中药浴足联合滋补肝肾潜阳颗粒治疗顽固性高血压临床疗效评价
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摘要
目的:观察中药浴足联合滋补肝肾潜阳颗粒治疗顽固性高血压的临床疗效。方法:采用随机对照双盲方法,将108例高血压患者分为治疗组和对照组,治疗组分为治疗1组和治疗2组,各36例,对照组36例。对照组给予常规西药降压药物治疗,治疗1组给予滋补肝肾潜阳颗粒+常规西药降压药物治疗,治疗2组给予滋补肝肾潜阳颗粒+常规西药降压药物治疗基础上加中药浴足治疗顽固性高血压。观察治疗前后血压变化、临床疗效及不良反应。结果:连续治疗4周后,治疗组总有效率高于对照组(P <0.05);治疗后血压与本组治疗前比较差异均存在统计学意义(P均<0.05);治疗后治疗组与对照组血压差异有统计学意义(P <0.05);中医证候疗效比较,治疗组总有效率高于对照组(P <0.05),无不良反应发生。结论:中药浴足配合滋补肝肾潜阳颗粒治疗顽固性高血压疗效满意,且不增加不良反应。
Objective: To observe the clinical efficacy of TCM medicine bathing foot plus the Zibu Ganshen Qianyang granules( 滋补肝肾潜阳颗粒) on resistant hypertension. Methods: 108 patients were divided into the treatment group 1, the treatment group 2 and the control group. The control group was given conventional western antihypertensive medicine; the treatment group 1 was treated with the Zibu Ganshen Qianyang granules plus conventional western antihypertensive medicine; the treatment group 2 was given TCM medicine bathing foot more. The changes of blood pressure, clinical efficacy and adverse reaction were observed before and after treatment. Results: The total efficiency in the treatment group was higher than the control group(P<0.05). There was a significant difference in blood pressure between before and after treatment in all groups(P<0.05). There was a significant difference in blood pressure between the treatment group and control group after treatment(P<0.05). Comparison TCM syndrome, the total efficiency in the treatment group was higher than the control group(P<0.05), without adverse reaction occurred. Conclusion: TCM medicine bathing foot plus the Zibu Ganshen Qianyang granule on resistant hypertension is satisfactory, and does not increase the adverse reaction.
Objective: To observe the clinical efficacy of TCM medicine bathing foot plus the Zibu Ganshen Qianyang granules( 滋补肝肾潜阳颗粒) on resistant hypertension. Methods: 108 patients were divided into the treatment group 1, the treatment group 2 and the control group. The control group was given conventional western antihypertensive medicine; the treatment group 1 was treated with the Zibu Ganshen Qianyang granules plus conventional western antihypertensive medicine; the treatment group 2 was given TCM medicine bathing foot more. The changes of blood pressure, clinical efficacy and adverse reaction were observed before and after treatment. Results: The total efficiency in the treatment group was higher than the control group(P<0.05). There was a significant difference in blood pressure between before and after treatment in all groups(P<0.05). There was a significant difference in blood pressure between the treatment group and control group after treatment(P<0.05). Comparison TCM syndrome, the total efficiency in the treatment group was higher than the control group(P<0.05), without adverse reaction occurred. Conclusion: TCM medicine bathing foot plus the Zibu Ganshen Qianyang granule on resistant hypertension is satisfactory, and does not increase the adverse reaction.
引文
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[7]钱锋,马英传,张晓华.滋补肝肾潜阳方治疗高血压病的临床研究中医临床研究[J].2016,8(15):49-50,52.
[2]孙宁玲,霍勇,王继光.难治性高血压诊断治疗中国专家共识[J].中华血压杂志,2013,4(11):321-326.
[3]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:74-77.
[4]孙宁玲.高血压(5)顽固性高血压的评估及治疗进展(续完)[J].中国循环杂志,2012,27(4):251-253.
[5]张伯礼.中医内科学[M].北京:人民卫生出版社,2012:117-124.
[6]陈曦,程广书,王玉民.原发性高血压病中医流行病学分析[J].医药论坛杂志,2003,24(15):58.
[7]钱锋,马英传,张晓华.滋补肝肾潜阳方治疗高血压病的临床研究中医临床研究[J].2016,8(15):49-50,52.