水溶性蜂胶加工工艺的研究进展
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摘要
蜂胶具有广泛的生物学活性,但蜂胶在水中的溶解度极低,稳定性差,生物利用度低,因此其应用受到限制。如何使蜂胶均匀地分散于水中,对于蜂胶产品的开发和发挥蜂胶的保健功效有着重要的价值。该文介绍了水溶性蜂胶加工工艺的研究进展,重点介绍了使用乳化剂制备水溶性蜂胶的技术方法,评价了该技术用于蜂胶的适用性和存在的问题,旨在为蜂胶的深入研究和加工利用提供参考。
Propolis is a kind of bee products with various biological activities. Its application was limited,because of its poor solubility in water, low stability and bioavailability. How to make water-soluble propolis is very important for the development of propolis products and its health function.The research progress on the processing technology of water-soluble propolis was reviewedin this article.The research of water-soluble propolis using emulsifier was focused, and the applicability and problemof this technology for propoliswas evaluated,aimed to provided reference for the future research andapplications of propolis.
Propolis is a kind of bee products with various biological activities. Its application was limited,because of its poor solubility in water, low stability and bioavailability. How to make water-soluble propolis is very important for the development of propolis products and its health function.The research progress on the processing technology of water-soluble propolis was reviewedin this article.The research of water-soluble propolis using emulsifier was focused, and the applicability and problemof this technology for propoliswas evaluated,aimed to provided reference for the future research andapplications of propolis.
引文
[1]郑艳苹,付中民,杨文超,等.复合蜂胶乳剂抑菌试验研究[J].中国蜂业,2008,59(12):14-16.
[2]付中民,郑艳苹,杨文超,等.蜂胶乳化工艺的研究[J].中国蜂业,2008,59(11):5-8.
[3]郑艳萍.蜂胶乳化工艺及抑菌性研究[D].福州福建农林大学,2008.
[4]陈崇羔,邱忠平,沈利平.蜂胶水溶工艺的研究(一)---蜂胶增溶剂的筛选[J].中国养蜂,1999,50(5):3-5.
[5]陈崇羔.蜂胶水溶工艺的研究(二)---增溶剂与蜂胶的合适配比[J].中国养蜂,1999,50(6):5-7.
[6]王嘉军,张伟,王全立.蜂胶-银离子复合纳米乳剂杀菌机理的研究[J].中国消毒学杂志,2008,25(1):1-3.
[7]王嘉军,刘敏霞,王全立,等.蜂胶-银离子复合纳米乳剂的研制及其杀菌活性评价[J].中国消毒学杂志,2006,23(4):289-292.
[8]王嘉军,刘敏霞,王全立.壳聚糖-蜂胶复合纳米乳剂的研制及抑菌活性的检测[J].中国消毒学杂志,2005,22(3):241-243.
[9]YANG W,WU Z,HUANG Z Y,et al.Preservation of orange juice using propolis[J].Journal of Food Science and Technology,2017,54(11):3375-3383.
[10]何新益,王磊,符绳慧.乳化法制备水溶性蜂胶的研究[J].食品科技,2008,33(9):86-88.
[11]乞永艳,骆尚骅,刘富海,等.乳化剂对蜂胶抑菌作用的影响[J].中国养蜂,2001,52(5):4-5,10.
[12]侯振建,付子林,陈俊生,等.蜂胶纳米化技术研究[J].食品科学,2008,29(5):199-200.
[13]鲁传华,吴鸿飞,闵智伟.纳米蜂胶水分散体的制备工艺与配方研究[J].中成药,2008,30(5):674-677.
[14]骆小红,张伟,顾保东.蜂胶的微乳化及抗菌性能研究[C].北京,中国纳米技术应用研讨会,2004
[15]常亮,张利,曾里,等.蜂胶口腔保健喷剂的工艺[J].食品研究与开发,2010,31(11):118-121.
[16]曹炜.蜂胶产品加工工艺研究及其生物功能评价[D].西安,陕西师范大学,2001.
[17]MAULUDIN R,PRIMAVIRI DS,FIDRIANNY I.Nanoemulsion of ethanolic extracts of propolis and its antioxidant activity:International Conference on Mathematics&Natural Sciences,2015[C].
[18]孔令姗,刘田静,李晨晨,等.乳化对蜂胶活性成分抑菌作用研究[J].食品工业,2015,36(1):26-29.
[19]SULAIMAN F,KHILJEE S,NISAR U,et al.Formulation of microemulsion containing nigella sativa honey and propolis and evaluation of its burn healing potential[J].International Journal of Pharmaceutical Sciences Review&Research,2014,27(1):1-9.
[20]唐宏刚,肖朝耿,陈黎洪,等.高压均质法制备O/W型蜂胶纳米乳液的研究[J].浙江农业学报,2013,25(3):619-622.
