相关蛋白Sp0010的结构与功能研究[D].中国科学技术大学,2015
13 韩娇,韩志英.儿童肺炎链球菌耐药性及耐药基因分型研究[J].临床医药文献电子杂志,2018,5(35):195-196
14 张春玲,许亚亚,牛津,等.耐β-内酰胺类抗生素肺炎链球菌青霉素结合蛋白PBPs的氨基酸基因变异[J].中国微生态学杂志,2016,24(12):1088-1092
15 Matsumoto Ayumi,Takeyama Aya,Hashimoto Koichi,et al.Nonantibiotic treatment for pediatric outpatients with common cold inhibits the emergence of drug resistant pneumococci[J].Fukushima Journal of Medical Science,2015,56(1):28-37
16 俞春松,吴学虹,黄琴美,等.肺炎链球菌pbp2B、pbp2X和pbp1A基因突变与β-内酰胺类耐药相关性研究[J].中国卫生检验杂志,2016,20(12):3249-3252
17 季伟,黄璐,吴军华,等.肺炎链球菌对β-内酰胺类抗生素耐药相关基因的研究[J].江浙沪儿科学术会议暨儿科学基础与临床研究进展学术班,2009
18 樊欢,孙爱华,夏肖萍,等.肺炎链球菌comD/E/C基因重组表达及ComD/C与β-内酰胺类抗生素耐药的相关性[J].浙江大学学报(医学版),2009,38(3):276-282
19 Michael JStanhope,Tristan Lefébure,Stacey LWalsh,et al.Heather Amrine-Madsen.Positive selection in penicillin-binding proteins 1a,2b,and 2x from Streptococcus pneumoniae and its correlation with amoxicillin resistance development[J].Infection,Genetics and Evolution,2015,8(3):331-339
20 石燕华,李昌崇.肺炎链球菌对β-内酰胺类及大环内酯类抗生素耐药基因的研究进展[J].国际呼吸杂志,2009,29(17):1062-1064
21 张春玲,许亚亚,牛津,等.耐β-内酰胺类抗生素肺炎链球菌青霉素结合蛋白PBPs的氨基酸基因变异[J].中国微生态学杂志,2012,24(12):1088-1092
22 Müller Miriam,Marx Patrick,Hakenbeck Regine,et al.Effect of new alleles of the histidine kinase gene ciaH on the activity of the response regulator CiaR in Streptococcus pneumoniae R6[J].Microbiology,2011,157(11):3104-3112
23 丁晶晶,苗立云,李燕,等.江苏省南京地区肺炎链球菌对β-内酰胺类抗生素耐药及传播机制[J].实用临床医药杂志,2015,18(9):22-26
24 Ma X,Yao KH,Yu SJ,et al.Genotype replacement within serotype 23F Streptococcus pneumoniae in Beijing,China:characterization of serotype 23F[J].Epidemiology and Infection,2013,141(8):1690-1696
25 樊欢.二元信号系统ComD/ComE与肺炎链球菌对β-内酰胺类抗生素耐药的相关性[D].浙江大学,2011
26 黄璐.肺炎链球菌在苏州地区儿童急性呼吸道感染中的地位及其耐β-内酰胺类抗菌药物相关基因的研究[D].苏州大学,2009
27 杨晓华,陈燕辉,石冬梅,等.儿童呼吸道标本肺炎链球菌的耐药性监测[J].中国感染与化疗杂志,2018,18(3):292-296