通窍活血汤联合窄谱中波紫外线治疗口腔扁平苔癣的临床疗效分析
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摘要
目的:分析通窍活血汤联合窄谱中波紫外线治疗口腔扁平苔癣的临床疗效。方法:将60例口腔扁平苔藓患者作为研究对象,将其按照就诊时间分为参照组(就诊时间2016年1月—2016年12月)与治疗组(就诊时间2017年1月—2017年12月),参照组给予窄谱中波紫外线治疗,治疗组在参照组基础上配合通窍活血汤。比较两组患者治疗效果。结果:参照组总有效率(66.67%)显著低于治疗组总有效率(93.33%)(P<0.05);治疗前两组患者血浆黏度与红细胞压积无明显差异(P>0.05);治疗后,治疗组血浆黏度改善明显优于参照组(P<0.05);但两组患者红细胞压积无明显差异(P>0.05)。结论:为口腔扁平苔藓患者进行通窍活血汤联合窄谱中波紫外线治疗效果显著,可以有效提高治疗效果,治疗后血浆黏度得到明显改善,值得临床大力推广使用。
Objective:To analyze the clinical effect of Tongqiao Huoxue Decoction combined with narrow band ultraviolet B on oral lichen planus. Methods:Sixty patients with oral lichen planus were studied. They were divided into control group(January 2016 to December 2016) and treatment group(January 2017 to December 2017) according to the time of treatment. Treatment group added Tongqiao Huoxue Decoction. We compared the therapeutic effect between the two groups. Results:The total effective rate of the reference group was significantly lower than that of the treatment group(66.67%), which was significantly lower than that of the treatment group(93.3%)(P<0.05). There was no significant difference in plasma viscosity and hematocrit(P>0.05) between the two groups before treatment.After treatment, the improvement of plasma viscosity in the treatment group was better than that of the reference group(P<0.05).Conclusion: The combined narrow-spectrum medium-wave ultraviolet(UV) treatment of Tongqiao Huoxue Decoctioncombined with narrow-spectrum medium-wave ultraviolet(UV) treatment in the patients with oral lichen is remarkable, which can effectively improve the therapeutic effect and improve the plasma viscosity after treatment, worthy of clinical intensive popularization and use.
Objective:To analyze the clinical effect of Tongqiao Huoxue Decoction combined with narrow band ultraviolet B on oral lichen planus. Methods:Sixty patients with oral lichen planus were studied. They were divided into control group(January 2016 to December 2016) and treatment group(January 2017 to December 2017) according to the time of treatment. Treatment group added Tongqiao Huoxue Decoction. We compared the therapeutic effect between the two groups. Results:The total effective rate of the reference group was significantly lower than that of the treatment group(66.67%), which was significantly lower than that of the treatment group(93.3%)(P<0.05). There was no significant difference in plasma viscosity and hematocrit(P>0.05) between the two groups before treatment.After treatment, the improvement of plasma viscosity in the treatment group was better than that of the reference group(P<0.05).Conclusion: The combined narrow-spectrum medium-wave ultraviolet(UV) treatment of Tongqiao Huoxue Decoctioncombined with narrow-spectrum medium-wave ultraviolet(UV) treatment in the patients with oral lichen is remarkable, which can effectively improve the therapeutic effect and improve the plasma viscosity after treatment, worthy of clinical intensive popularization and use.
引文
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[15] 刘运龙. 银杏达莫注射液、依达拉奉联合半夏白术天麻汤、通窍活血汤治疗急性脑梗塞128例临床分析[J]. 北方药学, 2017, 14(8):37.
[16] 朱海平. 银杏达莫注射液、依达拉奉联合半夏白术天麻汤通窍活血汤治疗急性脑梗塞128例临床分析[J]. 临床医药文献电子杂志, 2017, 4(49):9649-9650.
[17] 李丽娜. 涤痰汤合通窍活血汤联合吞咽功能训练对脑梗死后吞咽障碍的疗效观察[J]. 陕西中医, 2016, 37(5):526-528.
[18] 吴飞虎, 朱丹华. 通窍活血汤联合脑蛋白水解物治疗气滞血瘀型突发性耳聋的临床观察[J]. 中成药, 2017,2(1):228-230.
[19] 唐爱华. 通窍活血汤加减联合针灸辨治气滞血瘀证突发性耳聋患者的临床研究[J]. 中医药学报, 2016, 44(6):78-81.
[20] 张丽娜, 孙波. 通窍活血汤联合阿司匹林对缺血性脑卒中患者氧化应激反应及神经功能缺损程度的影响[J]. 中医药导报, 2017,10(16):108-110.
[21] 高甜甜,陆惠新,钱耀华,等.通窍活血汤治疗头部外伤后早期头痛应用效果评价及分析[J].海峡药学,2016,28(1):149-150.
[22] 韩金霞.加减通窍活血汤与西药用于偏头痛治疗中的临床效果[J].北方药学,2017,14(2):30-31.
[23] 董冰.中药加味通窍活血汤治疗瘀血型偏头痛患者的临床研究[J].中西医结合心血管病电子杂志,2016,4(10):116-117.
