神阙敷贴法治疗血瘀型原发性痛经疗效观察
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摘要
目的观察神阙敷贴法治疗血瘀型原发性痛经的临床疗效。方法选取60例血瘀型原发性痛经患者,随机分为治疗组和对照组,两组分别于月经前3天开始治疗,治疗组采用中药敷贴神阙,对照组予布洛芬缓释胶囊口服,连续治疗3个月经周期,分别于治疗前、治疗后、随访期记录痛经积分及中医血瘀症候情况,观察两组临床疗效变化。结果治疗组近期总有效率为93.3%,稍低于对照组总有效率的96.7%,而治疗组远期疗效(93.3%)明显高于对照组(50.0%)。治疗组血瘀症候变化明显高于对照组,尤其在月经量、月经不畅、血色、血块等方面变化显著(P<0.01)。两组患者治疗期间均无不良反应发生。结论神阙敷贴疗法能够有效缓解痛经,改善痛经血瘀证型的临床症状。
Objective To observe the clinical efficacy of application at Shenque(CV8) in treating primary dysmenorrhea due to blood stagnation. Method Sixty patients with primary dysmenorrhea due to blood stagnation were enrolled and randomized into a treatment group and a control group to receive the corresponding intervention, started 3 d prior to menstruation. The treatment group was intervened by application at Shenque with Chinese herbal medicine while the control group was by orally taking Ibuprofen sustained release capsules, successively for 3 menstrual cycles. The pre-treatment, short-term and follow-up dysmenorrhea scores and traditional Chinese medicine symptom and sign scores for blood stagnation were recorded, and the clinical efficacies of the two groups were observed. Result The short-term total effective rate was 93.3% in the treatment group, slightly lower than 96.7% in the control group, while the long-term therapeutic efficacy in the treatment group(93.3%) was obviously higher than that in the control group(50.0%). The changes in the symptom and sign scores for blood stagnation in the treatment group were more significant than those in the control group, especially in the scores of menstruation amount, blocked menstrual flow, color of menstrual blood and blood clots(P<0.01). No adverse events occurred during the whole study. Conclusion Application at Shenque can effectively release menstrual pain and improve the symptoms of dysmenorrhea due to blood stagnation.
Objective To observe the clinical efficacy of application at Shenque(CV8) in treating primary dysmenorrhea due to blood stagnation. Method Sixty patients with primary dysmenorrhea due to blood stagnation were enrolled and randomized into a treatment group and a control group to receive the corresponding intervention, started 3 d prior to menstruation. The treatment group was intervened by application at Shenque with Chinese herbal medicine while the control group was by orally taking Ibuprofen sustained release capsules, successively for 3 menstrual cycles. The pre-treatment, short-term and follow-up dysmenorrhea scores and traditional Chinese medicine symptom and sign scores for blood stagnation were recorded, and the clinical efficacies of the two groups were observed. Result The short-term total effective rate was 93.3% in the treatment group, slightly lower than 96.7% in the control group, while the long-term therapeutic efficacy in the treatment group(93.3%) was obviously higher than that in the control group(50.0%). The changes in the symptom and sign scores for blood stagnation in the treatment group were more significant than those in the control group, especially in the scores of menstruation amount, blocked menstrual flow, color of menstrual blood and blood clots(P<0.01). No adverse events occurred during the whole study. Conclusion Application at Shenque can effectively release menstrual pain and improve the symptoms of dysmenorrhea due to blood stagnation.
引文
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[22]辛思源,张鹏,林驰,等.从经脉脏腑角度探讨痛经病位胞宫与经穴效应的关系[J].中华中医药学刊,2015,(8):1883-1887.
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[25]马会敏.少腹逐瘀汤联合熨烫疗法治疗原发性痛经32例[J].中医临床研究,2014,6(23):109.
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[27]佘延芬,孙立虹,杨继军,等.隔物灸对寒湿凝滞型原发性痛经患者经期血浆β-EP含量的影响[J].中国针灸,2008,28(10):719-721.
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[29]王佳,王昕.中医药治疗原发性痛经简况[J].实用中医内科杂志,2016,(3):104-105.
[30]崔丹,王翠霞.王翠霞辨证论治痛经[J].实用中医内科杂志,2016,(3):22-24.
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[33]唐英,周立华.艾灸关元、神阙、足三里治疗艾滋病脾气虚腹泻的特异性效应研究初探[J].中医研究,2007,(9):56-58.
[34]王倩,汪慧敏.麝香贴敷神阙穴治疗重度痛经的临床疗效观察[J].浙江中医学院学报,2004,28(4):66.
[35]金影,刘震坤.中药外敷神阙穴治疗原发性痛经66例疗效观察[J].中国社区医师,2008,24(8):51.
[36]宋昌红.愈痛贴治疗寒湿凝滞型痛经临床疗效观察[J].四川中医,2005,23(7):82-83.
[37]段东印.中药酊剂神阙穴外涂治疗婴幼儿腹泻30例[J].实用儿科临床杂志,2003,18(10):850-851.
[38]薛秋芬,刘长君.中药外敷神阙穴治疗术后腹胀临床观察[J].现代中医药,2007,27(5):72-73.
[2]黄艳.血府逐瘀汤加味治疗原发性痛经的疗效观察[J].中医药信息,2014,31(2):95-96.
