摘要
目的:探讨蠲痹健膝方联合关节镜手术对膝骨关节炎的疗效。方法:选择膝骨关节炎病人80例作为研究对象,按照随机数字表法分为观察组和对照组,各40例。2组病人均接受关节镜手术治疗,对照组病人术后单纯接受功能锻炼,观察组病人术后给予蠲痹健膝方结合功能锻炼。采用Lysholm膝关节评分评价病人膝关节功能,采用疼痛视觉模拟评分评价病人疼痛程度,比较2组病人疗效,并比较治疗前后2组病人白细胞介素(IL)-1和肿瘤坏死因子α(TNF-α)水平变化。结果:治疗后2组病人Lysholm评分和VAS评分均较治疗前明显改善(P<0.01),且观察组均明显优于对照组(P<0.01)。2组病人治疗后IL-1和TNF-α水平均较治疗前明显下降(P<0.01),且观察组病人IL-1、TNF-α水平均明显低于对照组(P<0.01)。观察组治疗总有效率为95.00%(38/40),对照组为72.50%(29/40);观察组疗效优于对照组(P<0.05)。结论:蠲痹健膝方联合关节镜手术治疗膝骨关节炎疗效较好,并能有效降低炎症因子水平,值得临床推广。
Objective:To investigate the effects of Juanbi Jianxi recipe combined with arthroscopic surgery in the treatment of knee osteoarthritis.Methods:Eighty patients with knee osteoarthritis were randomly divided into the observation group and control group(40 cases each group).Two groups were treated with arthroscopic surgery,and then the control group and observation group were treated with functional training and Juanbi Jianxi recipe combined with functional training,respectively.The knee joint function score and pain in two groups were evaluated using Lysholm knee joint function scale and visual analogue scale(VAS),and the levels of IL-1 and TNF-α in two groups between before and after treatment were compared.Results:After treatment,the scores of Lysholm and VAS in two groups were significantly improved compared with before with treatment(P<0.01),and which in observation group was significantly better than that in control group(P<0.01).After treatment,the levels of IL-1 and TNF-α in two groups significantly decreased compared before treatment(P<0.01),and which in observation group was significantly lower than that in control group(P<0.01).The total effective rates in observation group and control group were 95.00%(38/40) and 72.50%(29/40),respectively.The treatment effect in observation group was better than that in control group(P<0.05).Conclusions:The effects of Juanbi Jianxi recipe combined with arthroscopic surgery in the treatment of knee osteoarthritis are good,which can effectively decrease the level of inflammatory factor,and is worthy of promotion in clinic.
引文
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