亲毛囊性蕈样肉芽肿误诊为毛发红糠疹1例
|
摘要
患者男,58岁。头面部、躯干及四肢红斑、鳞屑伴瘙痒1年。曾误诊为毛发红糠疹并给予治疗无效。3个月前因头部出现浸润性结节,遂再次就诊行皮肤活检、流式细胞及免疫组化检查,诊断为亲毛囊性蕈样肉芽肿。予以干扰素+维A酸胶囊+复方甘草酸苷胶囊+依巴斯汀片+曲氯乳膏方案治疗,治疗过程中行全身检查未见明显异常,目前病情基本控制,仍在随访中。
A 58-year-old male patient snffered from erythema and scales in head and face,trunk and limbs with itching for one year. He was misdiagnosed as red pityriasis,and the treatment was invalid. Three months ago,due to invasive nodules on the head,he was treated again in our hospital for skin biopsy,flow and immunohistochemistry. Profollicular mycosis fungoides was diagnosed. The combination of interferon,vitamin A acid capsule,compound glycyrrhizin capsule,Ebastine tablets,chloro chloride cream was the treatment. No obvious abnormalities in systemic examination during the treatment,thecurrent condition was basically controlled,and he was still under follow-up.
A 58-year-old male patient snffered from erythema and scales in head and face,trunk and limbs with itching for one year. He was misdiagnosed as red pityriasis,and the treatment was invalid. Three months ago,due to invasive nodules on the head,he was treated again in our hospital for skin biopsy,flow and immunohistochemistry. Profollicular mycosis fungoides was diagnosed. The combination of interferon,vitamin A acid capsule,compound glycyrrhizin capsule,Ebastine tablets,chloro chloride cream was the treatment. No obvious abnormalities in systemic examination during the treatment,thecurrent condition was basically controlled,and he was still under follow-up.
引文
[1]Muniesa C,Estrach T,Pujol RM,et al.Folloculotropic mycosis fungoides:clinicopathological features and outcome in a series of 20 cases[J].J Am Acad Dermatol,2010,62(3):418-426.
[2]Wieser I,Wang C,Alberti-Violetti S,et al.Clinical characteristics,risk factors and long-term outcome of 114 patients with folliculotropic mycosis fungoides[J].Arch Dermatol Res,2017,309(6):453-459.
[3]Jean LB,Joseph LJ,Ronald PR,et al;朱学骏,王宝玺,孙建方,等主译.皮肤病学[M].北京:北京大学医学出版社,2015:2054-2056.
[4]Hodak E,Amitay-Laish I,Atzmony L,et al.New insights into folliculotropic mycosis fungoides(FMF):a single-center experience[J].J Am Acad Dermatol,2016,75(2):347-355.
[5]Benton EC,Crichton S,Talpur R,et al.A cutaneous lymphoma international prognostic index(CLIPi)for mycosis fungoides and Sezary syndrome[J].Eur J Cancer,2013,49(13):2859-2868.
[6]Hodak E,Amitay-Laish I,Atzmony L,et al.New insights into folliculotropic mycosis fungoides(FMF):a single-center experience[J].J Am Acad Dermatol,2016,75(2):347-355.
[7]Lallas A,Apalla Z,Lefaki I,et al.Dermoscopy of early stage mycosisfungoides[J].J Eur Acad Dermatol Venereol,2013,27(5):617-621.
[8]Wilcox RA.Cutaneous T-cell lymphoma:2016 update on diagnosis,risk-stratification,andmanagement[J].Am J Hematol,2016,91(1):151-165.
[9]Olsen EA,Hodak E,Anderson T,et al.Guidelines for phototherapy of mycosis fungoides and Sezary syndrome:a consensus statement of the United States Cutaneous Lymphoma Consortium[J].J Am Acad Dermatol,2016,74(1):27-58.
[10]Gerami P,Rosen S,Kuzel T,et al.Folliculotropic mycosis fungoides:an aggressive variant of cutaneous T-cell lymphoma[J].Arch Dermatol,2008,144(6):738-746.
[11]Bar-Sela G,Bergman R.Completeregression of mycosis fungoides afteripilimumab therapy for advanced melanoma[J].JAAD Case Rep,2015,1(2):99-100.
[12]van Santen S,van Doorn R,Neelis KJ,et al.Recommendations for treatment in folliculotropic mycosis fungoides:report of the Dutch Cutaneous Lymphoma Group[J].Br J Dermatol,2017,177(1):223-228.
