高血压合并冠心病患者升主动脉弹性功能与不同冠脉病变的相关性分析
|
摘要
目的:分析高血压合并冠心病患者升主动脉弹性功能与不同冠脉病变的相关性,并探究其临床适用性。方法:选择从2012年4月~2014年9月于某院接受治疗的90例高血压合并冠心病患者作为研究病例,所有患者入院后均进行检测评价主动脉弹性及冠脉病变程度等,根据病变程度的不同,分为单支病变组、双支病变组及三支病变组3组。观察3组患者僵硬度、冠脉病变评分、升主动脉扩张性情况,并比较升主动脉前壁A、S、E波速度及动脉弹性参数。结果:三支病变组患者的僵硬度、冠脉病变评分、升主动脉扩张性均显著优于单支病变组及双支病变组,差异均具有统计学意义(P<0.05);双支病变组患者的僵硬度、冠脉病变评分、升主动脉扩张性均显著优于单支病变组(P<0.05);3组患者的升主动脉前壁A波及E波速度基本相符(P>0.05);三支病变组患者的升主动脉前壁S波速度显著优于双支病变组及单支病变组,差异具有统计学意义(P<0.05),双支病变组患者的升主动脉前壁S波速度显著优于单支病变组,两组比较,差异明显(P<0.05);3组患者的舒张压(DBP)、收缩压(SBP)、上肢动脉血压(AP)、平均动脉压(MAP)均基本相符(P>0.05);3组患者的动态血压的脉压(PP)比较,差异具有统计学意义(P<0.05)。结论:高血压合并冠心病患者升主动脉弹性功能降低与冠脉病变程度具有较为密切的关系,可以作为检测心血管的重要因子,适合临床长期推广应用。
Objective:To investigate the correlation between aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions,and to explore its clinical applicability.Methods:90cases of patients with hypertension and coronary heart disease treated in our hospital from April 2012 to September2014were taken as a research objects,who were examined in aortic elasticity and severity of coronary artery disease,and divided into single vessel lesion group,double vessel lesion group and three branch lesions group three groups according to the severity of coronary artery disease.Then observe the stiffness,coronary lesion score,ascending aortic distensibility of the three groups;and then compare the A,S,E wave velocity of ascending aorta anterior wall and artery elastic parameters.Results:The stiffness,coronary lesion score,ascending aortic distensibility of the three branch lesions group were significantly better than those of single vessel group and double vessel disease group,and the differences were statistically significant(P<0.05);The stiffness,coronary lesion score,ascending aortic distensibility of the double vessel lesion group were significantly better than those of single vessel group(P<0.05);anterior wall of ascending aorta of A wave and E wave velocity of the three groups were nearly consistent(P >0.05);anterior wall of ascending aorta S wave velocity of the three branch lesions group were significantly better than that of single vessel group and double vessel disease group,and the differences were statistically significant(P<0.05),anterior wall of ascending aorta S wave velocity of the double vessel lesion group were significantly better than that of single vessel group(P<0.05);the diastolic blood pressure(DBP),systolic blood pressure(SBP),upper extremity arterial blood pressure(AP),moving average Pulse pressure(MAP)of the three groups were basically consistent(P>0.05);the ambulatory blood pressure pulse pressure(PP)of the three groups and the difference was statistically significant(P<0.05).Conclusion:The aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions have close correlation.It can be used as an important factor to detect cardiovascular disease,which is suitable for clinical application.
Objective:To investigate the correlation between aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions,and to explore its clinical applicability.Methods:90cases of patients with hypertension and coronary heart disease treated in our hospital from April 2012 to September2014were taken as a research objects,who were examined in aortic elasticity and severity of coronary artery disease,and divided into single vessel lesion group,double vessel lesion group and three branch lesions group three groups according to the severity of coronary artery disease.Then observe the stiffness,coronary lesion score,ascending aortic distensibility of the three groups;and then compare the A,S,E wave velocity of ascending aorta anterior wall and artery elastic parameters.Results:The stiffness,coronary lesion score,ascending aortic distensibility of the three branch lesions group were significantly better than those of single vessel group and double vessel disease group,and the differences were statistically significant(P<0.05);The stiffness,coronary lesion score,ascending aortic distensibility of the double vessel lesion group were significantly better than those of single vessel group(P<0.05);anterior wall of ascending aorta of A wave and E wave velocity of the three groups were nearly consistent(P >0.05);anterior wall of ascending aorta S wave velocity of the three branch lesions group were significantly better than that of single vessel group and double vessel disease group,and the differences were statistically significant(P<0.05),anterior wall of ascending aorta S wave velocity of the double vessel lesion group were significantly better than that of single vessel group(P<0.05);the diastolic blood pressure(DBP),systolic blood pressure(SBP),upper extremity arterial blood pressure(AP),moving average Pulse pressure(MAP)of the three groups were basically consistent(P>0.05);the ambulatory blood pressure pulse pressure(PP)of the three groups and the difference was statistically significant(P<0.05).Conclusion:The aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions have close correlation.It can be used as an important factor to detect cardiovascular disease,which is suitable for clinical application.
