惠州地区定期健康体检的部分职业人群血脂水平的动态分析
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摘要
目的分析惠州地区部分职业人群定期血脂检查资料,了解其动态变化。方法选择2013-2016年连续4年每年都进行健康体检的人群,应用重复测量数据方差分析分析总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平变化,■趋势检验分析异常率变化。结果共有6 291名体检者,男性3 399人(54.0%),平均(41.2±13.3)岁。每年男性TC、TG、LDL-C水平均高于女性,而HDL-C水平要低于女性;男性和女性的血脂异常率(任一指标异常)从2013年35.7%和13.8%逐年降至2016年23.4%和11.7%(P<0.001,P=0.006);在4种血脂异常临床分型中,男性和女性高TC型、男性混合型异常率呈逐年下降趋势(从2013年3.9%、3.9%和2.8%分别降至2016年1.9%、2.5%和1.8%,且P均小于0.05);女性高TG型、男性和女性低HDL-C型异常率呈逐年上升趋势(从2013年4.0%、0.9%和0.3%分别升至2016年6.0%、7.4%和3.6%,且P均小于0.05)。结论定期健康体检人群总的血脂异常率呈现下降趋势,但在临床分型中,女性高TG型异常率、男性和女性低HDL-C型异常率却呈现上升趋势。
Objective To analyze the regular blood lipid examination data of some occupational groups in Huizhou area and to understand its dynamic changes.Methods Total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),and low-density lipoprotein cholesterol(LDL-C)were selected from people with regular health checkups from 2013 to 2016.Variance analysis of repeated measurement data was used to analyse blood lipid levels in different time,and ■ test was used to analysis dyslipidemia rate in different characteristic people.Results A total of 6 291 healthy subjects with 3 399 males(54.0%)were included,and the average age was 41.2±13.3 years.The levels of TC,TG,and LDL-C in males were higher than those in females,while that of HDL-C in males were lower than that in females.The dyslipidemia rate of males and females(any abnormality of indicators)decreased from 35.7% and 13.8% in 2013 to 23.4% and 11.7% in 2016(P<0.001,P=0.006).In the four clinical classifications of dyslipidemia,the abnormal rates of high TC type in males and females,and mixed type in males decreased year by year(from 3.9%,3.9% and 2.8% in 2013 to 1.9%,2.5% and 1.8% in 2016,respectively,and Ptrend<0.05).The abnormal rates of high TG type in females,low HDL-C in males and females increased year by year(from 4.0%,0.9% and 0.3% in 2013 to 6.0%,7.4% and 3.6% in 2016,respectively,and Ptrend<0.05).Conclusion The total dyslipidemia rate of the regular healthy checkups shows a downward trend,but in the clinical classification of dyslipidemia,the abnormal rates of high TG type in females and low HDL-C type in males and females show an upward trend.
Objective To analyze the regular blood lipid examination data of some occupational groups in Huizhou area and to understand its dynamic changes.Methods Total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),and low-density lipoprotein cholesterol(LDL-C)were selected from people with regular health checkups from 2013 to 2016.Variance analysis of repeated measurement data was used to analyse blood lipid levels in different time,and ■ test was used to analysis dyslipidemia rate in different characteristic people.Results A total of 6 291 healthy subjects with 3 399 males(54.0%)were included,and the average age was 41.2±13.3 years.The levels of TC,TG,and LDL-C in males were higher than those in females,while that of HDL-C in males were lower than that in females.The dyslipidemia rate of males and females(any abnormality of indicators)decreased from 35.7% and 13.8% in 2013 to 23.4% and 11.7% in 2016(P<0.001,P=0.006).In the four clinical classifications of dyslipidemia,the abnormal rates of high TC type in males and females,and mixed type in males decreased year by year(from 3.9%,3.9% and 2.8% in 2013 to 1.9%,2.5% and 1.8% in 2016,respectively,and Ptrend<0.05).The abnormal rates of high TG type in females,low HDL-C in males and females increased year by year(from 4.0%,0.9% and 0.3% in 2013 to 6.0%,7.4% and 3.6% in 2016,respectively,and Ptrend<0.05).Conclusion The total dyslipidemia rate of the regular healthy checkups shows a downward trend,but in the clinical classification of dyslipidemia,the abnormal rates of high TG type in females and low HDL-C type in males and females show an upward trend.
引文
[1] 陈灏珠,林果为.实用内科学[M].14版.北京:人民卫生出版社,2013:2101-2103.
[2] Moran A,Gu D,Zhao D,et al.Future cardiovascular disease in China:markov model and risk factor scenario projections from the coronary heart disease policy model-china[J].Circulation-Cardiovascular Quality and Outcomes,2010,3(3):243-252.
[3] 诸骏仁,高润霖,赵水平,等.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-953.
