艾灸效应的原理及功能的临床研究现状
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摘要
近些年,艾灸在疾病治疗中的运用愈加被重视,国内外对艾灸治疗的原理及作用机制的研究不断深入,本文通过查阅近几年的相关文献,对艾灸效应的原理及功能做出了详细的论述,并指出艾灸效应的原理并不仅仅是温热效应,而是由辐射、药化、创伤及综合等效应的综合作用结果。随着医学的进步与科研技术的发展,艾灸效应的应用也逐渐广泛,如抑制早期肿瘤细胞生长、改善血液循环、抗炎调节免疫功能、调节机体代谢、调节内分泌等。但是在艾灸与其他热源产品的疗效比较方面研究较少,因此在对艾灸效应定性分析取得一定成果的基础上,定量分析其作用的强度是很有必要的。
In recent years, the use of moxibustion in the treatment of diseases has been paid more and more attention.The research on the principle and mechanism of moxibustion treatment has been deepened at home and abroad. This paper examines the principles and functions of moxibustion effects by consulting relevant literature in recent years. A detailed discussion was made and it was pointed out that the principle of moxibustion effect is not only a warming effect, but a combination of effects such as radiation, pharmacology, trauma and synthesis. With the advancement of medicine and the development of scientific research technology, the application of moxibustion effect has gradually become widespread, such as inhibiting the growth of early tumor cells, improving blood circulation, anti-inflammatory regulation of immune function, regulating body metabolism, and regulating endocrine. However, there are few studies on the efficacy of moxibustion and other heat source products. Therefore, on the basis of qualitative results of the moxibustion effect, it is necessary to quantitatively analyze the intensity of its action.
In recent years, the use of moxibustion in the treatment of diseases has been paid more and more attention.The research on the principle and mechanism of moxibustion treatment has been deepened at home and abroad. This paper examines the principles and functions of moxibustion effects by consulting relevant literature in recent years. A detailed discussion was made and it was pointed out that the principle of moxibustion effect is not only a warming effect, but a combination of effects such as radiation, pharmacology, trauma and synthesis. With the advancement of medicine and the development of scientific research technology, the application of moxibustion effect has gradually become widespread, such as inhibiting the growth of early tumor cells, improving blood circulation, anti-inflammatory regulation of immune function, regulating body metabolism, and regulating endocrine. However, there are few studies on the efficacy of moxibustion and other heat source products. Therefore, on the basis of qualitative results of the moxibustion effect, it is necessary to quantitatively analyze the intensity of its action.
引文
[1]裘锡圭.长沙马王堆汉墓简帛集成(五)[M].北京:中华书局,2014.
[2]王玲玲.艾灸的特点及温通效应[J].中国针灸,2011,31(10):865-868.
[3]吕鹏,张承舜,尹海燕,等.艾灸温热刺激的研究现状[J].成都中医药大学学报,2017,40(1):95-98.
[4]柏文婕,邹卓诚.艾灸温通疗法治疗膝关节骨性关节炎的疗效观察[J].时珍国医国药,2015,26(2):397-400.
[5]Hongyong Deng,Xueyong Shen.The mechanism of moxibustion:ancient theory and modern research[J].Evid Based Complement Alternat Med,2013,9(12):1155.
[6]白耀辉,林文任.艾灸与温热刺激关系的探讨[J].针灸学报,1991,7(4):10-11.
[7]Park JH,Lee S,Du H.Far-infrared radiation acutely increases nitric oxide production by increasing Ca2+mobilization and Ca2+calmodulin-dependent protein kinaseⅡ-mediated phosphorylation of endothelial nitric oxide synthase at serine 1179[J].Biochem Biophys Res Commun,2013,436(4):601-606.
[8]龚长平,吴子建,何璐,等.艾烟作用的有效性和安全性研究概况[J].亚太传统医药,2017,13(1):53-56.
[9]惠鑫,黄畅,王昊,等.艾烟在艾灸中的作用机制及安全性[J].世界中医药,2017,12(9):2246-2251.
[10]温婧,高崚,王孟雨,等.透灸法临床应用心得[J].辽宁中医杂志,2018,45(2):363-365.
[11]周俊梅.艾灸对不同肿瘤模型的抑瘤机制研究[D].上海:上海交通大学,2015:59.
[12]刘平,潘秀颉,韩丽,等.长期艾烟干预对Wistar大鼠外周血T淋巴细胞亚群及CD4+CD25+Treg的影响[J].中国针灸,2013,33(2):145-148.
[13]张黎丹,杨红.选择性穴位艾灸在抗肿瘤治疗中导致白细胞减少症的应用[J].中医临床研究,2018,10(15):117-119.
[14]伍应芳.艾灸头部穴位对后循环缺血性眩晕的治疗效果[J].中西医结合研究,2016,8(4):182-184.
[15]黄年平,黄信全,付楝,等.银杏活脑胶囊联合艾灸头部穴位治疗后循环缺血性眩晕的疗效观察[J].中西医结合心脑血管病杂志,2018,16(9):1177-1179.
[16]王超,刘薇薇,黄洁,等.不同艾灸预处理时间对心肌缺血再灌注损伤大鼠心肌细胞中HIF-1α、Bcl-2及Caspase-3表达的影响[J].中医药学报,2017,45(4):70-74.
[17]张曼,胡修强,赵永华,等.杨骏教授临床灸法经验撷英[J].浙江中医药大学学报,2016,40(11):855-857.
