口腔黏膜下纤维化中医临床诊疗方案
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摘要
目的:介绍口腔黏膜下纤维化(oral submucous fibrosis,OSF)的中医诊疗方案。方法:根据中医辨证施治原则,将OSF诊断和治疗可分为:气滞血瘀证,治疗原则是理气活血,化瘀软坚;痰毒蕴结证,治疗原则是理气化痰,软坚散结;气血亏虚证,治疗原则是补益气血,调和营卫。提供3个典型病例的诊断和治疗。结果:3个典型病例分别诊断为气滞血瘀证、痰毒蕴结证和气血亏虚证,经辨施治1～2月,2～3阶段,随访4～8年,1例痊愈,无复发,2例症状缓解。结论:中医药辨证施治对OSF有一定疗效。
Objective: To introduce the strategy of the treatment of oral submucous fibrosis( OSF) with traditinal chinese medicine.Methods: According to the basic theorie of traditional Chinese medicine,treatment based on syndrome differentiation,OSF was diagnosed as Qi and blood stasis( QBS) treated by regulating qi and promoting blood circulation; sputum poision accumulate knot card( SPAKC) treated by regulating Qi and resolving phlegm; and Qi deficiency syndram( QDS) treated by invigorating Qi and blood,regulating ying and wei. resoluing phlegm and softing hard masses,Qi and blood toni were used for QBS,SAPKC and QDS respectively. Results:The 3 cases were diagnosed with QBS,SPAKC and QDS,underwent the treatment based on syndrome differentiation for 1 ～ 2 month with2-3 stages. After 4-8 years-follow-up,cure was observed in 1 case,remission in 2 cases. Conclusion: Traditional Chinese medical trerapy bassed on syndrome differentiation is effective in the treatment of OSF.
Objective: To introduce the strategy of the treatment of oral submucous fibrosis( OSF) with traditinal chinese medicine.Methods: According to the basic theorie of traditional Chinese medicine,treatment based on syndrome differentiation,OSF was diagnosed as Qi and blood stasis( QBS) treated by regulating qi and promoting blood circulation; sputum poision accumulate knot card( SPAKC) treated by regulating Qi and resolving phlegm; and Qi deficiency syndram( QDS) treated by invigorating Qi and blood,regulating ying and wei. resoluing phlegm and softing hard masses,Qi and blood toni were used for QBS,SAPKC and QDS respectively. Results:The 3 cases were diagnosed with QBS,SPAKC and QDS,underwent the treatment based on syndrome differentiation for 1 ～ 2 month with2-3 stages. After 4-8 years-follow-up,cure was observed in 1 case,remission in 2 cases. Conclusion: Traditional Chinese medical trerapy bassed on syndrome differentiation is effective in the treatment of OSF.
引文
[1]陈谦明.口腔黏膜病学[M].北京:人民卫生出版社,2015:127-131.
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[3]隋嘉宁,陈世娟,李元聪.李元聪教授治疗口腔黏膜下纤维化临证经验[J].湖南中医药大学学报,2018,38(4):424-426.
[4]王达,柳志文,章乐怡,等.复方当归注射液对肌成纤维细胞增殖和凋亡影响的研究[J].中南药学,2014,12(8):775-778.
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[6]陈思源,叶琦.槟榔碱引发口腔黏膜下纤维性变及癌变的研究进展[J].医药导报,2013,32(5):133-134.
[7]谭劲,吴丹,刘寻,等.从虚瘀痰毒探讨口腔黏膜下纤维化的发病机制[J].湖南中医药大学学报,2016,36(3):38-39.
[8]翦新春,高兴,李宁.口腔黏膜下纤维性变的免疫学研究进展[J].北京口腔医学,2011,19(1):1-3.
[9]凌天牖,高义军,唐杰青.口腔黏膜下纤维性变患者外周血NK细胞活性的研究[J].华西口腔医学杂志,1996,14(1):23-24.
[10]谭劲,周小青.口腔黏膜下纤维化中西医研究进展[J].世界最新医学信息文摘,2016,16(14):31-32.
[2]中华口腔医学会口腔黏膜病专业委员会.口腔黏膜下纤维性变的诊断标准[J].中华口腔医学杂志,2009,44(3):131.
[3]隋嘉宁,陈世娟,李元聪.李元聪教授治疗口腔黏膜下纤维化临证经验[J].湖南中医药大学学报,2018,38(4):424-426.
[4]王达,柳志文,章乐怡,等.复方当归注射液对肌成纤维细胞增殖和凋亡影响的研究[J].中南药学,2014,12(8):775-778.
[5]谭劲,李元聪,陈安,等.丹玄口康治疗口腔黏膜下纤维化的临床研究[J].湖南中医药大学学报,2006,26(5):41-43.
[6]陈思源,叶琦.槟榔碱引发口腔黏膜下纤维性变及癌变的研究进展[J].医药导报,2013,32(5):133-134.
[7]谭劲,吴丹,刘寻,等.从虚瘀痰毒探讨口腔黏膜下纤维化的发病机制[J].湖南中医药大学学报,2016,36(3):38-39.
[8]翦新春,高兴,李宁.口腔黏膜下纤维性变的免疫学研究进展[J].北京口腔医学,2011,19(1):1-3.
[9]凌天牖,高义军,唐杰青.口腔黏膜下纤维性变患者外周血NK细胞活性的研究[J].华西口腔医学杂志,1996,14(1):23-24.
[10]谭劲,周小青.口腔黏膜下纤维化中西医研究进展[J].世界最新医学信息文摘,2016,16(14):31-32.