苓桂术甘汤加味治疗慢性心力衰竭的效果
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摘要
目的:探究对慢性心力衰竭患者实施苓桂术甘汤加味治疗的效果,为临床提供指导。方法:选取2015年1月-2017年12月本院收治的60例慢性心力衰竭患者。按照随机数字表法将其分为观察组(常规西医治疗+苓桂术甘汤加味治疗)和对照组(常规西医治疗),各30例。随访1年,比较两组疗效、心功能指标(LVEDD、LVESD、LVEF、CI、CO、SV)、生活质量评分、反复住院次数、平均每次住院时间、平均每次住院费用。结果:观察组总有效率为93.33%,高于对照组的73.33%(P<0.05);治疗后,观察组LVEDD、LVESD均小于对照组,LVEF、CI、CO、SV均高于对照组,比较差异均有统计学意义(P<0.05);观察组治疗后各项生活质量评分均高于对照组(P<0.05);观察组反复住院次数、平均每次住院时间、平均每次住院费用均少于对照组(P<0.05)。结论:对慢性心力衰竭患者实施苓桂术甘汤加味治疗十分可行,不仅有助于增强疗效,改善患者心功能及生活质量,还有助于减少住院次数及住院时间,对减轻患者家庭经济负担有较积极的影响。
Objective:To explore the effect of Lingguizhugan Decoction on patients with chronic heart failure.Method:A total of 60 patients with chronic heart failure in our hospital from January 2015 to December 2017 were selected.According to the random number table method,they were divided into observation group(conventional western medicine treatment+Lingguizhugan Decoction modified treatment)and control group(conventional western medicine treatment),30 cases in each group.The curative effect,cardiac function index(LVEDD,LVESD,LVEF,CI,CO,SV),quality of life score,repeated hospitalization times,average hospitalization time and average hospitalization cost between two groups were compared.Result:The total effective rate was 93.33% in observation group,which was higher than 73.33%in control group(P<0.05).After treatment,the LVEDD and LVESD in observation group were lower than those of control group,and the LVEF,CI,CO and SV in observation group were higher than those of control group,the differences were statistically significant(P<0.05).After treatment,the each score of quality of life in observation group were higher than those of control group(P<0.05).The number of repeated hospitalizations,average hospitalization time and average hospitalization expenses in observation group were less than those of control group(P<0.05).Conclusion:It is very feasible to treat patients with chronic heart failure with Lingguizhugan Decoction,which can not only enhance the curative effect,improve the heart function and quality of life,but also reduce the number of hospital stay and the length of hospitalization,it has a positive effect on reducing the economic burden of the patient's family.
Objective:To explore the effect of Lingguizhugan Decoction on patients with chronic heart failure.Method:A total of 60 patients with chronic heart failure in our hospital from January 2015 to December 2017 were selected.According to the random number table method,they were divided into observation group(conventional western medicine treatment+Lingguizhugan Decoction modified treatment)and control group(conventional western medicine treatment),30 cases in each group.The curative effect,cardiac function index(LVEDD,LVESD,LVEF,CI,CO,SV),quality of life score,repeated hospitalization times,average hospitalization time and average hospitalization cost between two groups were compared.Result:The total effective rate was 93.33% in observation group,which was higher than 73.33%in control group(P<0.05).After treatment,the LVEDD and LVESD in observation group were lower than those of control group,and the LVEF,CI,CO and SV in observation group were higher than those of control group,the differences were statistically significant(P<0.05).After treatment,the each score of quality of life in observation group were higher than those of control group(P<0.05).The number of repeated hospitalizations,average hospitalization time and average hospitalization expenses in observation group were less than those of control group(P<0.05).Conclusion:It is very feasible to treat patients with chronic heart failure with Lingguizhugan Decoction,which can not only enhance the curative effect,improve the heart function and quality of life,but also reduce the number of hospital stay and the length of hospitalization,it has a positive effect on reducing the economic burden of the patient's family.
引文
[1]王艳,周萍.金匮肾气丸合苓桂术甘汤加味治疗肺心病伴右心衰竭临床研究[J].陕西中医,2017,38(5):581-582.
[2]李克营,杨芳.苓桂术甘配方颗粒治疗慢性心力衰竭(心肾阳虚证)的临床观察[J].湖南中医药大学学报,2017,37(8):895-899.
[3]徐永良.苓桂术甘汤加味治疗慢性心力衰竭临床效果观察[J].内蒙古中医药,2017,36(20):74-75.
[4]陈少旭,梁小银,侯晓亮,等.苓桂术甘汤配方颗粒加味治疗慢性射血分数降低心力衰竭的临床观察[J].光明中医,2018,33(8):1104-1107.
[5]杨潮,李雪萍,魏蜀君,等.苓桂术甘汤加减联合西医治疗对慢性心力衰竭患者炎性因子、T淋巴细胞亚群及心功能的影响[J].中国免疫学杂志,2018,34(7):1001-1005.
[6]任中钧.袁海波教授治疗心水病(慢性收缩性心力衰竭)用药规律研究[D].郑州:河南中医学院,2015.
[7]裴泽方,亢晓红,王领倩,等.真武苈苓汤加减联合西医常规治疗慢性肺源性心脏病50例[J].中医研究,2015,28(11):18-20.
[8]隋世华,蔡雪峰.苓桂术甘汤配合曲美他嗪对缺血性心肌病慢性心力衰竭患者心功能的影响[J].现代中西医结合杂志,2017,26(20):2214-2216.
[9]杨环,高积慧.康复运动联合加味苓桂术甘汤对心力衰竭大鼠Cys-C及心室重构的影响[J].湖南中医杂志,2017,33(5):152-155.
