自拟益气化瘀利水方治疗慢性肺源性心脏病的临床疗效观察
|
摘要
目的探讨益气化瘀利水方治疗慢性肺源性心脏病的临床疗效。方法收集符合慢性肺心病临床纳入标准的患者60例,分为治疗组和对照组,其中治疗组30例,对照组30例。治疗组30例除给予常规药物治疗外,加服益气化瘀利水方;对照组30例接受常规治疗。比较两组的临床疗效。结果治疗组治疗后的C反应蛋白(CRP)、脑利钠肽(BNP)、纤维蛋白降解产物(FDP)、动脉血氧分压(PaO_2)指标均比对照组低,且具有统计学意义(P<0.05),具有显著统计学差异(P<0.01)。结论在常规西医治疗基础上加用中药益气化瘀利水方治疗慢性肺源性心脏病,能显著改善该病的临床疗效,值得推广应用。
Objective To investigate the clinical efficacy of Yiqi Huayu Lishui Recipe in the treatment of chronic cor pulmonale. Methods Sixty patients with clinical criteria of chronic pulmonary heart disease were collected and divided into treatment group and control group, of which 30 cases in the treatment group and 30 cases in the control group. In the treatment group, 30 cases were treated with routine drug treatment plus Yiqi Huayu Li Shui Fang; Control group 30 patients underwent routine treatment. The clinical efficacy of the two groups was compared. Results After treatment, the CRP, BNP, FDP and PaO_2 in the treatment group were lower than those in the control group, and there was a significant difference(P<0.01). Conclusion The treatment of chronic cor pulmonale with traditional Chinese medicine Yiqi Huayu Lishui on the basis of conventional western medicine can significantly improve the clinical curative effect of the disease and is worth popularizing and applying.
Objective To investigate the clinical efficacy of Yiqi Huayu Lishui Recipe in the treatment of chronic cor pulmonale. Methods Sixty patients with clinical criteria of chronic pulmonary heart disease were collected and divided into treatment group and control group, of which 30 cases in the treatment group and 30 cases in the control group. In the treatment group, 30 cases were treated with routine drug treatment plus Yiqi Huayu Li Shui Fang; Control group 30 patients underwent routine treatment. The clinical efficacy of the two groups was compared. Results After treatment, the CRP, BNP, FDP and PaO_2 in the treatment group were lower than those in the control group, and there was a significant difference(P<0.01). Conclusion The treatment of chronic cor pulmonale with traditional Chinese medicine Yiqi Huayu Lishui on the basis of conventional western medicine can significantly improve the clinical curative effect of the disease and is worth popularizing and applying.
引文
[1]李丽丽.60例老年慢性阻塞性肺病合并左心衰竭的治疗体会[J].临床研究,2014,12(21):139.
[2]蔡敏,杨兴嫕,史锁芳.”益气化瘀、温阳利水方”治疗肺心病的作用机理[J].中成药,2015,37,10:2267-2271.
[3]曾桂珍,张俊.慢性肺心病急性感染加重期患者的临床治疗观察[J].中国医药指南,2013,11(36):48-49.
[4]钱群飞.卡托普利与螺内酯联合生脉注射液治疗右心衰竭合并慢性肺心病的疗效观察[J].临床合理用药杂志,2014,7(26):46-47.
[5]何雪明,黄中学.硅沉着病患者血浆二聚体测定的临床意义[J].内科,2013,8(3):213.
[6]宋丽红,程兆忠.尘肺病患者二聚体、纤维蛋白原检测意义及与C反应蛋白、白细胞介素的相关性分析[J].青岛大学硕士学位论文,2014:4-5.
[7]杨秀玲,刘新建,常程.心力衰竭患者血浆B型钠尿肽变化及临床意义[J].山东医药,2005,45(5):50-51.
[8]史晓敏,徐国宾,夏铁安.N末端B型钠尿肽原对充血性心力衰竭患者预后及危险分层评价的价值[J].中华检验医学杂志,2010,29(l):27-30.