[3]艾文超,李松梅,朴晋华.丁桂儿脐贴治疗寒凝血瘀型痛经的实验研究[J].山西中医,2010,26(6):50-52,54.
[4]刘雅嫒,何贵翔.中医药治疗寒凝血瘀型原发性痛经的研究进展[J].中华实用中西医杂志,2007,20(6):539-540.
[5]彭爱东.中药三七片对原发性痛经的疗效[J].中国保健营养(下半月),2013,(7):2098.
[6]张建林.中药活血止痛汤治疗妇科痛经急症临床疗效分析[J].西藏医药,2016,37(2):83-84.
[7]周春晓.中药加艾灸治疗原发性痛经的效果比较[J].现代养生,2014,(16):234.
[8]吴青青.温针灸治疗原发性青春期痛经的疗效分析[J].中国保健营养(下半月),2013,(5):1503-1504.
[9]高汉媛,赵耀东,惠建萍,等.针灸治疗痛经47例的临床疗效观察[J].卫生职业教育,2006,(6):151-152.
[10]焦富莲,梁永翠,何敏,等.针灸治疗原发性痛经疗效观察[J].上海针灸杂志,2014,33():414-415.
[11]陈文,俞海虹,刘世红,等.穴位埋线治疗原发性痛经的疗效观察[J].浙江中医药大学学报,2012,36(8):924-926.
[12]王明明,杨颖.穴位埋线治疗寒凝血瘀型原发性痛经临床观察[J].广西中医药大学学报,2014,17(3):8-9.
[13]刘俊宏,吴志敏,徐占一.穴位埋线治疗原发性痛经35例[J].上海针灸杂志,2014,33(4):362.
[14]吕庆超,高树中.巴布贴敷脐治疗原发性痛经临床观察[J].中国针灸,2007,27(S1):67-69.
[15]乐杰.妇产科学[M].第7版,北京:人民卫生出版社,2008:318.
[16]国家中医药管理局.中医病证诊断疗效标准[S].南京:南京大学出版社,1994:61-62.
[17]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:241.
[18]司徒仪,杨家林.妇科专病中医临床诊治[M].北京:人民卫生出版社,2001:4.
[19]邓海霞,朱南孙,王采文,等.加味没竭片对原发性痛经患者经期血浆催产素的影响[J].中国中西医结合杂志,2003,23(5):354-356.
[20]韩蓁,张明慧.原发性痛经病因研究进展[J].国外医学(妇幼保健分册),1997,8(1):1-2.
[21]嵇波,任晓暄,赵雅芳,等.原发性痛经发病机制与预防研究评述[J].中国现代医学杂志,2008,18(13):1856-1858.
[22]辛思源,张鹏,林驰,等.从经脉脏腑角度探讨痛经病位胞宫与经穴效应的关系[J].中华中医药学刊,2015,(8):1883-1887.
[23]尹毅,杨丽,任辉,等.原发性痛经的辨证治疗与护理[J].中华临床医学杂志,2007,8(1):91-92.
[24]张鸿宇,王鸿度.温针灸治疗痛经的临床研究概况[J].当代医药论丛(下半月),2013,11(2):335-336.
[25]马会敏.少腹逐瘀汤联合熨烫疗法治疗原发性痛经32例[J].中医临床研究,2014,6(23):109.
[26]张晓华,方如丹,于杰.磁药敷脐治疗血淤型原发性痛经及对子宫血流动力学的影响[J].时珍国医国药,2011,22(2):365-366.
[27]佘延芬,孙立虹,杨继军,等.隔物灸对寒湿凝滞型原发性痛经患者经期血浆β-EP含量的影响[J].中国针灸,2008,28(10):719-721.
[28]刘敏如,谭万信.中医妇产科学[M].第2版,北京:人民卫生出版社,2011:344.
[29]王佳,王昕.中医药治疗原发性痛经简况[J].实用中医内科杂志,2016,(3):104-105.
[30]崔丹,王翠霞.王翠霞辨证论治痛经[J].实用中医内科杂志,2016,(3):22-24.
[31]包红桃,武权生.武权生教授运用温肾暖宫方治疗痛经经验介绍[J].新中医,2015,(12):5-6.
[32]张晓金.痛经的现代研究进展[J].陕西中医,2000,21(12):574-575.
[33]唐英,周立华.艾灸关元、神阙、足三里治疗艾滋病脾气虚腹泻的特异性效应研究初探[J].中医研究,2007,(9):56-58.
[34]王倩,汪慧敏.麝香贴敷神阙穴治疗重度痛经的临床疗效观察[J].浙江中医学院学报,2004,28(4):66.
[35]金影,刘震坤.中药外敷神阙穴治疗原发性痛经66例疗效观察[J].中国社区医师,2008,24(8):51.
[36]宋昌红.愈痛贴治疗寒湿凝滞型痛经临床疗效观察[J].四川中医,2005,23(7):82-83.
[37]段东印.中药酊剂神阙穴外涂治疗婴幼儿腹泻30例[J].实用儿科临床杂志,2003,18(10):850-851.
[38]薛秋芬,刘长君.中药外敷神阙穴治疗术后腹胀临床观察[J].现代中医药,2007,27(5):72-73.