摘要
目的研究D-二聚体、动脉血乳酸、氧合指数、CRP对重症肺炎预后的影响。方法选取我院2017年3月—8月收治的重症肺炎患者40例作为观察组,另选取同时间段在我院进行体检的40例健康者为对照组。分别检测2组D-二聚体、动脉血乳酸、氧合指数、CRP值,并进行分析对比。结果对照组D-二聚体、动脉血乳酸、CRP均比观察组低,氧合指数比观察组高,差异有统计学意义(P<0.05)。结论 D-二聚体、动脉血乳酸、氧合指数、CRP与重症肺炎患者病情发展具有密切的相关性,且能够作为预后的反映指标,当其水平超过临界值后,临床应密切监测患者情况。
Objective To study the effect of D-Dimer,arterial blood lactate,oxygenation index,C-reactive protein(CRP)on prognosis of severe pneumonia. Methods 40 patients with severe pneumonia from March 2017 to August 2017 were selected as observation group,and 40 healthy controls were selected as control group at the same time.The D-Dimer,arterial blood lactate,oxygenation index,CRP of two groups were detected and compared. Results The D-Dimer,arterial blood lactate,CRP in control group were lower than those in observation group,and oxygenation index was higher than observation group(P<0.05).Conclusion D-Dimer,arterial blood lactate,oxygenation index,CRP have close correlation with progression of severe pneumonia,and they can be taken as indicators of prognosis. When their levels exceed the critical value,it is necessary to closely monitor patients' conditions to increase prognosis.
引文
[1]韩利,张筠,张铁栓.重症肺炎患者D-二聚体、纤维蛋白原、IL-6水平变化及其临床意义[J].中国呼吸与危重监护杂志,2017,16(1):71-73.
[2]刘伟,彭丽萍,华树成.动态监测重症肺炎患者血乳酸、氧合指数及C反应蛋白的临床意义[J].国际呼吸杂志,2015,35(14):1048-1051.
[3]杨日焰,陈杏波,刘汉冕,等.重症肺炎液体复苏患者乳酸清除率、氧合指数与预后相关性研究[J].临床和实验医学杂志,2016,15(12):1149-1151.
[4]王安桥.乳酸、D-二聚体及C-反应蛋白水平检测对重症肺炎的临床意义及预后价值的分析[J].广西医科大学学报,2016,33(3):479-481.
[5]莫必华,刘艳秀,甘国能,等.小潮气量机械通气治疗老年重症肺炎呼吸衰竭对动脉血气及预后的影响[J].国际老年医学杂志,2015,36(6):249-251.