单纯性肥胖儿童心功能的超声多模态分析研究进展
摘要
<正>单纯性肥胖是指机体持续性摄取超过基础代谢及活动所需热量导致脂肪组织堆积、体重高于正常标准的慢性疾病。WHO报告显示,亚洲有2 000万左右0～5岁儿童体重超过正常标准值~([1])。随着我国儿童饮食水平提高和运动量减少,儿童肥胖及超重率逐年上升,且城市儿童增幅明显大于农村儿童~([2])。有研究指出,单纯性肥胖儿童早期即存在心肌受累,造成心脏功能变化,且
引文
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[23]Levent E,Goksen D,Ozyurek AR,et al.Usefulness of the myocardial performance index(MPI)for assessing ventricular function in obese pediatric patients[J].Turk J Pediatr,2005,47(1):34-38.
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[25]Cameli M,Mondillo S,Galderisi M.Speckle tracking echocardiography a practical guide[J].Giornale Italiano Di Cardiologia,2017,18(4):253-269.
[26]Ojaghi-Haghighi Z,Mohebbi B,Moladoust H,et al.Left ventricular torsional parameters before and after atrial fibrillation ablation:a velocity vector imaging study[J].Electronic Physician,2017,9(9):5395-5401.
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[31]Yagmur J,Cansel M,Kurtoglu E,et al.Assessment of left atrial volume and function by real time three-dimensional echocardiography in obese patients[J].Echocardiography,2017,34(2):210-216.
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[33]王玥,崔文姬.实时三维超声心动图对右心室功能评价的应用进展[J].中国医学影像学杂志,2015,23(10):794-796.
[34]Leibundgut G,Rohner A,Grize L,et al.Dynamic assessment of right ventricular volumes and function by real-time threedimensional echocardiography:a comparison study with magnetic resonance imaging in 100 adult patients[J].J Am Soc Echocardiogr,2010,23(2):116-126.
[35]Squeri A,Censi S,Reverberi C,et al.Three-dimensional echocardiography in various types of heart disease:a comparison study of magnetic resonance imaging and 64-slice computed tomography in a real-world population[J].J Echocardiogr,2016,15(1):1-9.
[36]Abarca-Gómez L,Abdeen ZA,Hamid ZA,et al.Worldwide trends in body-mass index,underweight,overweight,and obesity from 1975 to2016:a pooled analysis of 2416 population-based measurement studies in 128.9 million children,adolescents,and adults[J].Lancet,2017,390(10113):2627-2642.
[2]Wang Y,Lobstein T.Worldwide trends in childhood overweight and obesity[J].Int J Pediatr Obes,2016,45(4):715-728.
[3]Koopman LP,Mertens LL.Impact of childhood obesity on cardiac structure and function[J].Curr Treat Options Cardiovasc Med,2014,16(11):345.DOI:10.1007/s11936-014-0345-y.
[4]Kim J,Lee I,Lim S.Overweight or obesity in children aged 0 to 6 and the risk of adult metabolic-syndrome:a systematic review and metaanalysis[J].J Clin Nurs,2017,26(23-24):3869-3880.
[5]Oana M,Jurgen D,Jens-Uwe V.Recent advances in echocardiography:strain and strain rate imaging[J].F1000Res,2016,5:787.DOI:10.12688/f1000research.7228.1.
[6]李梅,张晓蓉,薛爱玲.超声心动图检测单纯性肥胖儿童心脏功能的改变[J].中国临床医生杂志,2014,42(7):79-81.
[7]王丽丽.超声心动图评估单纯肥胖对青年人右心结构及功能的影响[D].南昌:南昌大学医学院硕士论文集,2014:146-179.
[8]鄢磊,阮琴韵,廖书生.多普勒超声心动图评价兔左心室舒张功能与充盈压[J].中国医学影像技术,2010,26(8):1424-1426.
[9]Rohani A,Poorzand H,Arefifar MR.E/Ea for the prediction of left atrial appendage thrombi in patients with atrial fibrillation and severe mitral stenosis[J].J Atr Fibrillation,2016,9(3):1447.DOI:10.4022/jafib.1447.
[10]魻ner T,魻zdemir R,Hazan F,et al.The association between brain natriuretic peptide and tissue doppler parameters in children with hypertrophic cardiomyopathy[J].Bosn J Basic Med Sci,2016,16(1):58-63.
[11]El Saiedi SA,Mira MF,Sharaf SA,et al.Left ventricular diastolic dysfunction without left ventricular hypertrophy in obese children and adolescents:a Tissue Doppler Imaging and Cardiac Troponin I Study[J].Cardiol Young,2017,28(1):1-9.
[12]Tei C,Ling LH,Hodge DO,et al.New index of combined systolic and diastolic myocardial performance:a simple and reproducible measure of cardiac function-a study in normals and dilated cardiomyopathy[J].J Cardiol,1995,26(6):357-366.
