摘要
目的:探讨与研究应用超声心动图检查肥厚型心肌病患者升主动脉弹性改变特征,分析患者升主动脉功能改变情况。方法:选择我院接受超声心动图检查的肥厚型心肌病患者作为研究对象,依据患者病变分为梗阻性组(HOCM组)和非梗阻性组(HNOCM组),并选择健康体检者作为对照组,每组30例。比较3组超声心动图参数、升主动脉弹性参数。结果:对HOCM组、HNOCM组和对照组3组分析,升主动脉应变、扩张性和舒张早期运动速度逐渐升高,升主动脉僵硬度指数则依次序下降,以上均有统计学意义(P<0.05);HOCM组和HNOCM组患者舒张晚期运动速度明显低于对照组,HOCM组升主动脉前壁收缩期运动速度低于对照组,以上差异有统计意义(P<0.05)。结论:与健康体检者相比,肥厚型心肌病患者升主动脉血管弹性下降,其中梗阻性肥厚型心肌病患者下降程度更为明显。
Objective:We investigated the characteristics of ascending aorta elasticity in patients with hypertrophic cardiomyopathy by echocardiography and analyzed the changes of ascending aortic function in patients with hypertrophic cardiomyopathy.Method:The patients with hypertrophic cardiomyopathy who received echocardiographic examination in our hospital were divided into obstructive group(HOCM group)and non-obstructive group(HNOCM group)according to the pathological changes.The healthy persons were selected as the control group.Each group had 30 cases.We compared echocardiographic parameters and ascending aortic elastic parameters among the three groups.Result:Among the HOCM group,HNOCM group and control group,the ascending aortic strain index,dilation and early diastolic velocity increased gradually,while ascending aortic stiffness index decreased,which were statistically significant(P<0.05).The late diastolic movement velocity in HOCM and HNOCM groups were significantly lower than those in control group,and the systolic velocity of ascending aortic anterior wall in HOCM group was lower than that in control group(P<0.05).Conclusion:The vascular elasticity of ascending aorta was decreased in hypertrophic cardiomyopathy patients,especially in obstructive hypertrophic cardiomyopathy patients.
引文
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