[18]赵怡坤,朱田田,赵中亭,等.艾灸对类风湿关节炎免疫功能调节的机制研究进展[J].中国中医药信息杂志,2017,24(6):132-133.
[19]张宝双.艾灸联合抗生素治疗阑尾周围脓肿临床效果研究[J].基层医学论坛,2017,21(17):2261-2262.
[20]许晓洲,祝永福,夏黎明.艾灸治疗脾肾亏虚型癌因性疲乏临床研究[J].中医药临床杂志,2017,29(5):712-715.
[21]李梅.艾灸神阙穴对高脂血症小鼠调脂控炎的效应研究[D].南京:南京中医药大学,2016.
[22]和蕊,刘宏,王慧芳,等.艾灸对虚实辨证不同的原发性高血压患者中心动脉压的影响[J].中华中医药杂志,2018,33(6):2678-2681.
[23]刘宏,和蕊,罗智,等.艾灸疗法对高血压患者颈-股动脉脉搏波速度的影响[J].世界中医药,2018,13(2):456-459.
[24]沈洁,艾炳蔚,沈梅红.温和灸肾俞穴对绝经前后女性亚健康状态的干预[J].南京中医药大学学报,2015,31(6):532-535.
[25]邓小霞.艾灸水泉穴配合针刺治疗血寒型月经后期的临床疗效观察[D].福州:福建中医药大学,2018.
[2]王玲玲.艾灸的特点及温通效应[J].中国针灸,2011,31(10):865-868.
[3]吕鹏,张承舜,尹海燕,等.艾灸温热刺激的研究现状[J].成都中医药大学学报,2017,40(1):95-98.
[4]柏文婕,邹卓诚.艾灸温通疗法治疗膝关节骨性关节炎的疗效观察[J].时珍国医国药,2015,26(2):397-400.
[5]Hongyong Deng,Xueyong Shen.The mechanism of moxibustion:ancient theory and modern research[J].Evid Based Complement Alternat Med,2013,9(12):1155.
[6]白耀辉,林文任.艾灸与温热刺激关系的探讨[J].针灸学报,1991,7(4):10-11.
[7]Park JH,Lee S,Du H.Far-infrared radiation acutely increases nitric oxide production by increasing Ca2+mobilization and Ca2+calmodulin-dependent protein kinaseⅡ-mediated phosphorylation of endothelial nitric oxide synthase at serine 1179[J].Biochem Biophys Res Commun,2013,436(4):601-606.
[8]龚长平,吴子建,何璐,等.艾烟作用的有效性和安全性研究概况[J].亚太传统医药,2017,13(1):53-56.
[9]惠鑫,黄畅,王昊,等.艾烟在艾灸中的作用机制及安全性[J].世界中医药,2017,12(9):2246-2251.
[10]温婧,高崚,王孟雨,等.透灸法临床应用心得[J].辽宁中医杂志,2018,45(2):363-365.
[11]周俊梅.艾灸对不同肿瘤模型的抑瘤机制研究[D].上海:上海交通大学,2015:59.
[12]刘平,潘秀颉,韩丽,等.长期艾烟干预对Wistar大鼠外周血T淋巴细胞亚群及CD4+CD25+Treg的影响[J].中国针灸,2013,33(2):145-148.
[13]张黎丹,杨红.选择性穴位艾灸在抗肿瘤治疗中导致白细胞减少症的应用[J].中医临床研究,2018,10(15):117-119.
[14]伍应芳.艾灸头部穴位对后循环缺血性眩晕的治疗效果[J].中西医结合研究,2016,8(4):182-184.
[15]黄年平,黄信全,付楝,等.银杏活脑胶囊联合艾灸头部穴位治疗后循环缺血性眩晕的疗效观察[J].中西医结合心脑血管病杂志,2018,16(9):1177-1179.
[16]王超,刘薇薇,黄洁,等.不同艾灸预处理时间对心肌缺血再灌注损伤大鼠心肌细胞中HIF-1α、Bcl-2及Caspase-3表达的影响[J].中医药学报,2017,45(4):70-74.
[17]张曼,胡修强,赵永华,等.杨骏教授临床灸法经验撷英[J].浙江中医药大学学报,2016,40(11):855-857.
[18]赵怡坤,朱田田,赵中亭,等.艾灸对类风湿关节炎免疫功能调节的机制研究进展[J].中国中医药信息杂志,2017,24(6):132-133.
[19]张宝双.艾灸联合抗生素治疗阑尾周围脓肿临床效果研究[J].基层医学论坛,2017,21(17):2261-2262.
[20]许晓洲,祝永福,夏黎明.艾灸治疗脾肾亏虚型癌因性疲乏临床研究[J].中医药临床杂志,2017,29(5):712-715.
[21]李梅.艾灸神阙穴对高脂血症小鼠调脂控炎的效应研究[D].南京:南京中医药大学,2016.
[22]和蕊,刘宏,王慧芳,等.艾灸对虚实辨证不同的原发性高血压患者中心动脉压的影响[J].中华中医药杂志,2018,33(6):2678-2681.
[23]刘宏,和蕊,罗智,等.艾灸疗法对高血压患者颈-股动脉脉搏波速度的影响[J].世界中医药,2018,13(2):456-459.
[24]沈洁,艾炳蔚,沈梅红.温和灸肾俞穴对绝经前后女性亚健康状态的干预[J].南京中医药大学学报,2015,31(6):532-535.
[25]邓小霞.艾灸水泉穴配合针刺治疗血寒型月经后期的临床疗效观察[D].福州:福建中医药大学,2018.