[4] 黄萍,张林波,陆志杰,等.广西地区常规体检人群血脂情况及血脂异常的影响因素分析[J].广西医科大学学报,2017,34(12):1781-1784.
[5] 张凤凤,王淑娥,李心河,等.血脂异常患者膳食摄入情况及相关危险因素研究[J].山东大学学报(医学版),2009,47(12):126-129.
[6] 顾子良,顾天伟,周卫红,等.南京城镇人群2009-2015年间血脂四项变化趋势的回顾性分析[J].贵州医药,2018,42(6):650-652.
[7] 马程乘,叶小琴,葛阳,等.杭州市某城市化社区人群血脂的变化趋势[J].中华健康管理学杂志,2018,12(4):307-312.
[8] 王欣,李曼,李晓梅,等.中国居民血脂水*平变动趋势分析[J].泰山医学院学报,2010,31(2):106-108.
[9] 尚菲菲.慢性病健康管理模式在健康体检中心的应用价值[J].河南医学研究,2018,27(6):1029-1030.
[10] 李凯,邱晶,王夏冬.张家港市中老年人血脂异常检出情况及危险因素分析[J].现代预防医学,2017,44(14):2549-2552.
[11] 夏颖,王颖,肖倩.北京地区2516名事业单位职工2010-2013年血脂情况的动态分析[J].中国健康教育,2014,30(4):366-368.
[12] 张莉,张蕊,殷珺妹,等.天津市成年体检人群血脂动态变化及血脂异常发生率的比较[J].中国慢性病预防与控制,2012,20(4):401-404.
[13] 刘建雷,马卫平,曾赤佳,等.定期健康体检对人群血糖、血脂控制情况的动态分析[J].国际检验医学杂志,2016,37(22):3153-3154.
[14] 王薇,赵冬,吴兆苏,等.中国11省市35～64岁人群血清甘油三酯分布特点及与其他心血管病危险因素关系的研究[J].中华流行病学杂志,2001,22(1):26-29.
[15] 李剑虹,米生权,李镒冲,等.2010年我国成年人血脂水平及分布特征[J].中华预防医学杂志,2012,46(7):607-612.
[16] 陈芳.女性绝经后雌激素水平与血脂、血糖和血同型半胱氨酸的关系研究[J].中国实验诊断学,2016,20(5):758-760.
[2] Moran A,Gu D,Zhao D,et al.Future cardiovascular disease in China:markov model and risk factor scenario projections from the coronary heart disease policy model-china[J].Circulation-Cardiovascular Quality and Outcomes,2010,3(3):243-252.
[3] 诸骏仁,高润霖,赵水平,等.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-953.
[4] 黄萍,张林波,陆志杰,等.广西地区常规体检人群血脂情况及血脂异常的影响因素分析[J].广西医科大学学报,2017,34(12):1781-1784.
[5] 张凤凤,王淑娥,李心河,等.血脂异常患者膳食摄入情况及相关危险因素研究[J].山东大学学报(医学版),2009,47(12):126-129.
[6] 顾子良,顾天伟,周卫红,等.南京城镇人群2009-2015年间血脂四项变化趋势的回顾性分析[J].贵州医药,2018,42(6):650-652.
[7] 马程乘,叶小琴,葛阳,等.杭州市某城市化社区人群血脂的变化趋势[J].中华健康管理学杂志,2018,12(4):307-312.
[8] 王欣,李曼,李晓梅,等.中国居民血脂水*平变动趋势分析[J].泰山医学院学报,2010,31(2):106-108.
[9] 尚菲菲.慢性病健康管理模式在健康体检中心的应用价值[J].河南医学研究,2018,27(6):1029-1030.
[10] 李凯,邱晶,王夏冬.张家港市中老年人血脂异常检出情况及危险因素分析[J].现代预防医学,2017,44(14):2549-2552.
[11] 夏颖,王颖,肖倩.北京地区2516名事业单位职工2010-2013年血脂情况的动态分析[J].中国健康教育,2014,30(4):366-368.
[12] 张莉,张蕊,殷珺妹,等.天津市成年体检人群血脂动态变化及血脂异常发生率的比较[J].中国慢性病预防与控制,2012,20(4):401-404.
[13] 刘建雷,马卫平,曾赤佳,等.定期健康体检对人群血糖、血脂控制情况的动态分析[J].国际检验医学杂志,2016,37(22):3153-3154.
[14] 王薇,赵冬,吴兆苏,等.中国11省市35～64岁人群血清甘油三酯分布特点及与其他心血管病危险因素关系的研究[J].中华流行病学杂志,2001,22(1):26-29.
[15] 李剑虹,米生权,李镒冲,等.2010年我国成年人血脂水平及分布特征[J].中华预防医学杂志,2012,46(7):607-612.
[16] 陈芳.女性绝经后雌激素水平与血脂、血糖和血同型半胱氨酸的关系研究[J].中国实验诊断学,2016,20(5):758-760.