[13]Thomas TO,Agrawal P,Guitart J,et al.Outcome of patients treated with a single-fraction dose of palliative radiation for cutaneous T-cell lymphoma[J].Int J Radiat Oncol Biol Phys,2013,85(3):747-753.
[14]van Santen S,Maarten H,Willemze VR.Classification and recommended treatment options for folliculotropic mycosis fungoides[J].Expert Opinion on Orphan Drugs,2018,6(1):35-45.
[15]Virmani P,Zain J,Rosen ST,et al.Hematopoietic stem cell transplant for mycosis fungoides and sezary syndrome[J].Dermatol Clin,2015,33(4):807-818.
[16]Lallas A,Apalla Z,Karteridou A,et al.Photolettertotheeditor:dermoscopy for discriminating between pityriasis rubra pilaris andpsoriasis[J].J Dermatol Case Rep,2013,7(1):20-22.
[17]Marschalko M,Eros N,Kontar O,et al.Folliculotropic mycosis fungoides:clinicopathological analysis of 17 patients[J].J Eur Acad Dermatol Venereol,2015,29(5):964-972.
[2]Wieser I,Wang C,Alberti-Violetti S,et al.Clinical characteristics,risk factors and long-term outcome of 114 patients with folliculotropic mycosis fungoides[J].Arch Dermatol Res,2017,309(6):453-459.
[3]Jean LB,Joseph LJ,Ronald PR,et al;朱学骏,王宝玺,孙建方,等主译.皮肤病学[M].北京:北京大学医学出版社,2015:2054-2056.
[4]Hodak E,Amitay-Laish I,Atzmony L,et al.New insights into folliculotropic mycosis fungoides(FMF):a single-center experience[J].J Am Acad Dermatol,2016,75(2):347-355.
[5]Benton EC,Crichton S,Talpur R,et al.A cutaneous lymphoma international prognostic index(CLIPi)for mycosis fungoides and Sezary syndrome[J].Eur J Cancer,2013,49(13):2859-2868.
[6]Hodak E,Amitay-Laish I,Atzmony L,et al.New insights into folliculotropic mycosis fungoides(FMF):a single-center experience[J].J Am Acad Dermatol,2016,75(2):347-355.
[7]Lallas A,Apalla Z,Lefaki I,et al.Dermoscopy of early stage mycosisfungoides[J].J Eur Acad Dermatol Venereol,2013,27(5):617-621.
[8]Wilcox RA.Cutaneous T-cell lymphoma:2016 update on diagnosis,risk-stratification,andmanagement[J].Am J Hematol,2016,91(1):151-165.
[9]Olsen EA,Hodak E,Anderson T,et al.Guidelines for phototherapy of mycosis fungoides and Sezary syndrome:a consensus statement of the United States Cutaneous Lymphoma Consortium[J].J Am Acad Dermatol,2016,74(1):27-58.
[10]Gerami P,Rosen S,Kuzel T,et al.Folliculotropic mycosis fungoides:an aggressive variant of cutaneous T-cell lymphoma[J].Arch Dermatol,2008,144(6):738-746.
[11]Bar-Sela G,Bergman R.Completeregression of mycosis fungoides afteripilimumab therapy for advanced melanoma[J].JAAD Case Rep,2015,1(2):99-100.
[12]van Santen S,van Doorn R,Neelis KJ,et al.Recommendations for treatment in folliculotropic mycosis fungoides:report of the Dutch Cutaneous Lymphoma Group[J].Br J Dermatol,2017,177(1):223-228.
[13]Thomas TO,Agrawal P,Guitart J,et al.Outcome of patients treated with a single-fraction dose of palliative radiation for cutaneous T-cell lymphoma[J].Int J Radiat Oncol Biol Phys,2013,85(3):747-753.
[14]van Santen S,Maarten H,Willemze VR.Classification and recommended treatment options for folliculotropic mycosis fungoides[J].Expert Opinion on Orphan Drugs,2018,6(1):35-45.
[15]Virmani P,Zain J,Rosen ST,et al.Hematopoietic stem cell transplant for mycosis fungoides and sezary syndrome[J].Dermatol Clin,2015,33(4):807-818.
[16]Lallas A,Apalla Z,Karteridou A,et al.Photolettertotheeditor:dermoscopy for discriminating between pityriasis rubra pilaris andpsoriasis[J].J Dermatol Case Rep,2013,7(1):20-22.
[17]Marschalko M,Eros N,Kontar O,et al.Folliculotropic mycosis fungoides:clinicopathological analysis of 17 patients[J].J Eur Acad Dermatol Venereol,2015,29(5):964-972.