引文
1赵云峰,郭杨,张洁,等.高血压病患者升主动脉弹性功能与冠状动脉狭窄程度的相关性.江苏医药,2011,37(20):2393~2396.
2 汤跃跃,金有靓,荆治,等.定量组织多普勒评价正常人及高血压患者升主动脉不同节段的弹性.实用医学杂志,2013,29(6):977~979.
3 蔚泓.高血压合并冠心病患者升主动脉弹性功能与冠脉病变的临床观察.中国保健营养(上旬刊),2014,24(7):3786.
4 李宁,赵鹏,柳澄,等.双源CT评估主动脉弹性的初步研究.中国医学影像技术,2011,27(5):953~957.
5 赵云峰,郭杨,张洁,等.高血压合并冠心病患者升主动脉弹性功能与冠脉病变的关系研究.齐齐哈尔医学院学报,2012,33(6):715~716.
6 由倍安,高海青,沈琳,等.冠心病患者颈动脉-股动脉脉搏波传导速度与升主动脉组织结构成分的相关性研究.中华老年医学杂志,2012,31(9):758~761.
7 王平,刘忠岐,林杰,等.组织多普勒成像技术评价肝硬化患者升主动脉弹性功能的探讨.中国临床研究,2014,27(8):984~985.
8 张怡,詹维伟,赵博,等.血管回声追踪及频谱多普勒技术评价大鼠腹主动脉弹性的对照研究.中华超声影像学杂志,2013,22(12):1075~1079.
9 张俊霞,徐金升,王双宇,等.镁离子在高磷诱导慢性肾衰竭大鼠胸主动脉血管钙化中的作用及机制研究.中国全科医学,2014,17(36):4324~4328.
10 张俊霞,徐金升,朱荣芳,等.慢性肾衰竭大鼠主动脉弹性功能与血管基质金属蛋白酶2表达及钙化间的关系.中国动脉硬化杂志,2014,22(2):115~120.
11 蒲朝霞,游向东,翁文超,等.颅内动脉瘤患者主动脉弹性功能变化及临床意义.浙江大学学报(医学版),2011,40(5):550~554.
2 汤跃跃,金有靓,荆治,等.定量组织多普勒评价正常人及高血压患者升主动脉不同节段的弹性.实用医学杂志,2013,29(6):977~979.
3 蔚泓.高血压合并冠心病患者升主动脉弹性功能与冠脉病变的临床观察.中国保健营养(上旬刊),2014,24(7):3786.
4 李宁,赵鹏,柳澄,等.双源CT评估主动脉弹性的初步研究.中国医学影像技术,2011,27(5):953~957.
5 赵云峰,郭杨,张洁,等.高血压合并冠心病患者升主动脉弹性功能与冠脉病变的关系研究.齐齐哈尔医学院学报,2012,33(6):715~716.
6 由倍安,高海青,沈琳,等.冠心病患者颈动脉-股动脉脉搏波传导速度与升主动脉组织结构成分的相关性研究.中华老年医学杂志,2012,31(9):758~761.
7 王平,刘忠岐,林杰,等.组织多普勒成像技术评价肝硬化患者升主动脉弹性功能的探讨.中国临床研究,2014,27(8):984~985.
8 张怡,詹维伟,赵博,等.血管回声追踪及频谱多普勒技术评价大鼠腹主动脉弹性的对照研究.中华超声影像学杂志,2013,22(12):1075~1079.
9 张俊霞,徐金升,王双宇,等.镁离子在高磷诱导慢性肾衰竭大鼠胸主动脉血管钙化中的作用及机制研究.中国全科医学,2014,17(36):4324~4328.
10 张俊霞,徐金升,朱荣芳,等.慢性肾衰竭大鼠主动脉弹性功能与血管基质金属蛋白酶2表达及钙化间的关系.中国动脉硬化杂志,2014,22(2):115~120.
11 蒲朝霞,游向东,翁文超,等.颅内动脉瘤患者主动脉弹性功能变化及临床意义.浙江大学学报(医学版),2011,40(5):550~554.