[24] 吕山木.通窍活血汤联合窄谱中波紫外线治疗口腔扁平苔癣的临床效果[J].中国社区医师,2016,32(3):96-97.
[25] 吴思平,宋丽君.通窍活血汤加味治疗外伤性颅内血肿[J].现代中西医结合杂志,2006,15(2):214.
[2] 魏宁, 张强, 刘曼. 甘草泻心汤联合窄谱中波紫外线及西药治疗口腔糜烂型扁平苔藓疗效观察[J]. 现代中西医结合杂志, 2016, 25(24):2667-2669.
[3] 孙文晛, 阎慧军, 温莹. 白疕汤2号联合窄谱中波紫外线治疗银屑病的临床研究[J]. 中国社区医师, 2017, 33(11):78.
[4] 许芸. 窄谱中波紫外线联合退白汤治疗寻常型白癜风59例临床评价[J]. 中国药业, 2017, 26(18):45-47.
[5] 裴宇, 万军. 药物联合窄谱中波紫外线光疗治疗寻常型斑块状银屑病的疗效观察[J]. 中国处方药, 2017, 15(12):13-14.
[6] 吕慧青, 郑玮清, 颜晓波. 凉血通络汤联合窄谱中波紫外线(NB_UVB)治疗寻常型银屑病[C]. 中华中医药学会亚健康分会换届选举会议暨全国亚健康+与移动医疗融合应用学术大会, 2016.
[7] 宋红霞, 薛晓东. 消银汤联合窄谱中波紫外线治疗寻常型银屑病血热证疗效及其对外周血IL-17,IL-23,IL-6水平的影响[J]. 中国实验方剂学杂志, 2016,3(5):192-196.
[8] 卢丹, 张堃芳, 龚大范,等. 思连康联合三联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎的疗效观察[J]. 中国现代药物应用, 2016, 10(9):6-7.
[9] 宋红霞, 薛晓东. 消银汤联合窄谱中波紫外线治疗寻常型银屑病血热证疗效及其对外周血IL-17,IL-23,IL-6水平的影响[J]. 中国实验方剂学杂志, 2016,3(5):192-196.
[10] 何丽, 张静, 蔡家庆. 双歧杆菌四联活菌片联合含铋四联疗法对幽门螺杆菌感染性消化溃疡的效果分析[J]. 医学理论与实践, 2016, 29(8):1048-1050.
[11] 吴琼. 桃红四物汤加减联合NB-UVB治疗银屑病气滞血瘀证的临床疗效及对IL-4、IL-22的研究[D]. 济南:山东中医药大学, 2016.
[12] 杨刚. 青蒿鳖甲汤加减治疗结节性痒疹临床疗效观察[D]. 南京:南京中医药大学, 2017.
[13] 高琪, 杜勇, 陈惠珍. 中医辨证治疗联合康复新液含漱治疗口腔扁平苔藓患者的临床研究[J]. 辽宁中医杂志, 2016,43(8):1649-1651.
[14] 张红新. 含铋四联疗法联合双歧杆菌四联活菌片治疗幽门螺杆菌感染消化性溃疡[J]. 青岛医药卫生, 2017, 49(5):342-344.
[15] 刘运龙. 银杏达莫注射液、依达拉奉联合半夏白术天麻汤、通窍活血汤治疗急性脑梗塞128例临床分析[J]. 北方药学, 2017, 14(8):37.
[16] 朱海平. 银杏达莫注射液、依达拉奉联合半夏白术天麻汤通窍活血汤治疗急性脑梗塞128例临床分析[J]. 临床医药文献电子杂志, 2017, 4(49):9649-9650.
[17] 李丽娜. 涤痰汤合通窍活血汤联合吞咽功能训练对脑梗死后吞咽障碍的疗效观察[J]. 陕西中医, 2016, 37(5):526-528.
[18] 吴飞虎, 朱丹华. 通窍活血汤联合脑蛋白水解物治疗气滞血瘀型突发性耳聋的临床观察[J]. 中成药, 2017,2(1):228-230.
[19] 唐爱华. 通窍活血汤加减联合针灸辨治气滞血瘀证突发性耳聋患者的临床研究[J]. 中医药学报, 2016, 44(6):78-81.
[20] 张丽娜, 孙波. 通窍活血汤联合阿司匹林对缺血性脑卒中患者氧化应激反应及神经功能缺损程度的影响[J]. 中医药导报, 2017,10(16):108-110.
[21] 高甜甜,陆惠新,钱耀华,等.通窍活血汤治疗头部外伤后早期头痛应用效果评价及分析[J].海峡药学,2016,28(1):149-150.
[22] 韩金霞.加减通窍活血汤与西药用于偏头痛治疗中的临床效果[J].北方药学,2017,14(2):30-31.
[23] 董冰.中药加味通窍活血汤治疗瘀血型偏头痛患者的临床研究[J].中西医结合心血管病电子杂志,2016,4(10):116-117.
[24] 吕山木.通窍活血汤联合窄谱中波紫外线治疗口腔扁平苔癣的临床效果[J].中国社区医师,2016,32(3):96-97.
[25] 吴思平,宋丽君.通窍活血汤加味治疗外伤性颅内血肿[J].现代中西医结合杂志,2006,15(2):214.