眼针结合益智汤治疗急性缺血性脑卒中认知障碍的疗效观察
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摘要
目的:观察眼针结合益智汤治疗急性缺血性脑卒中患者认知障碍的临床疗效。方法:将64例急性缺血性脑卒中伴认知障碍患者按照随机数字表分为治疗组(n=32)和对照组(n=32)。两组患者均予常规神经内外科治疗及专业认知训练,治疗组在此基础上进行眼针及益智汤治疗。采用MMSE、MoCA、ADL、WHOQOL-BREF量表对所有患者治疗前及治疗后8周进行认知功能、生活能力及生活质量评定。结果:治疗后两组的MMSE、MoCA、ADL、WHOQOL-BREF评分与治疗前相比均有改善,且治疗组优于对照组,治疗组疗效明显优于对照组。结论:针刺结合中药复方治疗明显改善急性缺血性脑卒中认知障碍的认知功能、生活能力及生活质量,具有较好的疗效。
Objective: To observe the clinical efficacy of eye-acupuncture combined with Yizhi Decoction in the treatment of cognitive impairment in patients with acute ischemic stroke. Methods: A total of 64 acute ischemic stroke patients with cognitive impairment were divided into treatment group( n = 32) and control group( n = 32) according to random number table. Two groups were given conventional neurosurgery and professional cognitive training. The treatment group on the basis used eye acupuncture and Yizhi Decoction treatment. The MMSE,MoCA,ADL and WHOQOL-BREF scales were used to evaluate the cognitive function,life skills and quality of life of all patients before treatment and 8 weeks after treatment. Results: The scores of MMSE,MoCA,ADL and WHOQOL-BREF in both groups were improved after treatment and the treatment group' s was better than the control group's. The curative effect of the treatment group was obviously better than that of the control group. Conclusion: Acupuncture combined with traditional Chinese medicine compound therapy can significantly improve the cognitive function,life ability and quality of life of patients with cognitive impairment in acute ischemic stroke and has good curative effect.
Objective: To observe the clinical efficacy of eye-acupuncture combined with Yizhi Decoction in the treatment of cognitive impairment in patients with acute ischemic stroke. Methods: A total of 64 acute ischemic stroke patients with cognitive impairment were divided into treatment group( n = 32) and control group( n = 32) according to random number table. Two groups were given conventional neurosurgery and professional cognitive training. The treatment group on the basis used eye acupuncture and Yizhi Decoction treatment. The MMSE,MoCA,ADL and WHOQOL-BREF scales were used to evaluate the cognitive function,life skills and quality of life of all patients before treatment and 8 weeks after treatment. Results: The scores of MMSE,MoCA,ADL and WHOQOL-BREF in both groups were improved after treatment and the treatment group' s was better than the control group's. The curative effect of the treatment group was obviously better than that of the control group. Conclusion: Acupuncture combined with traditional Chinese medicine compound therapy can significantly improve the cognitive function,life ability and quality of life of patients with cognitive impairment in acute ischemic stroke and has good curative effect.
引文
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[15]王炜,王鲁宁.“蒙特利尔认知评估量表”在轻度认知损伤患者筛查中的应用[J].中华内科杂志,2007,46(5):414-416.
[16]邹小香,张建英,连国民,等.轻度认知功能障碍患者生存质量与认知功能相关性研究[J].中国农村卫生事业管理,2014,34(6):675-677.
[17]彭静山.眼针疗法[J].中国针灸,1988,8(6):21-22.
[18]许春立,徐敉,王琦伟.治疗急性缺血性脑中风神经保护药物的进展和展望[J].大家健康(学术版),2016,10(13):152-153.
[19]林碧玉.针灸结合中医康复对认知功能障碍脑卒中患者的临床疗效观察[J].辽宁中医杂志,2018,45(3):605-608.
[20]刘琳,周鸿飞,董宝强.眼针疗法治疗中风病研究进展[J].辽宁中医杂志,2016,43(10):2232-2234.
[2]Song TJ,Kim J,Song D,et al.Total cerebral small-vessel diseasescore is associated with mortality during follow-up after acute ischemic Stroke[J].J Clin Neurol,2017,13(2):187-195.
[3]van den Berg LA,Dijkgraaf MG,Berkhemer OA,et al.Two-year outcome after endovascular treatment for acute ischemic stroke[J].N Engl J Med,2017,376(14):1341-1349.
[4]Sui R,Zhang L.Cerebellar dysfunction may play an important role in vascular dementia[J].Med Hypotheses,2012,78(1):162-165.
[5]吴逊.全国第四届脑血管病学术会议纪要[J].卒中与神经疾病,1997,4(2):51-55.
[6]贾建平.痴呆与轻度认知障碍的流行病学、发病机制和诊治应用研究---2013年度国家科学技术进步二等奖[J].首都医科大学学报,2014,35(1):1-5.
[7]田维柱.中华眼针[M].沈阳:辽宁科学技术出版社,2011:102-103.
[8]中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组.中国急性缺血性脑卒中诊治指南2010[J].中国全科医学,2011,14(35):4013-4017.
[9]De Carli C.Mild cognitive impairment:prevalence,prognosis,aetielegy,and treatment[J].Lancet Neurology,2003,2(1):15-21.
[10]徐亭亭.针刺结合康复对缺血性脑中风急性期功能恢复影响的临床研究[D].上海:上海中医药大学,2015.
[11]Jianzhong Li,Linlin Chen,Hongyuan Wu,et al.The Mixture of Salvianolic Acids from Salvia miltiorrhiza and Total Flavonoids from Anemarrhena asphodeloides Attenuate Sulfur Mustard-Induced Injury[J].Int J Mol Sci,2015,16(10):24555-24573.
[12]Park JH,Kim BJ,Bae HJ,et al.Impact of post-stroke cognitive impairment with no dementia on health-related quality of life[J].JStroke,2013,15(1):49-56.
[13]Carod-Artal FJ.Determining quality of life in stroke survivors[J].Expert Rev Pharmacoecon Outcomes Res,2012,12(2):199-211.
[14]唐娟娟,肖军.蒙特利尔认知评估量表与简易精神状态量表在认知功能障碍筛查中的应用与比较[J].实用医院临床杂志,2011,8(2):193-195.
[15]王炜,王鲁宁.“蒙特利尔认知评估量表”在轻度认知损伤患者筛查中的应用[J].中华内科杂志,2007,46(5):414-416.
[16]邹小香,张建英,连国民,等.轻度认知功能障碍患者生存质量与认知功能相关性研究[J].中国农村卫生事业管理,2014,34(6):675-677.
[17]彭静山.眼针疗法[J].中国针灸,1988,8(6):21-22.
[18]许春立,徐敉,王琦伟.治疗急性缺血性脑中风神经保护药物的进展和展望[J].大家健康(学术版),2016,10(13):152-153.
[19]林碧玉.针灸结合中医康复对认知功能障碍脑卒中患者的临床疗效观察[J].辽宁中医杂志,2018,45(3):605-608.
[20]刘琳,周鸿飞,董宝强.眼针疗法治疗中风病研究进展[J].辽宁中医杂志,2016,43(10):2232-2234.