[13]Liu D,Hu K,Herrmann S,et al.Value of tissue Doppler-derived Tei index and two-dimensional speckle tracking imaging derived longitudinal strain on predicting outcome of patients with light-chain cardiac amyloidosis[J].Int J Cardiovasc Imaging,2017,33(6):837-845.
[14]周贵明,牛晓娜.超声心动图评估单纯肥胖儿童左心室功能的改变[J].中华临床医师杂志(电子版),2016,10(22):3334-3336.
[15]段洪梅,范梅贞.不同肥胖程度儿童左心功能状况[J].中国学校卫生,2009,30(3):277-277.
[16]段洪梅,张铁山,范梅贞,等.定量组织速度成像和组织追踪成像评价肥胖儿童左心功能[J].中国妇幼保健,2009,24(9):1218-1220.
[17]Sareen N,Ananthasubramaniam K.Strain imaging:from physiology to practical applications in daily practice[J].Cardiol Rev,2016,24(2):56-69.
[18]郭振伟,郭文彬,朱梅,等.应变率成像评价单纯性肥胖儿童左室局部心肌的收缩功能[J].医学影像学杂志,2008,18(5):478-480.
[19]Collier P,Phelan D,Klein A.A test in context:myocardial strain measured by speckle-tracking echocardiography[J].J Am Coll Cardiol,2017,69(8):1043-1056..
[20]Torrentguasp F,Kocica MJ,Corno AF,et al.Towards new understanding of the heart structure and function[J].Eur J Cardiothorac Surg,2005,27(2):191-201.
[21]Mangner N,Scheuermann K,Winzer E,et al.Childhood obesity:impact on cardiac geometry and function[J].JACC Cardiovasc Imaging,2014,7(12):1198-1205.
[22]Kibar AE,Pac FA,Ece I,et al.Effect of obesity on left ventricular longitudinal myocardial strain by speckle tracking echocardiography in children and adolescents[J].Balkan Med J,2015,32(1):56-63.
[23]Levent E,Goksen D,Ozyurek AR,et al.Usefulness of the myocardial performance index(MPI)for assessing ventricular function in obese pediatric patients[J].Turk J Pediatr,2005,47(1):34-38.
[24]邓艺雯,章春泉,许燕,等.三维斑点追踪技术评估单纯性肥胖儿童左室心肌应变早期变化[J].中国超声医学杂志,2018,34(3):217-220.
[25]Cameli M,Mondillo S,Galderisi M.Speckle tracking echocardiography a practical guide[J].Giornale Italiano Di Cardiologia,2017,18(4):253-269.
[26]Ojaghi-Haghighi Z,Mohebbi B,Moladoust H,et al.Left ventricular torsional parameters before and after atrial fibrillation ablation:a velocity vector imaging study[J].Electronic Physician,2017,9(9):5395-5401.
[27]Obert P,Gueugnon C,Nottin S,et al.Two‐dimensional strain and twist by vector velocity imaging in adolescents with severe obesity[J].Obesity,2012,20(12):2397-2405.
[28]朱秀玲,王均,李金英.速度向量成像技术对中青年单纯性肥胖患者左心室舒张功能的评价[J].华西医学,2015,30(12):2284-2285.
[29]Ruotsalainen H,Bellshamrevell H,Bell A,et al.Right ventricular systolic function in hypoplastic left heart syndrome:a comparison of velocity vector imaging and magnetic resonance imaging[J].Eur Heart J Cardiovasc Imaging,2016,17(6):687-692.
[30]Anwar AM,Nosir YF,Zainal-Abidin SK,et al.Real-time threedimensional transthoracic echocardiography in daily practice:initial experience[J].Cardiovasc Ultrasound,2012,10:14.DOI:10.1186/1476-7120-10-14.
[31]Yagmur J,Cansel M,Kurtoglu E,et al.Assessment of left atrial volume and function by real time three-dimensional echocardiography in obese patients[J].Echocardiography,2017,34(2):210-216.
[32]梅丽,岳超,杨晓英,等.实时三维超声心动图对青、中年肥胖者左室局部收缩功能的评价[J].中国实验诊断学,2012,16(1):71-73.
[33]王玥,崔文姬.实时三维超声心动图对右心室功能评价的应用进展[J].中国医学影像学杂志,2015,23(10):794-796.
[34]Leibundgut G,Rohner A,Grize L,et al.Dynamic assessment of right ventricular volumes and function by real-time threedimensional echocardiography:a comparison study with magnetic resonance imaging in 100 adult patients[J].J Am Soc Echocardiogr,2010,23(2):116-126.
[35]Squeri A,Censi S,Reverberi C,et al.Three-dimensional echocardiography in various types of heart disease:a comparison study of magnetic resonance imaging and 64-slice computed tomography in a real-world population[J].J Echocardiogr,2016,15(1):1-9.
[36]Abarca-Gómez L,Abdeen ZA,Hamid ZA,et al.Worldwide trends in body-mass index,underweight,overweight,and obesity from 1975 to2016:a pooled analysis of 2416 population-based measurement studies in 128.9 million children,adolescents,and adults[J].Lancet,2017,390(10113):2627-2642.