[9]Gray JR.The use ofβ-type natriuretic peptide to diagnose congestive heart failure[J].Clin Lab Sci,2006,19(4):214-217.
[10]英殿军,何述祥,张晓兰,等.化学发光免疫分析法检测B型钠尿肽在心力衰竭诊断中的价值[J].国际检验医学杂志,2007,28(2):113-114.
[11]Sin D D,Anthonisen N R,Soriano J B,et al.Mortality in COPD:role of comorbidities[J].Eur Respir J,2006,28:1245-1257.
[12]杨红琼.血气分析在重症呼吸系统疾病中的应用[J].现代诊断与治疗,2014,25(05):1131-1132.
[13]陈雄,陈翠霞,张静,等.无创机械通气对慢性肺心病并发呼吸衰竭患者血浆BNP和ET-1水平的影响[J].中国临床新医学,2015,8(10):946-949.
[14]王东太.中西医结合治疗肺心病难治性心衰临床分析[J].内蒙古中医药,2015,34(9):35-36.
[15]胡蓉.低分子肝素辅助治疗慢性肺源性心脏病心力衰竭的临床疗效分析[J].中国医药指南,2015,13(11):54-55.
[16]杨波,寇媛.自拟益气活血汤对肺心病合并右心衰血脂、血液流变学及生存质量的影响[J].中国中医急症,2016,25(7):1432-1434.
[2]蔡敏,杨兴嫕,史锁芳.”益气化瘀、温阳利水方”治疗肺心病的作用机理[J].中成药,2015,37,10:2267-2271.
[3]曾桂珍,张俊.慢性肺心病急性感染加重期患者的临床治疗观察[J].中国医药指南,2013,11(36):48-49.
[4]钱群飞.卡托普利与螺内酯联合生脉注射液治疗右心衰竭合并慢性肺心病的疗效观察[J].临床合理用药杂志,2014,7(26):46-47.
[5]何雪明,黄中学.硅沉着病患者血浆二聚体测定的临床意义[J].内科,2013,8(3):213.
[6]宋丽红,程兆忠.尘肺病患者二聚体、纤维蛋白原检测意义及与C反应蛋白、白细胞介素的相关性分析[J].青岛大学硕士学位论文,2014:4-5.
[7]杨秀玲,刘新建,常程.心力衰竭患者血浆B型钠尿肽变化及临床意义[J].山东医药,2005,45(5):50-51.
[8]史晓敏,徐国宾,夏铁安.N末端B型钠尿肽原对充血性心力衰竭患者预后及危险分层评价的价值[J].中华检验医学杂志,2010,29(l):27-30.
[9]Gray JR.The use ofβ-type natriuretic peptide to diagnose congestive heart failure[J].Clin Lab Sci,2006,19(4):214-217.
[10]英殿军,何述祥,张晓兰,等.化学发光免疫分析法检测B型钠尿肽在心力衰竭诊断中的价值[J].国际检验医学杂志,2007,28(2):113-114.
[11]Sin D D,Anthonisen N R,Soriano J B,et al.Mortality in COPD:role of comorbidities[J].Eur Respir J,2006,28:1245-1257.
[12]杨红琼.血气分析在重症呼吸系统疾病中的应用[J].现代诊断与治疗,2014,25(05):1131-1132.
[13]陈雄,陈翠霞,张静,等.无创机械通气对慢性肺心病并发呼吸衰竭患者血浆BNP和ET-1水平的影响[J].中国临床新医学,2015,8(10):946-949.
[14]王东太.中西医结合治疗肺心病难治性心衰临床分析[J].内蒙古中医药,2015,34(9):35-36.
[15]胡蓉.低分子肝素辅助治疗慢性肺源性心脏病心力衰竭的临床疗效分析[J].中国医药指南,2015,13(11):54-55.
[16]杨波,寇媛.自拟益气活血汤对肺心病合并右心衰血脂、血液流变学及生存质量的影响[J].中国中医急症,2016,25(7):1432-1434.