肝硬化患者的凝血酶原时间和血小板的参数变化及其临床意义
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摘要
目的探究肝硬化患者的凝血酶原时间和血小板的参数变化及其临床意义,以供临床参考。方法选取某院2018年1月至2019年1月收治的108肝硬化例患者作为实验组研究对象。将实验组患者随机均分成出血组(肝硬化合并出血者,50例)、未出血组(肝硬化未合并出血者,58例)。同时选取同期于某院行体检的健康人群50例作为对照组。检测所有研究对象的PLT参数与PT水平。观察、对比出血组、未出血组患者及实验组、对照组PLT参数及PT水平。结果实验组与对照组PLT参数及PT水平相比,P<0.05,差异有统计学意义。出血组与未出血组患者PLT参数及PT水平相比,P<0.05,差异有统计学意义。结论临床在诊断肝硬化患者是否出血及肝功能受损程度时可通过PLT参数及PT水平进行评定,二者具有一定的临床诊断价值。
Objective To explore the changes of prothrombin time and platelet parameters in patients with cirrhosis and their clinical significance for clinical reference. Methods 108 patients with liver cirrhosis admitted to our hospital from January 2018 to January 2019 were selected as the experimental group. Patients in the experimental group were randomly divided into the bleeding group(50 patients with cirrhosis and hemorrhage) and the non-bleed group(58 patients with cirrhosis without bleeding). At the same time, 50 healthy people who were examined in our hospital during the same period were selected as the control group. PLT parameters and PT levels were measured for all subjects. PLT parameters and PT levels were observed and compared in the bleeding group, the non-bleeding group, the experimental group and the control group. Results Compared with the PLT parameters and PT levels in the experimental group and the control group, P<0.05, the difference was statistically significant. The PLT parameters and PT levels in the bleeding group and the non-bleeding group were P< 0.05, and the difference was statistically significant. Conclusion Clinical diagnosis of hepatic cirrhosis patients with bleeding and liver function damage can be assessed by PLT parameters and PT levels, both have a certain clinical diagnostic value.
Objective To explore the changes of prothrombin time and platelet parameters in patients with cirrhosis and their clinical significance for clinical reference. Methods 108 patients with liver cirrhosis admitted to our hospital from January 2018 to January 2019 were selected as the experimental group. Patients in the experimental group were randomly divided into the bleeding group(50 patients with cirrhosis and hemorrhage) and the non-bleed group(58 patients with cirrhosis without bleeding). At the same time, 50 healthy people who were examined in our hospital during the same period were selected as the control group. PLT parameters and PT levels were measured for all subjects. PLT parameters and PT levels were observed and compared in the bleeding group, the non-bleeding group, the experimental group and the control group. Results Compared with the PLT parameters and PT levels in the experimental group and the control group, P<0.05, the difference was statistically significant. The PLT parameters and PT levels in the bleeding group and the non-bleeding group were P< 0.05, and the difference was statistically significant. Conclusion Clinical diagnosis of hepatic cirrhosis patients with bleeding and liver function damage can be assessed by PLT parameters and PT levels, both have a certain clinical diagnostic value.
引文
[1]程宜,严志涵.肝硬化患者血小板相关参数和凝血指标的检测价值研究[J].临床输血与检验,2017,19(6):574-577.
[2]陈园园.肝硬化患者凝血酶原时间与血小板检验的临床价值分析[J].中国现代医药杂志,2018,20(2):68-70.
[3]王婷.肝硬化患者血小板、凝血功能的检测与肝硬化Child-Pugh分级的关系[J].中国实用医药,2017,12(7):35-37.
[4]郑秀诗.肝硬化患者凝血指标检测的临床意义研究[J].吉林医学,2018,39(3):449-450.
[5]廖艳辉.凝血酶原时间与血小板检验方式对肝硬化疾病患者进行诊断的临床价值研究[J].临床医药文献电子杂志,2017,4(12):77-78.
[6]李云霞.血小板(PLT)参数与凝血酶原时间(PT)在肝硬化患者临床检验中的价值[J].临床医药文献电子杂志,2016,3(36):132-133.
[7]李宏淼,马连学.凝血功能和血小板相关指标检测在肝硬化中的临床意义[J].中国现代药物应用,2016,10(1):33-34.
[8]向小红.肝硬化患者凝血酶原时间及血小板检验的临床价值[J].数理医药学杂志,2015(4):510-511.
[9]郝明.肝硬化患者凝血酶原时间及血小板的检验价值分析[J].中国卫生标准管理,2016,25(6):144-145.
[10]杨美荣,张国顺,刘斌,等.肝硬化患者血小板参数和凝血指标水平变化及意义[J].中华实用诊断与治疗杂志,2016,30(10):977-978.
[2]陈园园.肝硬化患者凝血酶原时间与血小板检验的临床价值分析[J].中国现代医药杂志,2018,20(2):68-70.
[3]王婷.肝硬化患者血小板、凝血功能的检测与肝硬化Child-Pugh分级的关系[J].中国实用医药,2017,12(7):35-37.
[4]郑秀诗.肝硬化患者凝血指标检测的临床意义研究[J].吉林医学,2018,39(3):449-450.
[5]廖艳辉.凝血酶原时间与血小板检验方式对肝硬化疾病患者进行诊断的临床价值研究[J].临床医药文献电子杂志,2017,4(12):77-78.
[6]李云霞.血小板(PLT)参数与凝血酶原时间(PT)在肝硬化患者临床检验中的价值[J].临床医药文献电子杂志,2016,3(36):132-133.
[7]李宏淼,马连学.凝血功能和血小板相关指标检测在肝硬化中的临床意义[J].中国现代药物应用,2016,10(1):33-34.
[8]向小红.肝硬化患者凝血酶原时间及血小板检验的临床价值[J].数理医药学杂志,2015(4):510-511.
[9]郝明.肝硬化患者凝血酶原时间及血小板的检验价值分析[J].中国卫生标准管理,2016,25(6):144-145.
[10]杨美荣,张国顺,刘斌,等.肝硬化患者血小板参数和凝血指标水平变化及意义[J].中华实用诊断与治疗杂志,2016,30(10):977-978.