复合丁酸梭菌对断奶仔猪生长性能及腹泻的影响
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摘要
本试验旨在研究饲粮中添加丁酸梭菌(Clostridium butyricum)对断奶仔猪生长性能及腹泻的影响。试验选取90头体重相近的"杜×长×大"断奶仔猪,随机分为3组,每组3个重复(栏),每个重复10头猪。各组分别饲喂基础饲粮(对照组),在基础饲粮基础上添加300 mg/kg土霉素钙+30 mg/kg亚甲基水杨酸杆菌肽(抗生素组)、500 mg/kg丁酸梭菌制剂(丁酸梭菌组)的试验饲粮,试验为期21天。结果表明:1)丁酸梭菌组仔猪ADG显著高于对照组(P <0.05),F/G显著低于对照组(P <0.05)。与抗生素组相比,丁酸梭菌组仔猪ADG及F/G无显著差异(P>0.05)。各组间仔猪ADFI差异不显著(P> 0.05)。2)丁酸梭菌组仔猪腹泻率及腹泻指数均显著低于对照组(P <0.05)。与抗生素组相比,丁酸梭菌组仔猪腹泻率及腹泻指数差异不显著(P>0.05)。因此,丁酸梭菌制剂可能在断奶仔猪上具有一定程度替代抗生素的潜力。
引文
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[14]LIAO X,MA J,CAI J,et al.Effects of Clostridium butyricum on growth performance,antioxidation,and immune function of broilers[J].Poultry Science,2015,94(4):662-667.
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[20]庞敏,卢庆萍,夏冰,等.酪酸梭菌对断奶仔猪生长性能、肠道组织形态及肠道通透性的影响[J].动物营养学报,2016,28(7):2113-2121.
[2]JENSEN H M.Health management with reduced antibiotic useExperiences of a Danish pig vet[J].Animal Biotechnology,2006,17:189-194.
[3]GALLOIS M,ROTHK?TTER H,BAILEY M,et al.Natural alternatives to in-feed antibiotics in pig production:can immunomodulators play a role?[J].Animal,2009,3:1644-1661.
[4]YANG K,JIANG Z,ZHENG C,et al.Effect of on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic K88[J].Journal of Animal Science,2014,92:1496-1503.
[5]FANG C,SUN H,WU J,et al.Effects of sodium butyrate on growth performance,hematological and immunological characteristics of weanling piglets[J].Journal of Animal Physiology and Animal Nutrition,2014,98(4):680-685.
[6]LIAO X,MA G,CAI J,et al.Effects of Clostridium butyricum on growth performance,antioxidation,and immune function of broilers[J].Poultry Science,2015,94(4):662-667.
[7]KNUDSEN K,SERENA A,CANIBE N,et al.New insight into butyrate metabolism[J].The Proceedings of the Nutrition Society,2003,62(1):81-86.
[8]PUERTOLLANO E,KOLIDA S,YAQOOB P.Biological significance of short-chain fatty acid metabolism by the intestinal microbiome[J].Current Opinion in Clinical Nutrition and Metabolic Care,2014,17(2):139-144.
[9]凌欣华,李鑫.复合丁酸梭菌对仔猪腹泻影响的效果试验报告[J].广东饲料,2016,25(6):22-26.
[10]MARQUARDT R,JIN L,JUNG-WOO K,et al.Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+infection in neonatal and early weaned piglets[J].FEMS Immunology and Medical Microbiology,1999,23:283-288.
[11]胡远亮.利用分子生物技术研究益生菌对断奶仔猪生长及粪便菌群的影响[D].武汉,华中农业大学,2014:79.
[12]郑有秀,王超,邹晓庭,等.丁酸梭菌对断奶仔猪生长性能、肠道结构和免疫功能的影响[J].动物营养学报,2018,30(7):2683-2689.
[13]胡红伟,张婵娟,闫凌鹏,等.丁酸梭菌作用机理及其在动物生产中的应用[J].饲料博览,2018(10):33-38.
[14]LIAO X,MA J,CAI J,et al.Effects of Clostridium butyricum on growth performance,antioxidation,and immune function of broilers[J].Poultry Science,2015,94(4):662-667.
[15]李玉鹏,李海花,王柳懿,等.丁酸梭菌对断奶仔猪生长性能、肠道屏障功能和血清细胞因子含量的影响[J].动物营养学报,2017,29(8):2961-2968.
[16]凌欣华,李鑫.复合丁酸梭菌对仔猪生长性能的影响试验[J].现代农业科技,2016(9):262.
[17]邢帅,朱琪,梁冬梅,等.丁酸梭菌缓解仔猪应激防御性大肠杆菌病[J].中国饲料,2018,7:54-58.
[18]ARAKI Y,ANDOH A,FUJIYAMA Y,et al.Oral administration of a product derived from Clostridium butyricum in rats[J].International Journal of Molecular Medicine,2002,9(1):53-57.
[19]HOSSAIN M,BEGUM M,KIM I.Effect of Bacillus subtilis,Clostridium butyricun and Lactobacillus acidophilus endospores on growth performance,nutrient digestibility,meat quality,relative organ weight,microbial shedding and excreta noxious gas emission in broilers[J].Journal of Veterinary Medical Science,2015,60(2):77-86.
[20]庞敏,卢庆萍,夏冰,等.酪酸梭菌对断奶仔猪生长性能、肠道组织形态及肠道通透性的影响[J].动物营养学报,2016,28(7):2113-2121.