注射用血栓通(冻干)在脑血管疾病的临床运用进展
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摘要
目的:研究注射用血栓通(冻干)近几年在脑血管疾病的临床运用进展。方法:通过查询近几年中国知网数据库中的相关文献,总结注射用血栓通(冻干)在脑血管疾病方面的临床运用。结果:注射用血栓通(冻干)在脑血管疾病方面主要用于治疗急性缺血性脑卒中、脑梗死后遗症、短暂性脑缺血发作、后循环缺血性眩晕、脑血栓形成等,并取得良好的临床疗效。注射用血栓通(冻干)有利于恢复脑血管疾病的神经功能,改善患者的血液流变学,提高脑部组织的血液流量,可有效改善临床症状。结论:注射用血栓通(冻干)在脑血管疾病临床运用广泛,疗效显著。
Objective: To study the clinical application progress of Xueshuantong for injection(Lyophilized) in cerebrovascular diseases in recent years. Methods: The clinical application of Xueshuantong for injection(Lyophilized) in cerebrovascular diseases was summarized by consulting the relevant literatures in CNKI database in recent years. Result: Xueshuantong for injection(Lyophilized) is mainly used in the treatment of acute ischemic stroke, sequelae of cerebral infarction, transient ischemic attack, posterior circulation ischemic vertigo, cerebral thrombosis and so on, and has achieved good clinical efficacy. Xueshuantong for injection(freeze-drying) is beneficial to restore the nervous function of cerebrovascular diseases, improve the hemorheology of patients, increase the blood flow of brain tissue, and effectively improve the clinical symptoms. Conclusion: Xueshuantong for injection(Lyophilized) is widely used in clinical treatment of cerebrovascular diseases and has a remarkable effect.
Objective: To study the clinical application progress of Xueshuantong for injection(Lyophilized) in cerebrovascular diseases in recent years. Methods: The clinical application of Xueshuantong for injection(Lyophilized) in cerebrovascular diseases was summarized by consulting the relevant literatures in CNKI database in recent years. Result: Xueshuantong for injection(Lyophilized) is mainly used in the treatment of acute ischemic stroke, sequelae of cerebral infarction, transient ischemic attack, posterior circulation ischemic vertigo, cerebral thrombosis and so on, and has achieved good clinical efficacy. Xueshuantong for injection(freeze-drying) is beneficial to restore the nervous function of cerebrovascular diseases, improve the hemorheology of patients, increase the blood flow of brain tissue, and effectively improve the clinical symptoms. Conclusion: Xueshuantong for injection(Lyophilized) is widely used in clinical treatment of cerebrovascular diseases and has a remarkable effect.
引文
[1]王旭梅,赵莼,王少侠,等.注射用血栓通(冻干)透过血脑屏障研究[J].药物评价研究,2015,38(4):384-389.
[2]李琦,吕静,杨妹琴,等.丁苯酞联合血栓通治疗缺血性脑卒中患者神经功能的效果[J].中国生化药物杂志,2014,34(6):107-109.
[3]周劲建,郭忠伟.阿托伐他汀钙联合血栓通注射液治疗脑梗死的临床疗效研究[J].中国临床药理学杂志,2015,31(24)2375-2377.
[4]卫晓红,刘冀荣,崔惠敏.奥扎格雷钠联合血栓通治疗急性脑梗死的效果观察[J].中国实用神经疾病杂志,2016,19(17)122-123.
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[6]张欣.丁苯酞联合血栓通对脑梗死患者血清炎性因子及预后影响的临床研究[J].河北医药,2014,36(16):2412-2415.
[7]方芳,谈山峰,陈巧雅,等.法舒地尔联合血栓通治疗老年2型糖尿病合并脑梗死患者临床观察[J].济宁医学院学报,2015,38(3):171-172.
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[9]王英双,袁建喜.注射用血栓通联合生脉注射液治疗缺血性脑卒中临床研究[J].中外医学研究,2018,16(14):28-30.
[10]高俊禄,武海霞,史圣华.针灸按摩加中药内服治疗中风后遗症150例临床观察[J].内蒙古中医药,2014,33(1):67.
[11]郭培德.ADL量表评价血栓通对脑梗死后遗症患者康复效果的影响[J].中国继续医学教育,2016,8(33):230-231.
[12]王涛.血栓通联合吡拉西坦治疗老年性脑梗死后遗症的临床效果评价[J].中国实用医药,2017,12(3):95-97.
[13]韩仲岩,赵仁亮.对短暂性脑缺血发作及其和脑梗死关系的重新认识[J].临床神经病学杂志,2004,17(6):401.
[14]黄宇.不同剂量血栓通对短暂性脑缺血发作的疗效[J].中国实用神经疾病杂志,2014,17(11):98-99.
[15]方国庆.参麦注射液联用血栓通治疗短暂性脑缺血发作临床观察[J].中医药临床杂志,2014,26(5):479-480.
[16]梁利颜,廖建军.血栓通联合低分子肝素钙在治疗短暂性脑缺血发作中的效果观察[J].中国当代医药,2016,23(28):53-55.
[17]何俐.眩晕与后循环缺血[J].中华保健医学杂志,2014,16(3):171-173.
[18]闫浩林.天麻素注射液联合血栓通治疗后循环缺血性眩晕的临床疗效[J].中国实用神经疾病杂志,2016,19(9):118-119.
[19]郭润芳,李志伟.血栓通联合氟桂利嗪治疗椎-基底动脉供血不足性眩晕[J].西南国防医药,2017,27(11):1206-1208.
[20]张丛林.血栓通联合丹参川芎嗪治疗椎-基底动脉供血不足性眩晕的疗效及对血液流变学的影响[J].河北医药,2017,39(1):127-129,132.
