长蛇灸治疗腹泻型肠易激综合征(脾胃虚寒型)的临床观察
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摘要
目的探讨长蛇灸治疗腹泻型肠易激综合征(脾胃虚寒型)的临床效果。方法将2016年1月—2018年1月因脾胃虚寒型腹泻型肠易激综合征(IBS)于我院就诊的90例患者按随机数字表法分组。对照组45例采用马来酸曲美布汀片,观察组45例联合长蛇灸,4周为1疗程,比较2组症状改善及临床疗效情况。结果治疗后观察组畏寒肢冷、神疲乏力、食欲减退、腹泻等总症状积分低于对照组(P<0.05);治疗后观察组血浆中酪神经肽(NPY)水平高于对照组,胃肠肽(VIP)更低(P<0.05);观察组总有效率95.56%(43/45),高于对照组的77.78%(35/45),差异具统计学意义(P<0.05)。结论长蛇灸治疗脾胃虚寒型腹泻型IBS效果显著,可有效改善症状及胃肠激素,值得临床推广。
Objective To investigate the clinical effect of long snake moxibustion on diarrhea-predominant irritable bowel syndrome(spleen-stomach deficiency type). Methods From January 2016 to January 2018, 90 patients with diarrhea-type diarrhea-type irritable bowel syndrome(IBS) in our hospital were enrolled in the study and grouped according to random number table. The control group of 45 cases applied Qumebutine maleate tablets, and the observation group of 45 cases used long snake moxibustion. 4 weeks was a course of treatment. The improvement of symptoms and clinical efficacy in the two groups was compared. Results After treatment, the total symptom scores of chills, cold limbs, fatigue, loss of appetite and diarrhea in the observation group were lower than those in the control group( P<0.05). The level of plasma neuropeptide(NPY) in the observation group was higher than that in the control group. Gastrointestinal peptide(VIP) was lower(P<0.05). The total effective rate of the observation group was 95.56%(43/45), which was higher than that of the control group(77.78%(35/45)), the difference was statistically significant(P<0.05). Conclusion Long snake moxibustion is effective in treating spleen-deficiency type diarrhea-type IBS, which can effectively improve symptoms and gastrointestinal hormones. It is worth promoting.
Objective To investigate the clinical effect of long snake moxibustion on diarrhea-predominant irritable bowel syndrome(spleen-stomach deficiency type). Methods From January 2016 to January 2018, 90 patients with diarrhea-type diarrhea-type irritable bowel syndrome(IBS) in our hospital were enrolled in the study and grouped according to random number table. The control group of 45 cases applied Qumebutine maleate tablets, and the observation group of 45 cases used long snake moxibustion. 4 weeks was a course of treatment. The improvement of symptoms and clinical efficacy in the two groups was compared. Results After treatment, the total symptom scores of chills, cold limbs, fatigue, loss of appetite and diarrhea in the observation group were lower than those in the control group( P<0.05). The level of plasma neuropeptide(NPY) in the observation group was higher than that in the control group. Gastrointestinal peptide(VIP) was lower(P<0.05). The total effective rate of the observation group was 95.56%(43/45), which was higher than that of the control group(77.78%(35/45)), the difference was statistically significant(P<0.05). Conclusion Long snake moxibustion is effective in treating spleen-deficiency type diarrhea-type IBS, which can effectively improve symptoms and gastrointestinal hormones. It is worth promoting.
引文
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[9]王静.补中益气颗粒联合曲美布汀治疗脾胃虚弱证腹泻型肠易激综合征的疗效观察[J].现代药物与临床,2017,32(2):284-288.
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[2]刘新光.肠易激综合征与罗马Ⅲ诊断标准[J].胃肠病学,2006,11(12):736-738.
[3]赵艳.参苓白术散加减方联合匹维溴铵片治疗腹泻型肠易激综合征临床观察及其作用机制探讨[J].河北中医,2016,38(6):876-879,923.
[4] Van Oudenhove L,T rnblom H,St rsrud S,et al.Depression and somatization are associated with increased postprandial symptoms in patients with irritable bowel syndrom[J]. Gastroenterology,2016,150(4):866-874.
[5]王铁汉.枯草杆菌二联活菌肠溶胶囊联合马来酸曲美布汀治疗腹泻型肠易激综合征的疗效观察[J].中国医药指南,2013,11(2):33-34.
[6]赵迎盼,王凤云,杨俭勤,等.基于脑-肠互动异常的肠易激综合征发病机制的研究进展[J].中华医学杂志,2015,95(8):637-640.
[7]李茹柳,年立全,赵世清,等.党参对应激性溃疡和细胞迁移及多胺的影响[J].广州中医药大学学报,2013,30(4):519-524.
[8]王宏志,何仁胜,方春华,等.补脾益肠丸联合布拉氏酵母菌治疗腹泻型肠易激综合征临床疗效观察[J].时珍国医国药,2014,25(3):650-651.
[9]王静.补中益气颗粒联合曲美布汀治疗脾胃虚弱证腹泻型肠易激综合征的疗效观察[J].现代药物与临床,2017,32(2):284-288.
[10]方德宁.美沙拉嗪肠溶片治疗肠易激综合征的临床疗效[J].当代医学,2013,19(22):136-137.