[21]FAN Y,MA L,ZHANG W,et al.The design of propolis flavone microemulsion and its effect on enhancing the immunity and antioxidant activity in mice[J].International Journal of Biological Macromolecules,2014,65:200-207.
[22]FAN Y,MA L,ZHANG W,et al.Microemulsion can improve the immune-enhancing activity of propolis flavonoid on immunosuppression and immune response[J].International Journal of Biological Macromolecules,2014,63:126-132.
[23]SAHLAN M,PRAKOSO CD,DARWITA RR,et al.Formulation of microemulsion propolis fluoride(PF)as varnish topical agent to stop activity of teeth caries:Biomedical Engineerings Recent Progress in Biomaterials,Drugs Development,&Medical Devices[C].First International Symposium of Biomedical Engineering,2017.
[24]田进军,薛艳,侯振健.伪三元相图法制备O/W型蜂胶微乳[J].食品与机械,2011,27(3):127-129.
[25]DANTAS TNC,SILVA HSRC,DANTAS NETO AA,et al.Development of a new propolis microemulsion system for topical applications.[J].Revista Brasileira De Farmacognosia,2010,20(3):368-375.
[26]张旭,欧阳五庆,陈建民,等.复方蜂胶纳米乳的制备及其品质评价[J].西北农业学报,2010,19(5):24-27.
[27]HOMAYOONFAL M,KHODAIYAN F,MOUSAVI SM.Optimization of walnut oil nanoemulsions Prepared using ultrasonic emulsification:A response surface method[J].Journal of Dispersion Science&Technology,2014,35(5):685-694.
[28]KHAN NM,MU T,ALI F,et al.Effects of high hydrostatic pressure on emulsifying properties of sweet potato protein in model protein hydrocolloids system[J].Food Chemistry,2015,169:448-454.
[29]CHAE CH,PARK JW.The study on the effect of nanoemulsion for the prevention and treatment of gingival inflammation[J].Journal of Physical Activity&Health,2007,12(11):2955-2967.
[30]CHAE CH,CHOI DJ,SHIM HY,et al.Case reports:treatment of oral soft tissue lesions and wounds with high functional tooth paste made from nanoemulsion gel[J].J Korean Assoc Oral Maxillofac Surg,2007,33(6):694-700.
[31]游海,郑为完,高荫榆.蜂胶微胶囊粉末的研究[J].食品科学,2002,23(1):61-64.
[32]李雅晶,胡福良.纳米蜂胶的体外药剂学性质研究[J].中国蜂业,2007,58(7):5-6.
[33]BRUSCHI ML,CARDOSO MLC,Lucchesi MB,et al.Gelatin microparticles containing propolis obtained by spraydryingtechnique:preparation and characterization[J].International Journal of Pharmaceutics,2003,264(1-2):45-55.
[34]胡福良,李英华,朱威,等.不同方法提取的蜂胶液中总黄酮含量的测定及抗肿瘤与抗炎作用研究[J].中国食品学报,2005,5(3):11-15.
[35]何新益,符绳慧,王磊.水溶性蜂胶的酶解制备工艺优化[J].农业工程学报,2009,25(2):280-284.
[36]PARK YK,IKEGAKI M.Preparation of water and ethanolic extracts of propolis and evaluation of the preparations[J].Bioscience,Biotechnology,and Biochemistry,1998,62(11):2230-2232.
[2]付中民,郑艳苹,杨文超,等.蜂胶乳化工艺的研究[J].中国蜂业,2008,59(11):5-8.
[3]郑艳萍.蜂胶乳化工艺及抑菌性研究[D].福州福建农林大学,2008.
[4]陈崇羔,邱忠平,沈利平.蜂胶水溶工艺的研究(一)---蜂胶增溶剂的筛选[J].中国养蜂,1999,50(5):3-5.
[5]陈崇羔.蜂胶水溶工艺的研究(二)---增溶剂与蜂胶的合适配比[J].中国养蜂,1999,50(6):5-7.
[6]王嘉军,张伟,王全立.蜂胶-银离子复合纳米乳剂杀菌机理的研究[J].中国消毒学杂志,2008,25(1):1-3.
[7]王嘉军,刘敏霞,王全立,等.蜂胶-银离子复合纳米乳剂的研制及其杀菌活性评价[J].中国消毒学杂志,2006,23(4):289-292.
[8]王嘉军,刘敏霞,王全立.壳聚糖-蜂胶复合纳米乳剂的研制及抑菌活性的检测[J].中国消毒学杂志,2005,22(3):241-243.
[9]YANG W,WU Z,HUANG Z Y,et al.Preservation of orange juice using propolis[J].Journal of Food Science and Technology,2017,54(11):3375-3383.
[10]何新益,王磊,符绳慧.乳化法制备水溶性蜂胶的研究[J].食品科技,2008,33(9):86-88.
[11]乞永艳,骆尚骅,刘富海,等.乳化剂对蜂胶抑菌作用的影响[J].中国养蜂,2001,52(5):4-5,10.