[21]刘可威.血栓通提高长春西汀治疗后循环缺血综合征的临床效果[J].华夏医学,2018,31(1);69-71.
[22]张晓慧.血栓通注射液治疗脑血栓形成43例的临床疗效观察[J].中国实用医药,2015,10(3):9-10.
[23]黄春.血栓通注射液治疗脑血栓形成40例疗效观察[J].世界最新医学信息文摘,2016,16(75):384-385.
[24]王葆华.血栓通注射液辅助治疗脑血栓形成临床疗效观察分析[J].大家健康,2014,8(22):151.
[25]闫小燕.血栓通注射液治疗脑血栓形成患者中的临床疗效及护理[J].海峡药学,2018,30(4):191-192.
[26]Krishnamurthi RV,Feigin V L,Forouzanfar M H,et al.Global and re-gional burden of first-ever ischaemic and haemorrhagic stroke during1990-2010:findings from the Global Burden of Disease Study 2010[J].The Lancet Global Health,2013,1(5):e259-e281.
[27]杜瑶,李欣,冉利,等.星形胶质细胞在缺血性脑血管疾病中的双重作用[J].中风与神经疾病杂志,2018,35(9):841-844.
[2]李琦,吕静,杨妹琴,等.丁苯酞联合血栓通治疗缺血性脑卒中患者神经功能的效果[J].中国生化药物杂志,2014,34(6):107-109.
[3]周劲建,郭忠伟.阿托伐他汀钙联合血栓通注射液治疗脑梗死的临床疗效研究[J].中国临床药理学杂志,2015,31(24)2375-2377.
[4]卫晓红,刘冀荣,崔惠敏.奥扎格雷钠联合血栓通治疗急性脑梗死的效果观察[J].中国实用神经疾病杂志,2016,19(17)122-123.
[5]李杰.川芎嗪联合血栓通治疗缺血性脑卒中的疗效分析[J].中国实用神经疾病杂志,2014,17(17):108-109.
[6]张欣.丁苯酞联合血栓通对脑梗死患者血清炎性因子及预后影响的临床研究[J].河北医药,2014,36(16):2412-2415.
[7]方芳,谈山峰,陈巧雅,等.法舒地尔联合血栓通治疗老年2型糖尿病合并脑梗死患者临床观察[J].济宁医学院学报,2015,38(3):171-172.
[8]何龙祯.急性脑梗死采用血栓通和降纤酶治疗的疗效观察[J].中西医结合心血管病杂志,2015,3(15):131-132.
[9]王英双,袁建喜.注射用血栓通联合生脉注射液治疗缺血性脑卒中临床研究[J].中外医学研究,2018,16(14):28-30.
[10]高俊禄,武海霞,史圣华.针灸按摩加中药内服治疗中风后遗症150例临床观察[J].内蒙古中医药,2014,33(1):67.
[11]郭培德.ADL量表评价血栓通对脑梗死后遗症患者康复效果的影响[J].中国继续医学教育,2016,8(33):230-231.
[12]王涛.血栓通联合吡拉西坦治疗老年性脑梗死后遗症的临床效果评价[J].中国实用医药,2017,12(3):95-97.
[13]韩仲岩,赵仁亮.对短暂性脑缺血发作及其和脑梗死关系的重新认识[J].临床神经病学杂志,2004,17(6):401.
[14]黄宇.不同剂量血栓通对短暂性脑缺血发作的疗效[J].中国实用神经疾病杂志,2014,17(11):98-99.
[15]方国庆.参麦注射液联用血栓通治疗短暂性脑缺血发作临床观察[J].中医药临床杂志,2014,26(5):479-480.
[16]梁利颜,廖建军.血栓通联合低分子肝素钙在治疗短暂性脑缺血发作中的效果观察[J].中国当代医药,2016,23(28):53-55.
[17]何俐.眩晕与后循环缺血[J].中华保健医学杂志,2014,16(3):171-173.
[18]闫浩林.天麻素注射液联合血栓通治疗后循环缺血性眩晕的临床疗效[J].中国实用神经疾病杂志,2016,19(9):118-119.
[19]郭润芳,李志伟.血栓通联合氟桂利嗪治疗椎-基底动脉供血不足性眩晕[J].西南国防医药,2017,27(11):1206-1208.
[20]张丛林.血栓通联合丹参川芎嗪治疗椎-基底动脉供血不足性眩晕的疗效及对血液流变学的影响[J].河北医药,2017,39(1):127-129,132.
[21]刘可威.血栓通提高长春西汀治疗后循环缺血综合征的临床效果[J].华夏医学,2018,31(1);69-71.
[22]张晓慧.血栓通注射液治疗脑血栓形成43例的临床疗效观察[J].中国实用医药,2015,10(3):9-10.
[23]黄春.血栓通注射液治疗脑血栓形成40例疗效观察[J].世界最新医学信息文摘,2016,16(75):384-385.
[24]王葆华.血栓通注射液辅助治疗脑血栓形成临床疗效观察分析[J].大家健康,2014,8(22):151.
[25]闫小燕.血栓通注射液治疗脑血栓形成患者中的临床疗效及护理[J].海峡药学,2018,30(4):191-192.
[26]Krishnamurthi RV,Feigin V L,Forouzanfar M H,et al.Global and re-gional burden of first-ever ischaemic and haemorrhagic stroke during1990-2010:findings from the Global Burden of Disease Study 2010[J].The Lancet Global Health,2013,1(5):e259-e281.
[27]杜瑶,李欣,冉利,等.星形胶质细胞在缺血性脑血管疾病中的双重作用[J].中风与神经疾病杂志,2018,35(9):841-844.