长脉宽1064nm Nd:YAG激光治疗280例幼儿皮肤血管瘤疗效观察
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摘要
目的:评估长脉宽1 064nm Nd:YAG激光治疗幼儿皮肤血管瘤的疗效和不良反应。方法:使用长脉宽可调脉宽1 064nm Nd:YAG激光治疗280例1月~1岁的患者,分别选择光斑直径2mm、6mm,能量30~90J/cm2和脉宽10ms、15ms、45ms进行治疗,治疗间隔时间为1个月。结果:经1~6次治疗后,268例治愈(95.7%),9例显效(3.2%),3例有效(1.1%),有效率100%。治疗后出现3例感染,2例增生性瘢痕,5例轻度皮肤萎缩,18例轻度色素异常,但均逐渐恢复。结论:长脉宽1 064nm Nd:YAG激光治疗幼儿皮肤血管瘤疗效显著,不良反应少且短暂。
Objective To observe the curative effect and adverse reaction of long-pulsed 1 064 nm Nd:YAG laser in the treatment of infant cutaneous hemangiomas. Methods 280 patients with hemangioma from one month to one year were treated with the long-pulsed 1 064 nm Nd: YAG Iaser.Correlated parameters were as follows:spot diameter 2mm,6mm,energy density 30-90 J/cm2,pulse width(10ms,15 ms,45ms),the treatment interval was one month. Results After 1-6 treatment times, 268 cases(95.7%) obtained complete healing,9 cases(3.2%) obtained obvious fading,3 cases(1.1%) gained effective therapy,the effective rate was 100%. There were 3 cases infection,2 cases hyperplastic scar,5 cases slight adermotrophia,18 cases slight pigment alteration after the courses of treatment which can recover gradually. Conclusion The long-pulsed 1 064 nm Nd:YAG Iaser is effective and safe in the treatment of infant cutaneous hemangioma.
Objective To observe the curative effect and adverse reaction of long-pulsed 1 064 nm Nd:YAG laser in the treatment of infant cutaneous hemangiomas. Methods 280 patients with hemangioma from one month to one year were treated with the long-pulsed 1 064 nm Nd: YAG Iaser.Correlated parameters were as follows:spot diameter 2mm,6mm,energy density 30-90 J/cm2,pulse width(10ms,15 ms,45ms),the treatment interval was one month. Results After 1-6 treatment times, 268 cases(95.7%) obtained complete healing,9 cases(3.2%) obtained obvious fading,3 cases(1.1%) gained effective therapy,the effective rate was 100%. There were 3 cases infection,2 cases hyperplastic scar,5 cases slight adermotrophia,18 cases slight pigment alteration after the courses of treatment which can recover gradually. Conclusion The long-pulsed 1 064 nm Nd:YAG Iaser is effective and safe in the treatment of infant cutaneous hemangioma.
引文
[1]Mulliken JB,Glowacki J.Hemangiomas and vascular malformations in infants and children:a classification based on endothelial characteristics[J].Plast Reconstr Surg,1982,69(3):412-422.
[2]卢忠.皮肤激光医学与美容[M].上海:复旦大学出版社,2015:14,67-68.
[3]林晓曦,王炜,曹谊林.血管瘤和血管畸形治疗中的美容原则探讨[J].中华医学美学美容杂志,2003.6(9):190-192.
[4]Metka A,Agneta T,Maurice A,et a1.Vascular lasers and IPLS:Guidelines for care from the European Society for Laser Dermatology(ESLD)[J].J Cosmetic Laser Ther,2007,9(2):113-124.
[5]Wilder D.Pulsed 1 064nm Nd:YAG laser therapy for noninvasive treatment of a massive hemangioma:case report[J].J C1in Laser Med Surg,1999,17(6):245-247.
[6]Woo WK,Jasim ZF,Handley JM.532 nm Nd:YAG and 595 nm pulsed dye laser treatment of leg telangiectasia using ultralong pulse duration[J].Dermatol Surg,2003,29(12):1176-1180.
[7]黎宁,陈彦伟,池刚毅,等.强脉冲光治疗浅表(皮肤)血管瘤临床观察[J].中国美容医学,2007.16(6):792-794.
[8]刘盛秀,杨春俊,杨森,等.595 nm可调脉冲染料激光治疗皮肤血管异常性疾病疗效分析[J].中华医学美学美容杂志,2007,13(1):1-4.
[9]周国瑜,沈玲悦,田克斌,等.长脉宽可调脉宽Gentle YAG 1064nm激光治疗颌面部血管瘤113例效果评估[J].上海口腔医学,2006,15(3):250-253.
[2]卢忠.皮肤激光医学与美容[M].上海:复旦大学出版社,2015:14,67-68.
[3]林晓曦,王炜,曹谊林.血管瘤和血管畸形治疗中的美容原则探讨[J].中华医学美学美容杂志,2003.6(9):190-192.
[4]Metka A,Agneta T,Maurice A,et a1.Vascular lasers and IPLS:Guidelines for care from the European Society for Laser Dermatology(ESLD)[J].J Cosmetic Laser Ther,2007,9(2):113-124.
[5]Wilder D.Pulsed 1 064nm Nd:YAG laser therapy for noninvasive treatment of a massive hemangioma:case report[J].J C1in Laser Med Surg,1999,17(6):245-247.
[6]Woo WK,Jasim ZF,Handley JM.532 nm Nd:YAG and 595 nm pulsed dye laser treatment of leg telangiectasia using ultralong pulse duration[J].Dermatol Surg,2003,29(12):1176-1180.
[7]黎宁,陈彦伟,池刚毅,等.强脉冲光治疗浅表(皮肤)血管瘤临床观察[J].中国美容医学,2007.16(6):792-794.
[8]刘盛秀,杨春俊,杨森,等.595 nm可调脉冲染料激光治疗皮肤血管异常性疾病疗效分析[J].中华医学美学美容杂志,2007,13(1):1-4.
[9]周国瑜,沈玲悦,田克斌,等.长脉宽可调脉宽Gentle YAG 1064nm激光治疗颌面部血管瘤113例效果评估[J].上海口腔医学,2006,15(3):250-253.