[12]侯振建,付子林,陈俊生,等.蜂胶纳米化技术研究[J].食品科学,2008,29(5):199-200.
[13]鲁传华,吴鸿飞,闵智伟.纳米蜂胶水分散体的制备工艺与配方研究[J].中成药,2008,30(5):674-677.
[14]骆小红,张伟,顾保东.蜂胶的微乳化及抗菌性能研究[C].北京,中国纳米技术应用研讨会,2004
[15]常亮,张利,曾里,等.蜂胶口腔保健喷剂的工艺[J].食品研究与开发,2010,31(11):118-121.
[16]曹炜.蜂胶产品加工工艺研究及其生物功能评价[D].西安,陕西师范大学,2001.
[17]MAULUDIN R,PRIMAVIRI DS,FIDRIANNY I.Nanoemulsion of ethanolic extracts of propolis and its antioxidant activity:International Conference on Mathematics&Natural Sciences,2015[C].
[18]孔令姗,刘田静,李晨晨,等.乳化对蜂胶活性成分抑菌作用研究[J].食品工业,2015,36(1):26-29.
[19]SULAIMAN F,KHILJEE S,NISAR U,et al.Formulation of microemulsion containing nigella sativa honey and propolis and evaluation of its burn healing potential[J].International Journal of Pharmaceutical Sciences Review&Research,2014,27(1):1-9.
[20]唐宏刚,肖朝耿,陈黎洪,等.高压均质法制备O/W型蜂胶纳米乳液的研究[J].浙江农业学报,2013,25(3):619-622.
[21]FAN Y,MA L,ZHANG W,et al.The design of propolis flavone microemulsion and its effect on enhancing the immunity and antioxidant activity in mice[J].International Journal of Biological Macromolecules,2014,65:200-207.
[22]FAN Y,MA L,ZHANG W,et al.Microemulsion can improve the immune-enhancing activity of propolis flavonoid on immunosuppression and immune response[J].International Journal of Biological Macromolecules,2014,63:126-132.
[23]SAHLAN M,PRAKOSO CD,DARWITA RR,et al.Formulation of microemulsion propolis fluoride(PF)as varnish topical agent to stop activity of teeth caries:Biomedical Engineerings Recent Progress in Biomaterials,Drugs Development,&Medical Devices[C].First International Symposium of Biomedical Engineering,2017.
[24]田进军,薛艳,侯振健.伪三元相图法制备O/W型蜂胶微乳[J].食品与机械,2011,27(3):127-129.
[25]DANTAS TNC,SILVA HSRC,DANTAS NETO AA,et al.Development of a new propolis microemulsion system for topical applications.[J].Revista Brasileira De Farmacognosia,2010,20(3):368-375.
[26]张旭,欧阳五庆,陈建民,等.复方蜂胶纳米乳的制备及其品质评价[J].西北农业学报,2010,19(5):24-27.
[27]HOMAYOONFAL M,KHODAIYAN F,MOUSAVI SM.Optimization of walnut oil nanoemulsions Prepared using ultrasonic emulsification:A response surface method[J].Journal of Dispersion Science&Technology,2014,35(5):685-694.
[28]KHAN NM,MU T,ALI F,et al.Effects of high hydrostatic pressure on emulsifying properties of sweet potato protein in model protein hydrocolloids system[J].Food Chemistry,2015,169:448-454.
[29]CHAE CH,PARK JW.The study on the effect of nanoemulsion for the prevention and treatment of gingival inflammation[J].Journal of Physical Activity&Health,2007,12(11):2955-2967.
[30]CHAE CH,CHOI DJ,SHIM HY,et al.Case reports:treatment of oral soft tissue lesions and wounds with high functional tooth paste made from nanoemulsion gel[J].J Korean Assoc Oral Maxillofac Surg,2007,33(6):694-700.
[31]游海,郑为完,高荫榆.蜂胶微胶囊粉末的研究[J].食品科学,2002,23(1):61-64.
[32]李雅晶,胡福良.纳米蜂胶的体外药剂学性质研究[J].中国蜂业,2007,58(7):5-6.
[33]BRUSCHI ML,CARDOSO MLC,Lucchesi MB,et al.Gelatin microparticles containing propolis obtained by spraydryingtechnique:preparation and characterization[J].International Journal of Pharmaceutics,2003,264(1-2):45-55.
[34]胡福良,李英华,朱威,等.不同方法提取的蜂胶液中总黄酮含量的测定及抗肿瘤与抗炎作用研究[J].中国食品学报,2005,5(3):11-15.
[35]何新益,符绳慧,王磊.水溶性蜂胶的酶解制备工艺优化[J].农业工程学报,2009,25(2):280-284.
[36]PARK YK,IKEGAKI M.Preparation of water and ethanolic extracts of propolis and evaluation of the preparations[J].Bioscience,Biotechnology,and Biochemistry,1998,62(11):2230-2232.