联合应用壳聚糖宫颈抗菌膜及多西环素治疗非淋菌性宫颈炎的疗效观察
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摘要
目的探讨壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的效果。方法选取2017年1～12月在我院门诊就诊的非淋菌性宫颈炎80例女性患者作为研究对象,随机分为对照组和实验组,各40例。对照组仅给予多西环素治疗,实验组给予壳聚糖宫颈抗菌膜和多西环素治疗,比较两组的临床疗效及不良反应。结果实验组临床总有效率较对照组明显增高(P <0.05),不良反应无统计学差异(P> 0.05)。结论联合应用壳聚糖宫颈抗菌膜及多西环素治疗非淋菌性宫颈炎的临床效果显著,能明显改善临床症状,不良反应少,安全性高,复发率低,值得临床推广应用。
Objective To explore the curative effects of chitosan cervical antibacterial membrane combined with doxycycline in treatment of non-gonococcal cervicitis. Methods 80 patients with nongonococcal cervicitis who were treatment in outpatient department of our hospital from January 2017 to December 2017 were selected as research objects. They were randomly divided into the control group and the experimental group, with cases in each group. The control group was treated with doxycycline while the experimental group was treated with chitosan cervical antibacterial membrane combined with doxycycline. The clinical curative effects and adverse reactions between the two groups were compared. Results Compared with the control group, the total effective rate of the experimental group was significantly higher(P < 0.05). There was no statistically significant difference in adverse reactions between two groups(P > 0.05). Conclusion The clinical curative effects of chitosan cervical antibacterial membrane combined with doxycycline in treatment of non-gonococcal cervicitis are significant. It can significantly improve clinical symptoms and it has few adverse reactions, high safety and low recurrence rate. It is worth promoting and applying in clinical practice.
Objective To explore the curative effects of chitosan cervical antibacterial membrane combined with doxycycline in treatment of non-gonococcal cervicitis. Methods 80 patients with nongonococcal cervicitis who were treatment in outpatient department of our hospital from January 2017 to December 2017 were selected as research objects. They were randomly divided into the control group and the experimental group, with cases in each group. The control group was treated with doxycycline while the experimental group was treated with chitosan cervical antibacterial membrane combined with doxycycline. The clinical curative effects and adverse reactions between the two groups were compared. Results Compared with the control group, the total effective rate of the experimental group was significantly higher(P < 0.05). There was no statistically significant difference in adverse reactions between two groups(P > 0.05). Conclusion The clinical curative effects of chitosan cervical antibacterial membrane combined with doxycycline in treatment of non-gonococcal cervicitis are significant. It can significantly improve clinical symptoms and it has few adverse reactions, high safety and low recurrence rate. It is worth promoting and applying in clinical practice.
引文
[1]王瑞,邓艳丽.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的疗效分析[J].实用妇科内分泌杂志,2017,4(15):16-19.
[2]王寒星.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的疗效分析[J].西藏医药,2017,38(6):13-15.
[3]李汉平,许光珍,麦金秀,等.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的效果观察[J].吉林医学,2016,37(10):2536-2537.
[4]陈慧姮,张锡宝.多西环素作为抗炎药物在皮肤科应用的新进展[J].皮肤性病诊疗学杂志,2017,24(3):223.
[5]孟桂敏,张淑珍.宫颈环形电极切除术联合壳聚糖抗菌膜治疗宫颈病变临床观察[J].军事医学科学院院刊,2009,33(5):499-500.
[6]熊辉,熊丹东,黎筱青.止血敷料在经桡动脉途径冠状动脉介入治疗中的应用[J].江西医药, 2017, 52(10):1015-1016.
[7]张霞忠,周文俊,谭钊.壳聚糖膜在医学方面的应用研究进展[J].化工新型材料,2017,45(4):21-23.
[8]陈道玉,张中民,姜丽丽.壳聚糖支架材料在组织工程中的应用与未来[J].中国组织工程研究,2017, 21(30):4893-4900.
[9]龙尾,汤卫华,吕春晖,等.壳聚糖及其衍生物在食品工业中的应用[J].食品安全导刊, 2016,15:122.
[10]李玉寒,卞君醒,狄斌.壳聚糖复合创面敷料研究进展[J].药物生物技术,2017,24(4):369-372.
[11]曾金花.壳聚糖宫颈抗菌膜联合宫颈环形电切术治疗宫颈糜烂效果分析[J].当代医学,2016,22(22):68-69.
[12]袁捷.74例非淋菌性宫颈炎的临床治疗效果分析[J].中国城乡企业卫生,2017,32(7):56-57.
[13]李勇莉.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的疗效分析[J].北方医学,2017,14(11):25.
[14]郭大庆,刘艳媚,廖庆梅,等.壳聚糖碘治疗CINⅠ伴高危HPV感染的疗效观察[J].北方药学,2016,13(3):34-35.
[15]王芳宇,张启锋,何丽芳,等.壳聚搪碘液体外抗人单纯疱疹病毒2型的作用[J].中国皮肤性病学杂志,2011, 25(2):101-103.
[2]王寒星.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的疗效分析[J].西藏医药,2017,38(6):13-15.
[3]李汉平,许光珍,麦金秀,等.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的效果观察[J].吉林医学,2016,37(10):2536-2537.
[4]陈慧姮,张锡宝.多西环素作为抗炎药物在皮肤科应用的新进展[J].皮肤性病诊疗学杂志,2017,24(3):223.
[5]孟桂敏,张淑珍.宫颈环形电极切除术联合壳聚糖抗菌膜治疗宫颈病变临床观察[J].军事医学科学院院刊,2009,33(5):499-500.
[6]熊辉,熊丹东,黎筱青.止血敷料在经桡动脉途径冠状动脉介入治疗中的应用[J].江西医药, 2017, 52(10):1015-1016.
[7]张霞忠,周文俊,谭钊.壳聚糖膜在医学方面的应用研究进展[J].化工新型材料,2017,45(4):21-23.
[8]陈道玉,张中民,姜丽丽.壳聚糖支架材料在组织工程中的应用与未来[J].中国组织工程研究,2017, 21(30):4893-4900.
[9]龙尾,汤卫华,吕春晖,等.壳聚糖及其衍生物在食品工业中的应用[J].食品安全导刊, 2016,15:122.
[10]李玉寒,卞君醒,狄斌.壳聚糖复合创面敷料研究进展[J].药物生物技术,2017,24(4):369-372.
[11]曾金花.壳聚糖宫颈抗菌膜联合宫颈环形电切术治疗宫颈糜烂效果分析[J].当代医学,2016,22(22):68-69.
[12]袁捷.74例非淋菌性宫颈炎的临床治疗效果分析[J].中国城乡企业卫生,2017,32(7):56-57.
[13]李勇莉.壳聚糖宫颈抗菌膜联合多西环素治疗非淋菌性宫颈炎的疗效分析[J].北方医学,2017,14(11):25.
[14]郭大庆,刘艳媚,廖庆梅,等.壳聚糖碘治疗CINⅠ伴高危HPV感染的疗效观察[J].北方药学,2016,13(3):34-35.
[15]王芳宇,张启锋,何丽芳,等.壳聚搪碘液体外抗人单纯疱疹病毒2型的作用[J].中国皮肤性病学杂志,2011, 25(2):101-103.