[10]王少明,田新利.苓桂术甘汤加减联合西药治疗慢性心力衰竭的疗效及对心功能的影响[J].中国急救医学,2016,36(z1):125-126.
[11]曾传林,郭燕,孙琳林,等.苓桂术甘汤治疗心力衰竭的研究进展[J].牡丹江医学院学报,2018,39(2):98-100.
[12]肖加斌,刘媛.真武汤合苓桂术甘汤联合西医常规疗法治疗老年心功能衰竭临床研究[J].国际中医中药杂志,2017,39(7):583-586.
[13]许晓梅.加味苓桂术甘汤对老年慢性心力衰竭患者脑钠肽及心功能的影响[J].中国中医药现代远程教育,2017,15(15):108-109,118.
[14]卢玉俊,滕政杰,崔庆荣,等.基于中医传承辅助系统分析曹玉山治疗慢性心力衰竭用药经验[J].山西中医,2016,32(1):47-50.
[15]王欢,蔡珠虹,侯增霞,等.益气活血复方通过自噬调控心力衰竭大鼠心肌能量代谢的研究[J].中国中西医结合急救杂志,2018,25(5):529-533.
[16]周鹏,黄金玲.苓桂术甘汤防治慢性心力衰竭的临床应用及药理作用研究进展[J].时珍国医国药,2018,29(9):2231-2233.
[17]赵明.苓桂术甘汤治疗慢性心力衰竭患者的临床效果[J].光明中医,2016,31(19):2827-2829.
[18]乔玉冰,向东,肖应东.苓桂术甘汤结合参麦注射液治疗慢性心力衰竭临床观察[J].中医药导报,2015,21(3):83-85.
[19]贺清.加味苓桂术甘汤治疗慢性心力衰竭(心肾阳虚型)的临床观察[D].武汉:湖北中医药大学,2016.
[20]张国芳,张玉芝,栗晓乐.苓桂术甘汤加减治疗慢性心力衰竭的疗效观察[J].中医临床研究,2017,9(5):34-35.
[2]李克营,杨芳.苓桂术甘配方颗粒治疗慢性心力衰竭(心肾阳虚证)的临床观察[J].湖南中医药大学学报,2017,37(8):895-899.
[3]徐永良.苓桂术甘汤加味治疗慢性心力衰竭临床效果观察[J].内蒙古中医药,2017,36(20):74-75.
[4]陈少旭,梁小银,侯晓亮,等.苓桂术甘汤配方颗粒加味治疗慢性射血分数降低心力衰竭的临床观察[J].光明中医,2018,33(8):1104-1107.
[5]杨潮,李雪萍,魏蜀君,等.苓桂术甘汤加减联合西医治疗对慢性心力衰竭患者炎性因子、T淋巴细胞亚群及心功能的影响[J].中国免疫学杂志,2018,34(7):1001-1005.
[6]任中钧.袁海波教授治疗心水病(慢性收缩性心力衰竭)用药规律研究[D].郑州:河南中医学院,2015.
[7]裴泽方,亢晓红,王领倩,等.真武苈苓汤加减联合西医常规治疗慢性肺源性心脏病50例[J].中医研究,2015,28(11):18-20.
[8]隋世华,蔡雪峰.苓桂术甘汤配合曲美他嗪对缺血性心肌病慢性心力衰竭患者心功能的影响[J].现代中西医结合杂志,2017,26(20):2214-2216.
[9]杨环,高积慧.康复运动联合加味苓桂术甘汤对心力衰竭大鼠Cys-C及心室重构的影响[J].湖南中医杂志,2017,33(5):152-155.
[10]王少明,田新利.苓桂术甘汤加减联合西药治疗慢性心力衰竭的疗效及对心功能的影响[J].中国急救医学,2016,36(z1):125-126.
[11]曾传林,郭燕,孙琳林,等.苓桂术甘汤治疗心力衰竭的研究进展[J].牡丹江医学院学报,2018,39(2):98-100.
[12]肖加斌,刘媛.真武汤合苓桂术甘汤联合西医常规疗法治疗老年心功能衰竭临床研究[J].国际中医中药杂志,2017,39(7):583-586.
[13]许晓梅.加味苓桂术甘汤对老年慢性心力衰竭患者脑钠肽及心功能的影响[J].中国中医药现代远程教育,2017,15(15):108-109,118.
[14]卢玉俊,滕政杰,崔庆荣,等.基于中医传承辅助系统分析曹玉山治疗慢性心力衰竭用药经验[J].山西中医,2016,32(1):47-50.
[15]王欢,蔡珠虹,侯增霞,等.益气活血复方通过自噬调控心力衰竭大鼠心肌能量代谢的研究[J].中国中西医结合急救杂志,2018,25(5):529-533.
[16]周鹏,黄金玲.苓桂术甘汤防治慢性心力衰竭的临床应用及药理作用研究进展[J].时珍国医国药,2018,29(9):2231-2233.
[17]赵明.苓桂术甘汤治疗慢性心力衰竭患者的临床效果[J].光明中医,2016,31(19):2827-2829.
[18]乔玉冰,向东,肖应东.苓桂术甘汤结合参麦注射液治疗慢性心力衰竭临床观察[J].中医药导报,2015,21(3):83-85.
[19]贺清.加味苓桂术甘汤治疗慢性心力衰竭(心肾阳虚型)的临床观察[D].武汉:湖北中医药大学,2016.
[20]张国芳,张玉芝,栗晓乐.苓桂术甘汤加减治疗慢性心力衰竭的疗效观察[J].中医临床研究,2017,9(5):34-35.